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Varian, Inc. Offers New Products for the Rapid Purification of Synthetic Oligonucleotides.

LAKE FOREST, Calif., Oct. 31 /PRNewswire-FirstCall/ -- Varian, Inc. (Nasdaq: VARI) announced today two new TOP (Trityl-on Oligonucleotide Purification) products, TOP-DNA and TOP-RNA, for the purification of synthetic oligonucleotides (oligos).

Synthetic DNA and RNA oligos are used by life science researchers to study the functions of genes and proteins within cells. For oligos to work properly, salts and incomplete products need to be removed from the synthesis mixture. Both TOP products allow full length oligos to bind to the sorbent bed while salts, incomplete oligos and other impurities are washed away. Subsequent cleavage of the protective dimethoxytrityl ("trityl") groups releases the purified completed product. Purification and de-tritylation within the TOP cartridge results in higher yields and greater purity of synthesized product in less time than with alternative methods.

TOP-DNA is designed to purify both short and long DNA oligos using a common method. TOP-RNA is a complete solution that includes cartridges and proprietary buffers specifically for RNA oligos.

"TOP-DNA and TOP-RNA extend the TOP line of products," said Martin O'Donoghue, Senior Vice President, Scientific Instruments, Varian, Inc. "Varian's TOP products make it easier for the synthesizers of oligos to deliver more products to their customers in less time."

For more technical information about Varian's Biosolutions, please visit

Varian, Inc. is a leading worldwide supplier of scientific instruments and vacuum technologies for life science and industrial applications. The company provides complete solutions, including instruments, vacuum components, laboratory consumable supplies, software, training and support through its global distribution and support systems. Varian, Inc. employs approximately 3,900 people and operates manufacturing facilities in 13 locations in North America, Europe and Asia Pacific. Varian, Inc. had fiscal year 2007 sales of $921 million, and its common stock is traded on the NASDAQ Global Select Market under the symbol, "VARI." Further information is available on the company's Web site:

Varian and the Varian Logo are trademarks of Varian, Inc.

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Varian, Inc.


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