Navigation Links
'Very low' risk of infections in advanced brain procedures
Date:3/4/2013

Philadelphia, Pa. (March 4, 2013) Patients undergoing cerebral angiography and neurointerventional procedures on the brain are at very low risk of infectioneven without preventive antibiotics, reports a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

"These data suggest that the overall risk of infection associated with most neuroangiographic procedures is very low," according to the study by Dr. Prashant S. Kelkar and colleagues of University of Alabama, Birmingham. Based on their results, the researchers believe routine preventive antibiotics may not be needed for patients undergoing brain angiography and interventions.

Out of 2,900 Procedures, Just Three Infections
The authors reviewed their experience with more than 2,900 cerebral angiograms and neurointerventional procedures performed between 2004 and 2011. An angiogram is an x-ray procedure using a special dye injected into the brain blood vessels. Neurointerventional procedures are various types of minimally invasive (nonsurgical) procedures performed to treat brain lesions such as aneurysms.

Both types of procedures are performed by threading a catheter through the patient's blood vesselsusually accessing the femoral artery through a tiny incision in the upper thigh. Unlike at some other centers, the authors did not routinely give antibiotics to prevent infections in patients undergoing these procedures.

The experience included approximately 2,000 angiographic and 900 neurointerventional procedures. Just three patients had infections directly attributable to the procedurea rate of one-tenth of one percent (0.1%). All were localized infections involving the femoral artery access site in the thigh. There were no infections of the brain or central nervous system.

All infections were successfully treated with antibiotics; two of the patients underwent minor surgery as well. In one patient, the infection was likely related to suppressed immune function because of cancer treatment. None of the patients died as a result of their infection.

Routine Antibiotics May Be Unnecessary
Cerebral angiography is a common diagnostic test for patients with stroke and other disorders. Neurointerventional procedures provide a less-invasive alternative to surgery for selected patients with aneurysms or other lesions of the brain blood vessels.

At many hospitals, patients undergoing these procedures are routinely given antibiotics to prevent infections. However, few studies have evaluated the risk of infection in patients undergoing cerebral angiography and neurointerventional procedures.

The new study finds that the risk of infection is very low, even without routine use of antibiotics. The authors suggest the low risk of infection may reflect the minimally invasive nature of these procedures; their short duration, compared to brain surgery; and the "blood-brain barrier" preventing bacteria from crossing from the bloodstream into the brain.

Dr. Kelkar and colleagues believe their results question the need for routine antibiotics for patients undergoing these procedures. "Prophylatic antibiotic use may be a reasonable option for selected patients," they write, "but is probably unnecessary for standard use in the context of meticulous care during procedures."


'/>"/>

Contact: Connie Hughes
connie.hughes@wolterskluwer.com
Wolters Kluwer Health
Source:Eurekalert

Related medicine news :

1. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
2. Recovery from propofol anesthesia may be sped by use of common stimulant
3. Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
4. Washingtons Life Sciences Discovery Fund awards commercialization grants
5. Head, Body Lice Are Genetically Very Similar
6. Discovery could help to develop drugs for organ transplant and cancer patients
7. Weight-Loss Surgery Beat Drugs for Cutting Diabetes in Very Obese
8. Feelings of immaturity accompany alcohol misuse into adulthood; discovery could improve treatments
9. Everyday Activities Might Lower Alzheimers Risk
10. Everyday fish oil capsule may provide kidney-related benefits
11. New report shows 15 million babies born too soon every year
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... January 20, 2017 , ... Source Vitál Apothecary, a skin and ... essential oils, announced the company had a successful visit to the 2017 ECRM Diet, ... gives companies that work in the nutritional, sports and health industries a chance to ...
(Date:1/20/2017)... ... January 20, 2017 , ... Bionic Sports Nutrition LLC, an American ... announced it had a successful January ECRM Trade Show in Hilton Head, SC. ... which allows it to provide its products to all clients at reasonable prices. At ...
(Date:1/20/2017)... ... January 20, 2017 , ... ... enhance people’s everyday lives, recently attended the January ECRM Trade Show in Hilton ... is known for its large range of supplements that keep the body functioning ...
(Date:1/20/2017)... ... 2017 , ... Michael and Betsy Brauser celebrated 5 years of Betsy’s participation ... trial has been life-saving as she has been on the trial for more ... diagnosed with ovarian cancer in 2009. She underwent standard chemotherapy but a year later ...
(Date:1/20/2017)... , ... January 20, 2017 , ... ... and its sugar-free alternative VW+ 002. The drinks have been produced in collaboration ... conditions to perform during your workout. , After a successful launch in Sweden ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... Jan 20, 2017 Research and Markets ... Testing Market By Type of Test (Tumor, Clinical Chemistry, Microbiology, ... Type of Diseases (Tuberculosis, Influenza, Cancer, HIV/AIDS etc.), Forecast to ... ... for healthcare services, market segments, especially clinical lab testing, which ...
(Date:1/21/2017)... Calif. , Jan. 20, 2017 ARMO ... 1b clinical data on the Company,s lead investigational immuno-oncology ... Symposium, co-sponsored by the American Society of Clinical Oncology ... San Francisco, CA. "AM0010 ... activated CD8 + T cells in the blood ...
(Date:1/21/2017)... YORK , Jan. 20, 2017  Faruqi & Faruqi, ... KemPharm, Inc. ("KemPharm" or the "Company") (NASDAQ: KMPH ... the Company and certain officers and directors and underwriters of ... to seek the role of lead plaintiff. The ... District Court for Johnson County ...
Breaking Medicine Technology: