Navigation Links
Vaccine to Prevent Heroin High Works in Animals
Date:7/28/2011

THURSDAY, July 28 (HealthDay News) -- Researchers say they're seeing promising results in animals from a vaccine designed to prevent a heroin high.

The vaccine produces antibodies -- a part of the immune system -- that appear to prevent heroin from reaching the brain and producing euphoria, the study authors explained.

"In my 25 years of making drug-of-abuse vaccines, I haven't seen such a strong immune response as I have with what we term a dynamic anti-heroin vaccine," principal investigator Kim D. Janda, a chair in chemistry at The Scripps Research Institute, said in an institute news release. "It is just extremely effective. The hope is that such a protective vaccine will be an effective therapeutic option for those trying to break their addiction to heroin."

Janda and his colleagues have already produced vaccines that try to stop the effects of cocaine and nicotine; they're being tested in humans. The new heroin vaccine targets both heroin and a chemical produced by its breakdown.

Addicted rats that were given the vaccine were also less likely to self-administer more heroin, in contrast to the ones that did not get the vaccine (the "control" rats). All of the control rats continued pressing levers to get more heroin, the investigators found.

Since heroin abuse and addiction also help drive the spread of HIV through needle sharing, the researchers are now exploring whether it might be possible to combine an HIV vaccine (none is currently available) and a heroin vaccine into the same injection.

The findings were released online in advance of print publication in the Journal of Medicinal Chemistry.

While the findings hold promise, experts note that research involving animals frequently fails to lead to benefits for humans.

More information

For more about drug abuse, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCE: The Scripps Research Institute, news release, July 20, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Aeras and China National Biotech Group sign memorandum of understanding for TB vaccine R&D
2. Chickenpox Vaccine May Wipe Out Related Deaths: Study
3. BIDMC to co-lead NIH consortium for AIDS vaccine research in nonhuman primates
4. Successful lab tests on a potential vaccine for heroin addiction
5. FDA Unveils Flu Vaccines for 2011-12 Season
6. Researchers Closer to Developing Universal Meningitis B Vaccine
7. Antibody Finding Might Help in Search for HIV Vaccine
8. Lack of clarity about HPV vaccine and the need for cervical cancer screening
9. Trials of Type 1 Diabetes Vaccines Bring Mixed Results
10. Certain Cancer Drugs Dont Interfere With Flu Vaccine: Study
11. Patients treated with sunitinib and sorafenib respond to flu vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vaccine to Prevent Heroin High Works in Animals
(Date:7/24/2017)... ... July 24, 2017 , ... The Topricin Companies, ... awareness for Topricin’s revolutionary, natural, after-burn skin care product, Topricin After Burn Cream. ... of long term skin conditions, including cancer. In the short term, overexposure ...
(Date:7/24/2017)... ... 24, 2017 , ... A CDC study shows that, although people are taking more steps to ... 29), had at least one case of sunburn within the past year. It’s common and ... ignore the issue. However, only recently have people become conscientious of the risks that accompany ...
(Date:7/24/2017)... ... 2017 , ... Anyone who uses scales know they have limits; a small ... that same scale to dispense medication. The first example is an issue of capacity, ... it is important to have the right balance for the process. METTLER TOLEDO’s new ...
(Date:7/24/2017)... OR (PRWEB) , ... July 24, 2017 , ... Sharon ... Climate Change and Your Health on VoiceAmerica sponsored by Nature’s Tears® EyeMist® recently talked ... the rise of myopia in China. , The article by Zidor Aldama described the ...
(Date:7/24/2017)... ... July 24, 2017 , ... Paul Vitenas, MD, FACS is excited to report ... invited to attend Allergan’s recent meeting with their Plastics Advisory Board. As one of ... Allergan is bringing a newly defined structure to the aesthetics market. Dr. Vitenas ...
Breaking Medicine News(10 mins):
(Date:7/11/2017)... , July 11, 2017  Sysmex America, ... urinalysis diagnostic testing equipment as well as middleware ... a way to make quality assurance easier and ... "Sysmex is well known for the innovation that ... Quality Monitor elevates quality assurance processes to a ...
(Date:7/10/2017)... , July 10, 2017  BDI Group subsidiary ... patient support services organization serving specialty pharmacies, home ... launch of four significant, value-added member programs designed ... better manage reimbursement and improve access and affordability ... therapies. ...
(Date:7/5/2017)... Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ) ... company focused on the development of oral drug delivery systems, ... Securities Authority to dual-list its common stock on the Tel ... on the TASE on July 12, 2017 under the ticker ... it is expected that Oramed will be included in the ...
Breaking Medicine Technology: