Navigation Links
Vascular simulation research reveals new mechanism that switches in disease
Date:5/7/2014

x movements between cells in the sprout, which actually drives the cell rearrangement and tip cell competition," says Bentley. The team also found that during cancer development and progression, there is a switch: the regulation of the adhesion between cells becomes more uniform so that there are clustered regions of cells in an all-active or all-inhibited shuffling state.

"When we let Simulant cells loose in a simple simulated tumor environment, their collective behavior changed dramatically," says Bentley. "The cells go through cyclic phases of adhesion and junctional movements now as a group, in which they all clamber to move at once or all remain still. In either case they are getting nowhere as overtaking requires differential movement of one cell compared to its neighbors. The disrupted rearrangement provides a new explanation for the enlarged blood vessels we see in pathologies, such as in mouse models of tumors or retinopathies."

This research approach offers useful new principles for studying basic and complex questions about health and disease. "We hope that our work provides an example that cell level theory can be made accessible and, when integrated with experimentation, can help us unravel the complexities and dynamics of living systems and disease," adds Bentley.


'/>"/>

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
2. Original research papers on acute cardiovascular care: ESC launches EHJ-ACVC
3. Is it time for regional cardiovascular emergency care systems across the US?
4. New guidelines deliver concise messages for implementing cardiovascular prevention
5. Meditation practice may decrease risk for cardiovascular disease in teens
6. Meditation practice may decrease risk for cardiovascular disease in teens
7. Elsevier, SVS announce 2013 launch of Journal of Vascular Surgery: Venous and Lymphatic Disorders
8. Guidelines Issued for When Docs Should Order Vascular Testing
9. Exercise program improved health of lung transplant patients and cut cardiovascular risk
10. Low steroid levels linked to increased risk of cardiovascular disease
11. FDA Approves SonixGPS Needle Guidance Technology for Vascular Access Procedures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2014)... Recently, SweetDressy.com, a well-known dress supplier and ... of 2014 Evening Dresses. All these fresh items are ... marketing manager, the special offer is valid until Dec. ... Sweetdressy.com has been working well in the fashion industry ... designs. Their new dresses may be the best products ...
(Date:11/24/2014)... CA (PRWEB) November 24, 2014 SafeHandles™ ... episode of Innovations with Ed Begley Jr, airing via ... was created to provide a passive, non-invasive, replaceable, and ... how SafeHandles™ incorporates custom-fit shrinkable sleeves and adhesives to ... , “At the core of SafeHandles is the ...
(Date:11/23/2014)... The clinical trial report, "Aspergillosis Global ... the Aspergillosis clinical trial scenario. This report provides ... trials on Aspergillosis. It includes an overview of ... per the site of trial conduction across the ... disease clinical trials by their phase, trial status, ...
(Date:11/23/2014)... Pro Ace Care, a renowned Vancouver hot ... be providing an 8 year warranty on its selected hot ... went up due to the impending winter season, it was ... the premium service that the company provides. As a result, ... John Wood and Bradford hot water tanks. , “Every ...
(Date:11/23/2014)... Dallas, TX (PRWEB) November 23, 2014 ... the market such as its significance, programs and ... globally and Chinese suppliers major market gamers in ... company information, item specifications, prospective, manufacturing value, and ... statistical research, the evaluation symbolizes the globally and ...
Breaking Medicine News(10 mins):Health News:SweetDressy.com Unveiled A New Selection Of Evening Dresses 2Health News:New Episode of Innovations TV Series to Feature SafeHandles™ 2Health News:Aspergillosis Pipeline and Clinical Trials Market (Compnies and Drugs) Review H2 2014 Report at ReportsnReports.com 2Health News:Aspergillosis Pipeline and Clinical Trials Market (Compnies and Drugs) Review H2 2014 Report at ReportsnReports.com 3Health News:Aspergillosis Pipeline and Clinical Trials Market (Compnies and Drugs) Review H2 2014 Report at ReportsnReports.com 4Health News:Pro Ace Care Now Gives 8 Year Guarantee on Selected Vancouver Hot Water Tanks 2Health News:Femoral Stems Industry 2014 Analysis & 2019 Forecasts for Global and Chinese Region in New Research Report at ReportsnReports.com 2Health News:Femoral Stems Industry 2014 Analysis & 2019 Forecasts for Global and Chinese Region in New Research Report at ReportsnReports.com 3Health News:Femoral Stems Industry 2014 Analysis & 2019 Forecasts for Global and Chinese Region in New Research Report at ReportsnReports.com 4
... Pro-lifers and "Truth Truck" to hold vigil at Casey,s home ... babies. , SCRANTON, Pa., Dec. 18 The following was ... Pennsylvania pro-lifers to hold vigil at Casey,s home; "A Vote ... Beginning this evening, December 18, pro-lifers from PA will hold ...
... New York, New YorkAn overwhelming majority88 percentof young adults ... Congress and the President to pass health reform legislation ... improve health care, according to a Commonwealth Fund survey ... July of 2009, found that nearly half45 percentor approximately ...
... behaviors, beyond anorexia, can affect women. Indeed, some 10 ... and attitudes according to new study from the Universit ... published in the International Journal of Eating Disorders. ... a professor at the Universit de Montral Department of ...
... issue of an aging-focused newsletter deals with two pressing ... reform from the perspective of older minority adults. ... Gerontological Society of America (GSA), the country,s largest interdisciplinary ... this issue was provided by sanofi-aventis. Based on ...
... system turns off antibodies that could block HIV, study finds ... identified the cause of a major hurdle in efforts to ... scientists found that the immune system can produce B cells ... virus that causes AIDS. But the immune system mistakenly perceives ...
... Dec. 18 On Jan. 1, 2010, a new century begins ... an invitation to the nation to experience Scouting like never before. ... of Roses Parade, with a float entitled: "Celebrating the Adventure, Continuing ... time for our organization," said Bob Mazzuca, Chief Scout Executive of ...
Cached Medicine News:Health News:New Commonwealth Fund survey of young adults finds wide majority support health reform 2Health News:New Commonwealth Fund survey of young adults finds wide majority support health reform 3Health News:Disordered eating may affect 10 to 15 percent of women 2Health News:Boy Scouts of America Launch 100th Year With Scouting Experience of a Lifetime 2Health News:Boy Scouts of America Launch 100th Year With Scouting Experience of a Lifetime 3
(Date:11/22/2014)... , Nov. 21, 2014  Particle Sciences, Inc ... has developed and manufactured a new innovative vaginal ... Research and Development arm of Exeltis Pharmaceuticals.  According ... Project Management at Particle Sciences, "This vaginal ring ... our material sciences and modeling expertise.  We are ...
(Date:11/21/2014)... and VIENNA, Va. , ... in-home care provider that operates in Southern ... leading provider of remote caregiving technology. Alta will be ... existing client receiving homecare services. Logo - ... technology is the key to providing the kind of ...
(Date:11/21/2014)... , Nov. 21, 2014  Heated dialogue in recent ... – from cancer treatments to Gilead,s new hepatitis C ... around the world questioning what it means to put ... And while drug pricing is one ... – from both a general business and ethical standpoint ...
Breaking Medicine Technology:Particle Sciences' Clinical Trial Supplies Group Manufactures Innovative Vaginal Ring 2Alta Home Care, Inc. and BeClose Partner to Enable Seniors to Remain in Their Homes Safely and Securely 2"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 2"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 3"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 4"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 5
... , SANTA MONICA, Calif., Jan. 11 Derycz Scientific (OTC ... of facilitating the flow of information from content publishers to enterprise ... January 10, 2010, on the website of DDN ( ... & CEO Peter Derycz, is titled "Speeding the Path to FDA ...
... , , , SEATTLE, Jan. 11 Cell Therapeutics, Inc. ... JP Morgan Healthcare Conference in San Francisco. The conference will be held ... on Thursday, January 14, 2010, 2:00 PM Pacific Time. The conference will ... The webcast can be accessed at www.celltherapeutics.com . , , ...
Cached Medicine Technology:Derycz Scientific Featured In DDN (Drug Discovery News) 2Derycz Scientific Featured In DDN (Drug Discovery News) 3Cell Therapeutics, Inc. (CTI) to Present at the 28th Annual JP Morgan Healthcare Conference 2
Colloidal Gold Conjugated, Protein A - 12 OD...
Polyester ribbon impregnated with conjugated Protein G - .13 OD per sq. cm....
Colloidal Gold Sol, 30 nm 12 - 15 OD, 1 ml, Gold Sol Nanoparticles - not boiled, not centrifuged...
... empowering alternative to bulky biometry devices that ... PalmScan AP2000 is the world's only battery-operated, ... on the market today. Each unit weighs ... to perform multiple functions, namely: auto data ...
Medicine Products: