Navigation Links
Vaccine for Asbestos-Related Cancer Looks Safe
Date:3/4/2010

In tests, novel immunotherapy appears to combat mesothelioma tumors

THURSDAY, March 4 (HealthDay News) -- An investigational vaccine for the asbestos-related cancer mesothelioma is safe, according to a new study.

Researchers in the Netherlands tested the vaccine -- which infuses a patient's own dendritic cells with antigen from the patient's tumor -- on 10 patients and found that it induced an immune T-cell response against mesothelioma tumors.

This is the first time DC-based immunotherapy has been tested in patients with mesothelioma, which typically occurs in the lungs but can arise at other body sites. The study was published online March 4 in advance of an upcoming print issue of the American Journal of Respiratory and Critical Care Medicine.

Asbestos has been banned in developed countries for decades, but the incidence of mesothelioma is expected to continue to increase until 2020. Median survival after mesothelioma diagnosis is about 12 months. The standard chemotherapy treatment improves survival by about three months.

"The possibility to harness the potency and specificity of the immune system underlies the growing interest in cancer immunotherapy," study author Dr. Joachim Aerts, a pulmonary physician at Erasmus Medical Center, said in a news release. "One such approach uses the patient's own [dendritic cells] to present tumor-associated antigens and thereby generate tumor-specific immunity."

Dendritic cells are a form of immune system cell.

"The major problem in mesothelioma is that the immunosuppressive environment caused by the tumor will negatively influence our therapy so we are now working on a method to lower this immunosuppressive environment," Aerts said. "We hope that by further development of our method it will be possible to increase survival in patients with mesothelioma and eventually vaccinate persons who have been in contact with asbestos to prevent them from getting asbestos related diseases."

More information

The U.S. National Cancer Institute has more about mesothelioma.



-- Robert Preidt



SOURCE: American Thoracic Society, news release, March 4, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Groundbreaking research to find vaccine for hepatitis C
2. Possible vaccine for mesothelioma proven safe
3. The Coalition for Vaccine Safety Calls for Congressional Hearings on Federal Agencies Failure to Provide Adequate Safety Research
4. Texas-based consortium announces groundbreaking vaccine research program
5. New Technology Could Widen Reach of Vaccines
6. Screens, Vaccine for HPV Less Beneficial in Older Women
7. New strategy produces promising advance in cancer vaccines
8. Vaccine Not Fail-Safe in Ongoing Mumps Outbreak
9. Vaccine May Prevent TB in People With HIV
10. Mimotopes Awarded Major Peptide Supply Contract by the Queensland Institute of Medical Research in the Search for an Effective Malaria Vaccine
11. UM School of Medicine scientists find new malaria vaccine is safe and promotes immune response in children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... certification process to promote standards of excellence for the field of eating disorders, ... March 22 – 25, 2018 in Orlando, Florida at the Omni Resort at ...
(Date:10/13/2017)... LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for care ... is the 90-day elimination period, when the family pays for care, is often waived, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, ... lowdown on sciatica in a new episode of "Success Files," which is an ... and innovation and investigates each subject in-depth with passion and integrity. , Sciatica ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San Francisco ... using cutting-edge Oventus O2Vent technology. As many as 18 million Americans are estimated ... in breathing. Oral appliances can offer significant relief to about 75 percent of ...
(Date:10/12/2017)... ... , ... Asante, a nationally recognized health system in southern ... home health joint venture through an agreement, effective October 1, 2017, to create ... health company with Asante, delivering clinically integrated care, for the past eight years. ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)... COPENHAGEN, Denmark , Oct. 2, 2017 The ... tool in the struggle to reverse the tide of prescription ... plan for regulating their medicine intake and stepping down their ... is set to launch in December 2017; the first 100,000 ... access. Learn more at http://www.rebound-solution.com/ ...
(Date:9/25/2017)... --  Montrium , an industry leader in powerful ... Trial Master Files & Inspection Readiness Conference ( ... Services has selected eTMF Connect to ... a leading European contract research organization (CRO), will ... enable greater collaboration with sponsors, improve compliance and ...
Breaking Medicine Technology: