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Vanderbilt nets brain gene research center
Date:10/2/2007

er proteins or have had selective changes to their serotonin signaling molecules.

We know that serotonin networks broadly, all the genes that cooperate to control serotonin assembly and signaling can be identified and manipulated in the mouse, Blakely said, and we feel strongly that the conservation of these networks in humans will allow us to formulate new hypotheses regarding disease-associated genetic variation.

The Conte Center will also support multiple core facilities that rest upon the significant technological framework that has been established at Vanderbilt through its shared resources program, Blakely added.

In addition to its core facilities that will benefit the wider Vanderbilt research community, the Conte Center will administer a pilot grant program targeted to young investigators or established investigators who wish to enter the field of serotonin biology. The center will also host an annual symposium centered on the themes of the Conte program, and Conte Center members will participate in outreach activities that convey to a broader audience the why behind the research.

Vanderbilt Conte Center projects and leaders:

  • Evan Deneris, Ph.D., Case Western Reserve University, Genetic networks establishing serotonergic neuronal identity
  • Pat Levitt, Ph.D., Vanderbilt, Serotonin modulation of axon guidance during brain development
  • Randy Blakely, Ph.D., Vanderbilt, Signaling networks sustaining serotonin transport
  • Elaine Sanders-Bush, Ph.D., Vanderbilt, Genetic variation of murine serotonergic phenotypes
  • Ronald Emeson, Ph.D., Vanderbilt, Modulation and function of serotonin-2C receptors
  • Douglas McMahon, Ph.D., Vanderbilt, Interactions of serotonin and circadian signaling networks


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Contact: Leigh MacMillan
leigh.macmillan@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center
Source:Eurekalert

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