Navigation Links
Vaccine Stops Alzheimer's Brain 'Tangles'
Date:8/21/2007

In mouse study, it prevented buildup of dangerous tau protein

TUESDAY, Aug. 21 (HealthDay News) -- A vaccine designed to combat a protein implicated in Alzheimer's disease has proven effective in mice, U.S. scientists say.

Abnormal tau protein accumulates into damaging tangles in the memory center of the brains of Alzheimer's patients, noted a team at the New York University Medical Center (NYUMC).

However, the new NYUMC-developed vaccine prevented tau tangles in several regions of the central nervous system of mice that were genetically engineered to produce abnormal tau proteins.

The vaccine prompted the immune system to produce antibodies that could enter the brain and bind to abnormal tau, the researchers said. This prevented tau from forming harmful tangles and causing motor coordination problems in the mice.

The study, which is published in the Aug. 22 issue of the Journal of Neuroscience, is the first to show that a vaccine can induce the immune system to combat abnormal tau protein.

"This approach may have extensive therapeutic implications, because you can specifically target the problematic protein," team leader Einar Sigurdsson, assistant professor of psychiatry and pathology, said in a prepared statement.

"Tau aggregates are inside the cell, making it especially difficult to develop a therapy to target and clear them from the cell," Sigurdsson noted.

More information

The U.S. National Institute on Aging has more about Alzheimer's disease.



-- Robert Preidt



SOURCE: New York University Medical Center, news release, Aug. 22, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Vaccine to quit smoking?
2. First Vaccine Designed for Africa Cleared for Testing in Humans
3. New hope for cancer victims – will vaccine cure the deadly bug
4. Vaccine for Alzheimer’s diseas
5. New vaccine helps allergy and asthma patients
6. Man against HIV – new vaccine ready for human trials
7. New vaccine helps allergy and asthma patients
8. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
9. HIV did not arise from polio vaccine
10. Double impact vaccine
11. Health Officials Recommend Flu Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Pekin, IL (PRWEB) , ... October 13, 2017 ... ... Foundation, which established the certification process to promote standards of excellence for the ... iaedp™ Symposium, scheduled for March 22 – 25, 2018 in Orlando, Florida at ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton ... staged a mock evacuation of the facility as part of a disaster drill on ... Echo Hose EMS and Shelton City Emergency Manager, as well as the Connecticut ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run ... This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed ... geared towards children of all ages; it is a non-competitive, non-timed event, which is ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Planet Fitness, ... the U.S., announced today its plans to open a flagship location in Covington, LA ... the former Rooms To Go store next to Office Depot in the Holiday Square ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... , Oct. 2, 2017 Diplomat Pharmacy, Inc. ... Day Software and Consulting, LLC , and named its ... Software, based in Tennessee , will ... Day expands EnvoyHealth,s service offerings for health care partners ... "In an interoperable world, ...
(Date:10/2/2017)... Fla. , Oct. 2, 2017  AllianceRx Walgreens ... company formed by Walgreens and pharmacy benefit manager Prime ... its new brand, which included the unveiling of new ... , as well as at a few other ... the new brand to patients, some of whom will ...
(Date:10/2/2017)... Denmark , Oct. 2, 2017 The Rebound ... in the struggle to reverse the tide of prescription drug ... for regulating their medicine intake and stepping down their dosage ... set to launch in December 2017; the first 100,000 people ... Learn more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology: