Navigation Links
Vaccine to Prevent Heroin High Works in Animals
Date:7/28/2011

THURSDAY, July 28 (HealthDay News) -- Researchers say they're seeing promising results in animals from a vaccine designed to prevent a heroin high.

The vaccine produces antibodies -- a part of the immune system -- that appear to prevent heroin from reaching the brain and producing euphoria, the study authors explained.

"In my 25 years of making drug-of-abuse vaccines, I haven't seen such a strong immune response as I have with what we term a dynamic anti-heroin vaccine," principal investigator Kim D. Janda, a chair in chemistry at The Scripps Research Institute, said in an institute news release. "It is just extremely effective. The hope is that such a protective vaccine will be an effective therapeutic option for those trying to break their addiction to heroin."

Janda and his colleagues have already produced vaccines that try to stop the effects of cocaine and nicotine; they're being tested in humans. The new heroin vaccine targets both heroin and a chemical produced by its breakdown.

Addicted rats that were given the vaccine were also less likely to self-administer more heroin, in contrast to the ones that did not get the vaccine (the "control" rats). All of the control rats continued pressing levers to get more heroin, the investigators found.

Since heroin abuse and addiction also help drive the spread of HIV through needle sharing, the researchers are now exploring whether it might be possible to combine an HIV vaccine (none is currently available) and a heroin vaccine into the same injection.

The findings were released online in advance of print publication in the Journal of Medicinal Chemistry.

While the findings hold promise, experts note that research involving animals frequently fails to lead to benefits for humans.

More information

For more about drug abuse, visit the U.S. National L
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Aeras and China National Biotech Group sign memorandum of understanding for TB vaccine R&D
2. Chickenpox Vaccine May Wipe Out Related Deaths: Study
3. BIDMC to co-lead NIH consortium for AIDS vaccine research in nonhuman primates
4. Successful lab tests on a potential vaccine for heroin addiction
5. FDA Unveils Flu Vaccines for 2011-12 Season
6. Researchers Closer to Developing Universal Meningitis B Vaccine
7. Antibody Finding Might Help in Search for HIV Vaccine
8. Lack of clarity about HPV vaccine and the need for cervical cancer screening
9. Trials of Type 1 Diabetes Vaccines Bring Mixed Results
10. Certain Cancer Drugs Dont Interfere With Flu Vaccine: Study
11. Patients treated with sunitinib and sorafenib respond to flu vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vaccine to Prevent Heroin High Works in Animals
(Date:7/24/2014)... July 24, 2014 The federal ... ) in the U.S. District Court, District ... for plaintiff medical information covered by the federal ... the July 16th Order, U.S. District Judge Douglas ... Fresenius Medical Care the right to receive HIPAA- ...
(Date:7/24/2014)... IL (PRWEB) July 24, 2014 In a ... infertility expert and founder of Lotus Blossom Consulting LLC ... Rosato entitled Three Ways to Cut the High Cost ... way to minimize costs is to maximize your chance of ... advice on choosing a clinic. , “I am always ...
(Date:7/24/2014)... of Association Executives (ASAE) announced its 2014 Power of ... American Society of Anesthesiologists (ASA). , The ASA ... A Gold Award, one of the top honors from ... of the world through education on the global anesthesia ... care. , ASA was also honored with a Power ...
(Date:7/24/2014)... Kathleen Doheny HealthDay Reporter ... children often don,t view their kids as unhealthy or recognize ... a new study. The children of the families surveyed ... the Hasbro Children,s Hospital in Providence, R.I. "A third ... study researcher Dr. Kyung Rhee, now an assistant professor of ...
(Date:7/24/2014)... Pools and beaches are the place to ... dangerous, especially for small children, so Amica Insurance ... to the Centers for Disease Control and Prevention, children between ... for water-related injuries and deaths. It’s important to know the ... Amica is offering the following tips from the American Red ...
Breaking Medicine News(10 mins):Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 4Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 2Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 3Health News:Parents of Obese Kids Often View Them as Healthy 2Health News:Parents of Obese Kids Often View Them as Healthy 3Health News:Keep Kids Safe in the Water with 5 Tips from Amica 2
... , MONDAY, Aug. 29 (HealthDay News) -- Kids who ... preschoolers to grow into adults who lack self-control, a ... there are some individuals who consistently presented as high ... cognitive neuroscientist at the Sackler Institute for Developmental Psychobiology ...
... of improved management at the acute stage, the risk ... decreased by about 50% in the past 10 years. ... hospital, has resulted in improved survival and fewer recurrent ... try and further decrease long-term mortality in patients who ...
... 30, 2011] Vaccinating infants against rotavirus also prevents serious disease ... by the Centers for Disease Control and Prevention (CDC). This ... results of the study are published in The Journal ... . Rotavirus is a major cause of severe diarrhea ...
... HealthDay Reporter , MONDAY, Aug. 29 (HealthDay News) -- ... and Armageddon. Current events have left adults reeling as ... the last with no relent and no apparent end in ... kids who are worriers, they see this stuff is everywhere," ...
... , MONDAY, Aug. 29 (HealthDay News) -- ... be hazardous business, a new study shows. It found ... of being hit at crosswalks, and listening to music is ... environment lab that simulated cars moving in multiple directions, more ...
... multidisciplinary educational programme in cardiovascular prevention directed to ... cardiovascular risk. Cardiovascular prevention could have more success ... in the whole family, "said investigator Luciana Fornari, ... inspiration for this study, presented today at the ...
Cached Medicine News:Health News:'Gimme' Kids Often Grow Into 'Gimme' Adults 2Health News:'Gimme' Kids Often Grow Into 'Gimme' Adults 3Health News:What do patients receiving optimal medical therapy after a heart attack die from? 2Health News:Rotavirus vaccination of infants also protects unvaccinated older children and adults 2Health News:For Kids, Natural Disasters Can Whip Up Worries 2Health News:For Kids, Natural Disasters Can Whip Up Worries 3Health News:Mobile Devices Dangerous for Pedestrians, Too 2Health News:How a cardiovascular prevention program in a Brazilian school reduced parent's CVD risk 2
(Date:7/24/2014)... , July 24, 2014 LSI Medience ... an Agreement with Kineticos, a Raleigh-Durham, ... Kineticos will support LSI Medience in identifying opportunities ... to demonstrate utility in clinical trials. ... utility in diagnosis of sepsis, prognosis of septic ...
(Date:7/24/2014)...  The American Association for Homecare (AAHomecare) yesterday ... help address audit issues in the HME industry ... the information technology lead in shaping its HME ... billing and business management solutions for nearly 3,000 ... support this important initiative on behalf of all ...
(Date:7/24/2014)... 24, 2014 Decision Resources Group finds that, ... countries ( France , Germany ... Spain and the United Kingdom ... first once-daily long-acting beta2 agonist/inhaled corticosteroid (LABA/ICS) fixed-dose combination ... Relvar as a first-line LABA/ICS FDC in the treatment ...
Breaking Medicine Technology:LSI Medience Corporation and Kineticos Sign Agreement Related to the Presepsin Biomarker in Sepsis Management and Treatment 2Brightree Joins AAHomecare as Corporate Partner and IT Lead on HME Audit Key 2Surveyed EU5 Pulmonologists Expect that Relvar, the First Once-Daily LABA/ICS FDC, Will Experience Healthy Uptake in Asthma 2Surveyed EU5 Pulmonologists Expect that Relvar, the First Once-Daily LABA/ICS FDC, Will Experience Healthy Uptake in Asthma 3
... Shire plc (LSE: SHP, NASDAQ: SHPGY ... on the approval status and availability of ProAmatine® (midodrine ... orthostatic hypotension (SOH).  Shire has engaged in consistent dialogue ... the past 12 months in the hopes of either ...
... 22, 2011 PediaVision, maker of the new Spot vision ... upgrading their PediaVision screening units to the new Spot vision ... into the Lions Clubs on-going screening program. Dr. Hauser Weiler, ... the Lions Clubs in 1987.  He has dedicated himself to ...
Cached Medicine Technology:Shire Provides Update on ProAmatine® (midodrine HCl) 2Shire Provides Update on ProAmatine® (midodrine HCl) 3Shire Provides Update on ProAmatine® (midodrine HCl) 4Lions Clubs of Virginia Acquire 8 New Spot Vision Screeners 2Lions Clubs of Virginia Acquire 8 New Spot Vision Screeners 3Lions Clubs of Virginia Acquire 8 New Spot Vision Screeners 4
Sera available in three levels for the control of accuracy and precision for up to 31 analytes...
Human based material available in two levels for the control of accuracy and precision for upto 23 analytes....
CRP Liquid Conrtols level 3...
The GLU method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of glucose in serum, plasma, urine and cerebrospinal fluid....
Medicine Products: