Navigation Links
Vaccine Stops Tumor Spread in Mice
Date:4/18/2010

Treatment may be used one day as part of cancer-fighting arsenal, but more study is needed

SUNDAY, April 18 (HealthDay News) -- A new study in mice suggests that a transcription factor normally found in male germ cells could become a target for cancer vaccines.

A transcription factor is a protein that controls the transfer (or transcription) of genetic material from the DNA to messenger RNA. This particular factor, known as Brother of the Regulator of Imprinted Sites (BORIS), promotes tumor growth.

Scientists were able to develop a vaccine from BORIS that was effective in helping stop the spread of a breast cancer-like tumor to other parts of the body, a process known as metastasis.

The vaccine "is capable of inducing strong and effective antitumor immunity, but the efficacy of this [strategy] could be even better if one could eliminate immune suppressor cells," lead researcher Michael G. Agadjanyan, head of the department of immunology and professor at the University of California, Irvine's Institute for Molecular Medicine, said in a press release.

Researchers tested the value of a mutated virus using the factor on mice with a form of cancer similar to breast cancer found in humans. They delivered the vaccine into the body by using immune cells known as dendritic cells, whose treelike branches form connections with other cells in the body.

The factor delivered by dendritic cells "elicited strong antitumor cellular immune responses in tumor-free mice," Agadjanyan said. "More importantly, therapeutic vaccination dramatically inhibited both tumor growth and the number of metastases in the lungs of tumor-bearing mice."

He cautioned, however, that the BORIS-based vaccine did not entirely eliminate tumors or stop the spread of cancer. For that reason, it should be combined with other strategies that enlist the immune system to combat cancer, he said.

The study findings were sc
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Guillain-Barre Syndrome Very Rare After H1N1 Vaccine
2. Flu Vaccine With Both B Strains May Offer Better Protection
3. Vaccine Reverses Type 1 Diabetes in Mice
4. Clinical trial to test whether vaccine can effectively treat melanoma
5. Building a better flu vaccine: Add second strain of influenza B
6. Oral Vaccine May Help People With COPD
7. Genetic Engineering Raises Hope for Lyme Disease Vaccine
8. Only 1 in 4 Americans Got H1N1 Vaccine
9. Clues Found to How Different Flu Vaccines Work
10. GSK Joins Global Vaccine Alliance to Help Prevent Millions of Children from Contracting Pneumococcal Disease in the Worlds Poorest Countries
11. Miles for Hope’s Moving Towards A Cure(SM) Brain Tumor Walk in Boston Raising Funds for Brain Tumor Vaccine and Massachusetts General Hospital
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/3/2015)... EMBARGOED FOR RELEASE UNTIL 2 P.M. ET, WEDNESDAY, ... of Mother’s Home to Gas Wells , PITTSBURGH, June 3, ... of natural gas wells drilled with hydraulic fracturing were more ... living farther from such wells, according to a University ... southwestern Pennsylvania birth records. , The finding does not ...
(Date:6/3/2015)... York, NY (PRWEB) June 03, 2015 ... agreed to pay $7.8 million to resolve a Risperdal ... Arkansas over tactics the company allegedly used to market ... County Circuit Court indicate that the Arkansas Attorney General ... part of the accord. The Risperdal settlement amounts to ...
(Date:6/3/2015)... 2015 Follow us on LinkedIn ... revolutionized disease treatment on account of their better mode ... such as rheumatoid arthritis. The industry is expected to ... small molecule drugs to biopharmaceuticals over the coming years. ... and gene therapies, and recombinant proteins has attracted industry ...
(Date:6/3/2015)... (PRWEB) June 03, 2015 Dr. Steven Reisman, ... Cardiac Diagnostic Center ( http://www.newyorkcardiac.com ) located in NYC, announced ... weekdays to his practice. In most cases, depending on the ... the day they call, they will be seen by a ... priority as a cardiologist is to ensure that people who ...
(Date:6/3/2015)... York, NY (PRWEB) June 03, 2015 ... strategic partnership to expand online and mobile access ... Board Review and Maintenance of Certification (MOC) activities. ... will market VeoMed’s innovative courses to Decker’s extensive ... professionals interested in purchasing access to VeoMed’s premier ...
Breaking Medicine News(10 mins):Health News:Fracking Proximity Associated with Lower Birth Weight 2Health News:Fracking Proximity Associated with Lower Birth Weight 3Health News:Fracking Proximity Associated with Lower Birth Weight 4Health News:Risperdal Lawsuit News: Johnson & Johnson, Janssen Settle Arkansas Marketing Case for $7.8 Million 2Health News:Risperdal Lawsuit News: Johnson & Johnson, Janssen Settle Arkansas Marketing Case for $7.8 Million 3Health News:Risperdal Lawsuit News: Johnson & Johnson, Janssen Settle Arkansas Marketing Case for $7.8 Million 4Health News:Superior Efficacy of Biopharmaceuticals Against Chronic Diseases Drives the Global Biopharmaceuticals Market, According to a New Report by Global Industry Analysts, Inc. 2Health News:Superior Efficacy of Biopharmaceuticals Against Chronic Diseases Drives the Global Biopharmaceuticals Market, According to a New Report by Global Industry Analysts, Inc. 3Health News:Superior Efficacy of Biopharmaceuticals Against Chronic Diseases Drives the Global Biopharmaceuticals Market, According to a New Report by Global Industry Analysts, Inc. 4Health News:NYC Cardiologist, Dr. Steven Reisman, Announces Same Day and Evening Appointments 2Health News:VeoMed and Decker Intellectual Properties, the Owner of Scientific American Medicine, Announce a Partnership to Expand Access to Premier Online CME Courses 2
... The Sanitizer, Game Allows Consumers to Zap Germs in the Water Just ... ... 20 Just in time for Memorial Day,integrated marketing communications agency, Fletcher ... BioGuard,s new UV sanitizing unit, BioLab UV ( http://www.biolabuv.com ). ...
... is a well known disease entity that has a wide ... the colonic blood supply is key to its development. However, ... causes ischemia of the bowel. This report describes the first ... and splenic veins. , This case report, from a ...
... not uncommon to find tissue that normally lines the stomach ... tissue has been identified in such diverse locations as the ... case, reported by a team led by Dr. Steven Paul ... the World Journal of Gastroenterology. , Typically, when this gastric ...
... no obvious effects on MKN-45 cells proliferation and apoptosis. At ... apoptosis improved. It may be that CO2 gas affected the ... by a team led by Professor Pei-Wu Yu. The research ... World Journal of Gastroenterology. , There is an ongoing debate ...
... and calm, according to a new study from the Population ... at about age 60, participants reported more feelings of ease ... John Mirowsky, professors of sociology, have published the findings in ... issue of Social Science and Medicine. The research was funded ...
... substantial financial income and the ... chance to change people,s lives, ... so,people are increasingly looking for new ways to make the ... Today, that,s,possible with the independent marketing opportunities provided by,Melaleuca, The ...
Cached Medicine News:Health News:Fletcher Martin Creates Interactive Game-Ad for BioLab(R) UV for BioGuard(R) 2Health News:Heterotopic gastric tissue simulating acute appendicitis 2Health News:With age comes a sense of peace and calm 2Health News:Lucrative Sales Opportunities Abound With Melaleuca, The Wellness Company(R) 2
(Date:6/3/2015)... 2015 According to a ... Vascular Devices Market (Embolic Protection, Chronic Total Occlusion, ... IVC Filters, Stents, Balloons and Accessories) - Forecasts ... and Peripheral Vascular Devices Market is expected to ... CAGR of 7.4% from 2014 to 2019. ...
(Date:6/3/2015)... -- Essential Medical, Inc., a privately held medical device company, ... at the 2015 Jefferies Global Healthcare Conference in ... The company will present on its ... first in human results on both the 14F and ... punctures made during cardiac catheterization procedures such as transcatheter ...
(Date:6/3/2015)... June 3, 2015 RXi Pharmaceuticals ... company focused on discovering and developing innovative ... and ophthalmology, today announced that it received a ... Patent and Trademark Office (USPTO) on its ... titled "RNA Interference in Ocular Indications," covers ...
Breaking Medicine Technology:The Interventional Cardiology and Peripheral Vascular Devices Market Worth $26.72 Billion by 2019 2The Interventional Cardiology and Peripheral Vascular Devices Market Worth $26.72 Billion by 2019 3The Interventional Cardiology and Peripheral Vascular Devices Market Worth $26.72 Billion by 2019 4Essential Medical Inc. Announces Participation in 2015 Jefferies Global Healthcare Conference - NYC 2RXi Pharmaceuticals Granted Notice of Allowance for Patent Covering Lead Compound, RXI-109, for Use in the Eye 2RXi Pharmaceuticals Granted Notice of Allowance for Patent Covering Lead Compound, RXI-109, for Use in the Eye 3RXi Pharmaceuticals Granted Notice of Allowance for Patent Covering Lead Compound, RXI-109, for Use in the Eye 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: