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Vaccine and drug research aimed at ticks and mosquitoes to prevent disease transmission
Date:12/2/2008

sing mild to severe anemia and often death. "Even if the cow doesn't die," explains Professor Kocan, "the bacteria serve as a continued source of infection for cows and ticks. We are working on a vaccine to target tick-protective genes, so when ticks feed on immunized cattle, the vaccine antibodies interfere directly with the biology of the tick and its feeding pattern which results in reduced tick populations." The vaccine model being developed for cattle, which we call a dual target vaccine approach because both ticks and tick-borne pathogens are targeted, will likely be applicable to other ticks and the bacteria that they transmit.

According to Professor Foy, this theory of vaccine and drug development would offer many advantages over currently-used mosquito and tick-borne disease control measures: it would be more targeted than environmental spraying of insecticides; proper application would kill older frequently-biting insects and interrupt disease transmission; resistance would be slower to develop; and there may be little cross-resistance from agricultural applications.


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Contact: Jennifer Bender
jbender@environics-usa.com
203-325-8772
American Society of Tropical Medicine and Hygiene
Source:Eurekalert

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