Navigation Links
Vascular simulation research reveals new mechanism that switches in disease
Date:5/7/2014

BOSTON -- Blood vessel formation is critical to life and its manipulation is instrumental to a number of diseases. For more than 40 years, investigations into the structure and function of endothelial cells lining the blood vessels have revealed a complex tissue with complex functions, demonstrating that endothelial cells participate in all aspects of vascular homeostasis and pathological processes.

Today, important revelations regarding endothelial cell behavior are emerging from vascular simulation research, a blossoming interdisciplinary field that makes use of novel computational models to uncover the cellular processes and dynamic interactions that take place as arteries and veins are built.

Vascular simulation research is the focus of two recent papers coauthored by investigators in the Center for Vascular Biology Research (CVBR) at Beth Israel Deaconess Medical Center (BIDMC), one of which provides a novel explanation for the enlarged blood vessels that are seen in various pathologies, including tumors and retinopathies.

"Understanding how, when and why individual endothelial cells coordinate decisions to change shape in relation to dynamic tissue environment signals is key to understanding normal and abnormal blood vessel growth," says Katie Bentley, PhD, Group Leader of the Computational Biology Laboratory in the CVBR and Assistant Professor of Pathology at Harvard Medical School. "Such insights could, for example, prove valuable in the treatment of cancer, which relies on a constant supply of blood to support tumor growth and cancerous spread."

Adaptive systems research brings things into focus

Bentley's computational modeling derives from training in Adaptive Systems research, an interdisciplinary field aimed at elucidating the fundamental organizing principles of living systems through the combined use of simulation, robotics and experimental models. Her work focuses on the construction of simul
'/>"/>

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
2. Original research papers on acute cardiovascular care: ESC launches EHJ-ACVC
3. Is it time for regional cardiovascular emergency care systems across the US?
4. New guidelines deliver concise messages for implementing cardiovascular prevention
5. Meditation practice may decrease risk for cardiovascular disease in teens
6. Meditation practice may decrease risk for cardiovascular disease in teens
7. Elsevier, SVS announce 2013 launch of Journal of Vascular Surgery: Venous and Lymphatic Disorders
8. Guidelines Issued for When Docs Should Order Vascular Testing
9. Exercise program improved health of lung transplant patients and cut cardiovascular risk
10. Low steroid levels linked to increased risk of cardiovascular disease
11. FDA Approves SonixGPS Needle Guidance Technology for Vascular Access Procedures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2015)... Karen A. Daley, Ph.D. will address graduates ... Commencement ceremony on May 9, 2015 and will ... of her eminent career as a nurse, public health ... and senior staff nurse at Brigham and Women’s Hospital ... roles, including President of the American Nurses Association in ...
(Date:3/31/2015)... March 31, 2015 Medical DNA Labs, ... met all criteria for Laboratory Accreditation by COLA, a ... to laboratories that apply rigid standards of quality in ... proficiency testing, and pass a rigorous on-site laboratory survey. ... as a result of a long-term commitment to provide ...
(Date:3/31/2015)... On March 26, 2015, Vogue Magazine UK, ... Slope?” provides a look into the trend of young women ... laser treatments . The article suggests that celebrity endorsements (Beyoncé ... as Kim Kardashian and Kylie Jenner are the drivers behind ... as significant influences on the self-esteem of teenagers. (see: goo.gl/NmaB4q) ...
(Date:3/31/2015)... Plains, NJ (PRWEB) March 31, 2015 Dr. ... Spear Education Institute for Advanced Dental Education. Here, he ... hands-on workshop designed to create a greater predictability in cases ... on the etiologies of tooth wear, and the correlation to ... is also a Mentor at Spear Education. After the ...
(Date:3/31/2015)... Dr. Uzma Parvez is having a busy start to ... Grounds Presentations at St. Michael’s Medical Center for attending staff ... The event was attended by a large gathering of students, ... from the Grand Rounds. It was said that it ... while. , Ahead, Dr. Parvez has been invited to ...
Breaking Medicine News(10 mins):Health News:Rivier University to recognize nurse leader, educator and safety advocate at 80th Commencement on May 9th 2Health News:Rivier University to recognize nurse leader, educator and safety advocate at 80th Commencement on May 9th 3Health News:Local Medical DNA Labs, LLC. Recognized for Quality Laboratory Services 2Health News:Cosmetic Surgery: Does Social Media Pressure Young Girls to Get Botox and Fillers? 2Health News:The dentists at Upper Montclair Dental Associates are happy to announce exciting new happenings at their practice. 2Health News:NJ Top Docs Presents, Dr. Uzma Parvez of Total Pain Care 2
... Omnicell, Inc.,(Nasdaq: OMCL ), a leading provider of system ... 18 to discuss the,company,s third quarter financial results. What: ... When: October 18, 2007, 2:30 p.m. PDT, ... officer ...
... , ... CSPA "CSPA has not had an opportunity for a ... while we cannot,make any definitive comment on this specific study, ... on a correlation of,various data. This process does not necessarily ...
... differently to the sweet treat , , FRIDAY, Oct. 12 (HealthDay ... your body will. That,s the message from a small new ... system, attuning people to the food they prefer to chow ... fans reacted differently when they ate the candy, compared to ...
... products, a growing world,population expected to reach 6.8 ... of that population, will push anesthesia drug sales ... Anesthesia Drugs: Worldwide Markets, a,new report by Kalorama ... required anesthetic,administration worldwide in 2006, and Kalorama Information ...
... Oct. 12 Managing competitive,intelligence is about ... industry information as a source at the ... winning strategy to reach business-,specific goals. Strategy ... its Competitive Edge. Best Practices, LLC,s ...
... they had planned sidelined by a diagnosis of a ... with the diagnosis. Many individuals find,their lives can be ... life.", The fall issue of Lupus Foundation of ... with lupus who,transformed their lives following their diagnosis. The ...
Cached Medicine News:Health News:Omnicell Schedules Third Quarter Earnings Call 2Health News:Consumer Specialty Products Association Responds to European Study Investigating Spray Products and Asthma 2Health News:Chocolate Lovers May Be Hard-Wired That Way 2Health News:Anesthesia Drugs Market to Grow to $4.3 Billion by 2011 as Populations and Uses for Anesthesia Increase 2Health News:Turn Competitive Intelligence into a Competitive Edge 2Health News:Living Your Best Life: Adjusting Mind, Body and Spirit 2
(Date:3/31/2015)... -- Ariana Smith, a 17-year-old Taylor teen, became the first patient ... a part of the Detroit Medical Center (DMC), and the ... a revolutionary 3D printed heart model to aid heart specialists ... In November, 2014, Ariana,s mom Jacqueline Foster ... a test that checks for problems with the electrical activity ...
(Date:3/31/2015)... ALPHARETTA, Ga. , March 31, 2015   ... Health Care, today announced it was awarded a new ... line of face masks. Effective March 1, 2015, Halyard,s ... masks with SO SOFT* lining, will be available to ... as well as 15,000 ambulatory surgery centers, physician practices ...
(Date:3/31/2015)... VICTORIA, BC , March 31, 2015 /CNW/ - T-Bird ... company focused on developing premium quality medical marijuana products ... the Marihuana for Medical Purposes Regulations ( Canada ... has received notice from The Corporation of the District ... rezoning approval of the Company,s premises which now allows ...
Breaking Medicine Technology:Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 2Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 3Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 4Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 5Halyard Health Signs First GPO Contracts As Independent Company 2Halyard Health Signs First GPO Contracts As Independent Company 3T-Bird Pharma Inc. Announces Final Municipal Rezoning Approval 2T-Bird Pharma Inc. Announces Final Municipal Rezoning Approval 3
... 29, 2011 Professional and Trade Relations groups play ... to professional, payer and patient groups. However, today,s restrictive ... PTR activities - thus creating pressure on PTR groups ... optimize their impact.   Recognizing changing needs ...
... Centocor Ortho Biotech Products, L.P., today announced that ... for trabectedin for the treatment of women with recurrent ... U.S. Food and Drug Administration,s (FDA) recommendation that an ... The NDA was submitted to the FDA ...
Cached Medicine Technology:Professional Relations Excellence Outlined in New Best Practices, LLC Report 2Centocor Ortho Biotech Products, L.P. Voluntarily Withdraws NDA for Trabectedin 2
Ishihara test chart book for color blindness. 14 plate. A simple accurate method for discovering congenital color blindness....
10 plate suitable for children and the illiterate....
Accepted by leading authorities as a simple and accurate method for discovering congenital color blindness of two type total color blindness and red/green blindness. This book is used for children an...
Stainless steel disposable retinal MVR blade, 10 pcs / box....
Medicine Products: