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Vanderbilt researchers pioneer an advanced sepsis detection and management system
Date:6/15/2009

ding bacteria are more likely to be drug-resistant strains.

According to a study conducted by the Emory University School of Medicine and the Centers for Disease Control in 2003, the incidence of sepsis increased by an average of 8.7 percent a year over the prior 22 years. Today, sepsis treatment accounts for 40 percent of all ICU costs more than $17 billion annually, according to a 2001 study.

In 2006, Miller came to Vanderbilt from the Department of Homeland Security with the mission of fostering "the revolutionary transformation of healthcare" by the application of informatics technologies. "For a while, we were a solution looking for a problem," Miller recalled. In consultation with Gordon Bernard, the associate vice chancellor for research at VUMC, and with Associate Professor Arthur Wheeler and Assistant Professor Todd Rice in allergy, pulmonary and critical care medicine, Miller decided to focus on the problem of sepsis because it is common, deadly, expensive and treatable.

At the same time, ISIS computer scientists were investigating the issue of security and privacy of electronic patient records under the aegis of the National Science Foundation's TRUST (Team for Research in Ubiquitous Secure Technology) Science and Technology Center. When Miller and ISIS Director Janos Sztipanovits compared notes, they realized that ISIS had developed computer-modeling tools that could be used in the new project and that the project was compatible with TRUST's mandate.

Two years ago, Miller assembled his team. The clinical members were Martin; Liza Weavind, associate professor of anesthesiology; and David Maron, associate professor of medicine and emergency medicine. The informatics experts included Ed Shultz, director of information technology integration, and health system engineer Daniel Albert. Joining them from ISIS were Sztipanovits, senior research scientist Akos Ledeczi and graduate student Janos Mathe.

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Contact: David F. Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert  

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