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Van Andel Institute researchers find gene that could lead to new therapies for bone marrow disease
Date:9/28/2009

lls in the bone marrow don't create enough blood cells, and many of the blood cells they do create are abnormal. The body destroys the abnormal blood cells, resulting in low blood counts that can lead to fatigue, impaired immunity, easy bruising and bleeding, and other symptoms. According to the American Cancer Society, 80 to 90 % of all patients with MDS are older than 60 years. In about one third of patients, MDS turns into acute myeloid leukemia, a fast-growing bone marrow cancer.

Lead author of the study Aaron DeWard said that the genetic models that the lab is using are key to translating their discoveries into therapies. "The models allow us to identify and test novel therapeutics and ask more clinically relevant questions," said DeWard.


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Contact: Joe Gavan
616-234-5390
Van Andel Research Institute
Source:Eurekalert

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