Navigation Links
Vaccines for Ovarian and Breast Cancer in Early Trials
Date:1/11/2008

Activating body's immune system should fight tumors, researchers say

FRIDAY, Jan. 11 (HealthDay News) -- Therapeutic vaccines to fight ovarian and breast cancer are in the first stage of clinical trials to determine their safety and effectiveness, researchers report.

The vaccine for ovarian cancer, developed by Dr. George Coukos, an assistant professor at the University of Pennsylvania's division of gynecologic oncology, is designed to "re-educate" the patient's immune system cells to destroy cancer cells.

"This trial is a phase I/II trial that is just getting started," Coukos said during a presentation Thursday evening at a meeting of the Alliance for Cancer Gene Therapy, in Greenwich, Conn. The trial will include some 30 women with ovarian cancer.

The vaccine makes use of the patients' own tumor cells, which are then put into the patients' own dendritic cells. Dendritic cells are responsible for initiating the body's immune response, Coukos said.

In this trial, two new drugs -- called DCVax-L and DCVax-L primed -- are being used to aid in growing new immune cells. The trial is also testing which of the drugs is most effective.

The "re-educated" dendritic cells are then injected back into the patient at intervals spanning as long as three years, according to Coukos. Once in the body, these cell are designed to attack the cancer cells.

Using this therapy in mice produced dramatic results, Coukos said. "Typically, the translation from mouse to human is always disappointing," he said. "We are hoping, based on other clinical data, there will be a good response."

By creating individualized ovarian cancer vaccines composed of a patient's own cells, Coukos believes that his tailored approach will be effective. "We actually use the patient's own tumor and the patient's own blood. So it's not one-type-of-therapy-fits-all. Everybody gets their own individualized treatment," he said.
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Human Papilloma Virus vaccines may decrease chances of oral cancer
2. CDC Study Links Thimerosal in Vaccines to Motor/Phonic Tics and Deficits in Attention, Behavior Control, Verbal IQ
3. Novartis Vaccines Launches National Gift-Giving Program to Help Protect Loved Ones by Reserving an Influenza Vaccination
4. Combination vaccines okay for infants, study shows
5. Colorado Influenza and Pneumococcal Alert Coalition (CIPAC) Partners with Novartis Vaccines for Holiday Vaccination Clinic, Making Influenza Vaccination Convenient for Shoppers
6. Novartis Vaccines Partners With RediClinic for Holiday Vaccination Clinic, Making Influenza Vaccination Convenient for Shoppers
7. Novartis Vaccines to Host Holiday Vaccination Clinic, Making Influenza Vaccination Convenient for Shoppers
8. St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases
9. Study Shows Cholera Can be Controlled With Oral Vaccines
10. Pneumococcal conjugate vaccines can improve the lives of HIV-infected children
11. New study suggests why vaccines directed against cancer, HIV dont work
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vaccines for Ovarian and Breast Cancer in Early Trials
(Date:7/31/2014)... July 31, 2014 Two Moms in ... three new products including: a Cacao Nib Nut Bar, Green ... Moms in the Raw products, each is 100% organic, gluten-free, ... is picky, so I’m constantly working on creating the best-tasting, ... healthy and tasty choices,” said Shari Leidich, Founder and VP ...
(Date:7/31/2014)... Shiitakes have been called “The workhorse of the ... Sauce below, they cook up in 5-10 minutes. They ... deep flavor -- four to ten times that of ... they're cooked with, so they add variety. They have ... are rich in fiber and contain a fat-absorbing compound ...
(Date:7/31/2014)... advocated in the United States, a new study suggests ... favorably, people share implicit hierarchies for racial, religious, and ... explicit attitudes and values. , The study findings appear ... Association for Psychological Science. , "People from relatively low-status ... have the most power. At the same time, ...
(Date:7/31/2014)... New Delhi, India (PRWEB) July 31, 2014 ... company, has launched a new service named ‘Remove Bad ... against which bad reviews are published on various review ... study about the world of internet marketing, the sites ... by its competitors in order to tailor the service. ...
(Date:7/31/2014)... The Beryl Institute announces three new members ... four new members of its Patient Experience Advisory ... community of practice and premier thought leader on improving ... members are industry leaders who advise on strategy, growth ... market and industry trends. The advisory board provides input ...
Breaking Medicine News(10 mins):Health News:Two Moms in the Raw Launches Three New, Raw, Sprouted 100% Organic Snacks 2Health News:Two Moms in the Raw Launches Three New, Raw, Sprouted 100% Organic Snacks 3Health News:Quick Fixin’ Summertime Meals with Shiitake Mushrooms -- Bring ‘em Home and Grow Your Own 2Health News:Quick Fixin’ Summertime Meals with Shiitake Mushrooms -- Bring ‘em Home and Grow Your Own 3Health News:Research reveals pervasive implicit hierarchies for race, religion, and age 2Health News:Reputation Management India Launches a New Service Called ‘Remove Bad Reviews’ 2Health News:The Beryl Institute Announces Seven New Patient Experience Board Members 2Health News:The Beryl Institute Announces Seven New Patient Experience Board Members 3
... first-ever genetic link to the reason African-Americans are at increased ... researchers at the University of Alabama at Birmingham (UAB) is ... testing. In the study, African-Americans with a Pro72 protein variant ... advanced form of colon cancer compared to whites, the researchers ...
... The Kroger Co. said today it is recalling Kroger Lite ... SEP-25-09 sold in Kroger stores in Southwestern Ohio, including Cincinnati and ... may be contaminated with Salmonella. No illnesses have been reported in ... , , , ...
... 31 LifeCare Holdings, Inc. (the "Company") today announced its ... 31, 2008. Three Months Ended December 31, ... patient service revenue of $94.2 million for the three months ... to the same period in 2007 while patient days were ...
... With the economy in a decline, many healthcare facilities are providing ... , ... (Vocus) March 31, 2009 -- Faced with ... money by relying on dependable professionally refurbished medical equipment ...
... Tenn., March 31 ProAssurance Corporation (NYSE: ... Podiatry Insurance Company of America (PICA) have overwhelmingly approved the ... into ProAssurance as a standalone subsidiary. ... domiciliary state of Illinois , is ...
... BSX ) announced today that the Court of ... Company,s stent litigation with Johnson and Johnson (J&J). The ... Bx Velocity and Cypher Stent Systems infringe Boston Scientific,s patent ... reversed the District Court with respect to the TAXUS Liberte ...
Cached Medicine News:Health News:LifeCare Holdings, Inc. Announces Year-End Results 2Health News:LifeCare Holdings, Inc. Announces Year-End Results 3Health News:LifeCare Holdings, Inc. Announces Year-End Results 4Health News:LifeCare Holdings, Inc. Announces Year-End Results 5Health News:LifeCare Holdings, Inc. Announces Year-End Results 6Health News:LifeCare Holdings, Inc. Announces Year-End Results 7Health News:LifeCare Holdings, Inc. Announces Year-End Results 8Health News:LifeCare Holdings, Inc. Announces Year-End Results 9Health News:LifeCare Holdings, Inc. Announces Year-End Results 10Health News:LifeCare Holdings, Inc. Announces Year-End Results 11Health News:LifeCare Holdings, Inc. Announces Year-End Results 12Health News:LifeCare Holdings, Inc. Announces Year-End Results 13Health News:LifeCare Holdings, Inc. Announces Year-End Results 14Health News:LifeCare Holdings, Inc. Announces Year-End Results 15Health News:Healthcare Facilities Focusing on Affordability, Dependability 2Health News:Healthcare Facilities Focusing on Affordability, Dependability 3Health News:PICA Policyholders Approve ProAssurance Transaction 2Health News:PICA Policyholders Approve ProAssurance Transaction 3Health News:PICA Policyholders Approve ProAssurance Transaction 4Health News:PICA Policyholders Approve ProAssurance Transaction 5Health News:PICA Policyholders Approve ProAssurance Transaction 6Health News:Appeals Court Affirms That J&J Stents Infringe Boston Scientific Patent; Claims Against TAXUS Liberte Dismissed 2Health News:Appeals Court Affirms That J&J Stents Infringe Boston Scientific Patent; Claims Against TAXUS Liberte Dismissed 3
(Date:7/31/2014)... July 31, 2014  Zacks.com announces the list of stocks ... Research analysts discuss the latest news and events impacting stocks ... include the Biogen (Nasdaq: BIIB - Free Report ), Gilead ... PBYI - Free Report ), AbbVie (NYSE: ABBV ... Free Report ). Today, Zacks is promoting its ...
(Date:7/31/2014)... YORK , July 31, 2014 TB ... better, faster and affordable treatments for tuberculosis (TB), announced ... Vice President, Market Access. Ms. Robertson joins the organization ... company,s business in Sub-Saharan Africa and Eastern ... oversee the TB Alliance,s efforts to ensure beneficial new ...
(Date:7/31/2014)... und KISSING, Deutschland, 31. Juli ... und Distributor eines computerunterstützten („robotischen") Koloskopie-Systems für ... (Homi) Shamir , ein weltweit anerkannter Manager ... und Kontrollgremiums zum Unternehmen stößt. ... Shamir ist ein hochangesehener globaler Visionär ...
Breaking Medicine Technology:The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 2The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 3The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 4The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 5The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 6TB Alliance Names Elana Robertson Senior Vice President, Market Access 2TB Alliance Names Elana Robertson Senior Vice President, Market Access 3invendo medical holt Nachum (Homi) Shamir in den Board of Directors des Unternehmens 2invendo medical holt Nachum (Homi) Shamir in den Board of Directors des Unternehmens 3
... 4, 2011 Bioness Inc. today ... of the FASTEST study to further examine the impact of ... drop as a result of stroke. The FASTEST study aims ... System over standard therapy with an ankle-foot orthosis (AFO), and ...
... Inc. (NASDAQ: NBIX ) today announced that it ... for elagolix and next-generation Gonadotropin Releasing Hormone (GnRH) Receptor Antagonists. ... with the FDA, the outcome of which generated a $20 ... event brings the total milestones achieved by the Company in ...
Cached Medicine Technology:Bioness Inc. Announces Completion of Enrollment in Its FASTEST L300 Study 2Neurocrine Biosciences Receives Second Milestone Payment of $20 Million Under Abbott Collaboration Agreement 2
... System is a long term, quality solution ... in both posterior stabilized and anatomically correct ... provides the flexibility needed to address patients' ... of identification keeps the user in mind ...
... Virtual Fluoroscopy software from ... has incorporated ease of ... features such as multiplanar ... models of image guided ...
... GE's surgical navigation ... first system to integrate ... tracking technology. It features ... fluoroscopic image to the ...
The ZEPHIR Anterior Cervical Plate System is the lowest profile plate clinically available....
Medicine Products: