Navigation Links
Vaccine to Prevent Heroin High Works in Animals
Date:7/28/2011

THURSDAY, July 28 (HealthDay News) -- Researchers say they're seeing promising results in animals from a vaccine designed to prevent a heroin high.

The vaccine produces antibodies -- a part of the immune system -- that appear to prevent heroin from reaching the brain and producing euphoria, the study authors explained.

"In my 25 years of making drug-of-abuse vaccines, I haven't seen such a strong immune response as I have with what we term a dynamic anti-heroin vaccine," principal investigator Kim D. Janda, a chair in chemistry at The Scripps Research Institute, said in an institute news release. "It is just extremely effective. The hope is that such a protective vaccine will be an effective therapeutic option for those trying to break their addiction to heroin."

Janda and his colleagues have already produced vaccines that try to stop the effects of cocaine and nicotine; they're being tested in humans. The new heroin vaccine targets both heroin and a chemical produced by its breakdown.

Addicted rats that were given the vaccine were also less likely to self-administer more heroin, in contrast to the ones that did not get the vaccine (the "control" rats). All of the control rats continued pressing levers to get more heroin, the investigators found.

Since heroin abuse and addiction also help drive the spread of HIV through needle sharing, the researchers are now exploring whether it might be possible to combine an HIV vaccine (none is currently available) and a heroin vaccine into the same injection.

The findings were released online in advance of print publication in the Journal of Medicinal Chemistry.

While the findings hold promise, experts note that research involving animals frequently fails to lead to benefits for humans.

More information

For more about drug abuse, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCE: The Scripps Research Institute, news release, July 20, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Aeras and China National Biotech Group sign memorandum of understanding for TB vaccine R&D
2. Chickenpox Vaccine May Wipe Out Related Deaths: Study
3. BIDMC to co-lead NIH consortium for AIDS vaccine research in nonhuman primates
4. Successful lab tests on a potential vaccine for heroin addiction
5. FDA Unveils Flu Vaccines for 2011-12 Season
6. Researchers Closer to Developing Universal Meningitis B Vaccine
7. Antibody Finding Might Help in Search for HIV Vaccine
8. Lack of clarity about HPV vaccine and the need for cervical cancer screening
9. Trials of Type 1 Diabetes Vaccines Bring Mixed Results
10. Certain Cancer Drugs Dont Interfere With Flu Vaccine: Study
11. Patients treated with sunitinib and sorafenib respond to flu vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vaccine to Prevent Heroin High Works in Animals
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that ... insurance companies have a waiver for care if the client has a cognitive impairment ... family pays for care, is often waived, so the benefits from their insurance start ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed ... consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has ... highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information ... we intend to develop to enable prevention of a major side effect of ... loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... R.I. , Sept. 25, 2017  EpiVax, ... assessment, vaccine design, and immune-engineering today announced the ... on the development of personalized therapeutic cancer vaccines. ... has provided exclusive access to enabling technologies to ... Eng., MBA will lead EpiVax Oncology as Chief ...
(Date:9/19/2017)... 19, 2017   ZirMed Inc ., a recognized leader ... that it has been ranked #1 by its users for ... Rankings 2017 User Survey. ZirMed was recognized as the top-ranked ... and medical centers over 200 beds and holds one of ... user survey history. ...
(Date:9/12/2017)... MOUNTAIN LAKES, N.J. , Sept. 12, 2017  Consumer reviews ... Embrace Hearing as the number one company for hearing ... Oticon™, ReSound™ and fifteen other brands. ... Embrace Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that ...
Breaking Medicine Technology: