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Valeant Pharmaceuticals Announces Preliminary Results From Its Phase IIa Retigabine Study for the Treatment of Postherpetic Neuralgia (PHN)
Date:8/24/2009

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About PHN

PHN is a painful complication of Herpes Zoster, a condition commonly known as "shingles." Shingles results from a reactivation of the Varicella Zoster virus, the same agent that causes chicken pox. Patients with shingles typically have a painful blistering rash that lasts for several weeks. PHN occurs when nerve fibers are damaged during an outbreak of shingles, causing chronic and often excruciating pain that may continue for months or years. Currently available treatments for PHN include topical medications, over-the-counter analgesics, tricyclic antidepressants and antiepileptics.

About Retigabine

Retigabine, a first-in-class neuronal potassium channel opener, is currently in late-stage development as an adjunctive treatment for patients with partial-onset seizures. In Phase III epilepsy trials, retigabine was shown to be efficacious with a demonstrated reduction in monthly seizure rates.

Retigabine Important Note

Retigabine has not been found by the Food and Drug Administration (FDA) or any other regulatory agency to be safe or effective in the diagnosis, mitigation, treatment or cure of any disease or illness. It may not be sold or promoted in the United States unless and until the FDA has approved a NDA. Similar restrictions apply in other countries.

The most common side effects associated with retigabine to date include somnolence, dizziness, confusion, speech disorder, vertigo, tremor, amnesia, abnormal thinking, abnormal gait, paresthesia, diplopia, incoordination, nervousness, abnormal vision, asthenia, headache, nausea and diarrhea.

About Valeant

Valeant Pharmaceuticals International (NYSE: VRX) is a multinational specialty pharmaceutical compan
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SOURCE Valeant Pharmaceuticals International
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