Navigation Links
Vertebroplasty: Integral to treating back pain in blood marrow cancer patients

TAMPA, Fla. (March 15, 2010)Treating non-osteoporotic compression fractures in patients with multiple myeloma, a blood cancer, shows that the use of vertebroplastya minimally invasive treatment performed by interventional radiologists using imaging guidance that stabilizes collapsed vertebrae with the injection of medical-grade bone cement into the spineresults in a reduction of pain, medication usage and disability, according to researchers in the largest study of its kind at the Society of Interventional Radiology's 35th Annual Scientific Meeting in Tampa, Fla.

"The minimally invasive, image-guided treatment of vertebroplasty is an integral component to the complicated treatment of multiple myeloma, an incurable (yet treatable) cancer of the bone marrow that causes destructive lesions in bones and makes them more susceptible to fracture. By reducing pain and improving mobility, vertebroplasty helps patients become better equipped to continue with their rigorous treatment for multiple myeloma," said Eren Erdem, M.D., associate professor of radiology and neurosurgery and chief of interventional neuroradiology at the University of Arkansas for Medical Sciences in Little Rock. "There are many studies reporting the effectiveness of vertebroplasty in treating osteoporotic vertebral compression fractures. With 792 patients, this is the largest study to date in the treatment of compression fractures in multiple myeloma patients," he added.

"Vertebral compression fractures are very common in patients with multiple myeloma and cause severe pain and debilitation. Patients can experience compression of abdominal contents and a decrease in lung capacity, resulting in weight loss, anorexia and a reduced ability to perform normal daily functions," Erdem noted. "In our study, patients' pain from their spinal fractures was significantly reduced following vertebroplasty, resulting in about a 40 percent reduction in the use of narcotics for pain control," said Erdem, with half of the patients also reporting an improvement in their activity level following treatment.

About 20,000 Americans are diagnosed with multiple myeloma each year, making it the second most common blood cancer in the United States. Most patients are in their early sixties when diagnosed, and the disease is more common in men and African-Americans. Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. These cells are part of the immune system, which helps protect the body from germs and other harmful substances. In time, myeloma cells collect in the bone marrow and in the solid parts of bonecausing painful bone deterioration, typically in the drum-shaped bones of the spine, the vertebrae. Vertebral compression fractures occur when the internal scaffoldingbone marrowis weakened due to the cancer, explained the co-author of "Vertebral Augmentation in the Treatment of Non-osteoporotic Vertebral Compression Fractures in 792 Patients With Multiple Myeloma."

Researchers at the University of Arkansas for Medical Sciences treated 2,715 non-osteoporotic vertebral compression fractures in 792 patients with multiple myeloma (45 percent women; average age, 63) over a six-year period. Of 2,715 non-osteoporotic vertebral compression fractures, 2,258 were treated by vertebroplasty and 457 were treated by kyphoplasty, a procedure in which a balloon is placed in the vertebrae (then inflated) and bone cement is applied.

In the study, the average pain intensity score for patients based on the 11-point visual analog scale dropped significantly from 7.0 to 2.7. In the study, 37 percent of patients reported a decrease in medication usage; 62 percent had no change; and 1 percent reported an increase in medication usage. Also, 48 percent of patients reported an improvement in their post-procedural activity level, and 83 percent would consider vertebroplasty or kyphoplasty again, if needed.


Contact: Maryann Verrillo
Society of Interventional Radiology

Related medicine news :

1. California Institute of Integral Studies Launches Groundbreaking Community Mental Health Program
2. Deck of Cards is More Than a Game: Integral in Silverado Hospice Care
3. Environmental and Technology Firm Integral Consulting Inc. Expands Services, Launches New Website
4. OLC Memos Confirm Integral Role of Health Professionals in US Torture
5. Penn State plays integral role in $35 million stress project
6. Science and Engineering Firm Integral Consulting Inc. Announces Employee Promotions
7. Physician Assistants Integral to Care for Military Members and Their Families Coping With the Trauma of War
8. TELEHOUSE America Offers Integralis Data Loss Prevention Consulting Services as Part of its Manage-E Solution
9. Integralis Expert Resource Available to Discuss Twitter Denial of Service Attack and Web 2.0 Security
10. New Hires Signal Continued Expansion of Integral Consultings Geochemistry, Hydrogeology, and Mining Capabilities
11. Physical therapists play integral role in prevention, risk reduction, and treatment of lymphedema
Post Your Comments:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... While it’s ... poses a problem. Fortunately, an inventor from Austin, Texas, has identified a solution. , ... medication in darkness or restricted lighting. As such, it eliminates the need to turn ...
(Date:10/13/2017)... ... , ... Lori R. Somekh, founder of the Law Office of Somekh ... law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up ... network with elder law attorneys nationwide,” said Somekh. , ElderCounsel was ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th ... Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, ... The fun run is geared towards children of all ages; it is a non-competitive, ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the ... “America On The Brink” is the creation of published author, William Nowers. Captain ... As a WWII veteran, he spent thirty years in the Navy. Following his ...
(Date:10/12/2017)... ... 2017 , ... IsoComforter, Inc. ( ), one of the ... new design of the shoulder pad. The shoulder pad provides optimal support and ... pain while using cold therapy. By utilizing ice and water that is circulated from ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... Texas , Oct. 11, 2017  Caris Life ... focused on fulfilling the promise of precision medicine, today ... has joined Caris, Precision Oncology Alliance™ (POA) as its ... cancer centers, the St. Jude Crosson Cancer Institute will ... advance the use of tumor profiling, making cancer treatment ...
(Date:10/11/2017)... CHICAGO , Oct. 11, 2017  Hill-Rom Holdings, ... its Aspen Surgical facility in Las Piedras, ... surgical scalpels and blades. ... confirmed that the facility sustained minor structural damage, temporary ... Hurricane Maria. Repairs have been completed, manufacturing operations have ...
(Date:10/10/2017)...   West Pharmaceutical Services, Inc. (NYSE: WST), ... administration, today shared the results of a study highlighting ... intradermal administration of polio vaccines. The study results were ... 2017 by Dr. Ondrej Mach , Clinical Trials ... (WHO), and recently published in the journal Vaccine. ...
Breaking Medicine Technology: