Navigation Links
Vaccine Shows Some Promise Against Advanced Cancers
Date:8/2/2010

late the body's immune system.

In their work, the authors removed the innards of the virus and substituted instead a gene for the carcinoembryonic antigen (CEA). This immune system biomarker is overproduced in many different types of cancer.

The vaccine was then administered multiple times over a period of three months to 28 patients with advanced, recurrent forms of lung, colon, breast, appendix or pancreatic cancer. The participants had already failed several rounds of standard chemotherapy.

Five patients displayed a response to the therapy: Two who had already been in remission stayed in remission; two patients saw their cancers stabilize; and a liver lesion in one patient with pancreatic cancer was no longer evident.

The responses tended to occur in patients with smaller tumors and in those receiving higher doses of the vaccine.

The alphavirus-based vaccine also managed to evade the immune system's regulatory T cells, which could have shut down the body's immune response, the researchers said.

Although T cell levels were elevated in some patients, the vaccine was able to get around them.

Co-authors included employees from Alphavax, which develops new vaccine technology. The study was partially supported by the U.S. National Cancer Institute.

More Information

There's more on cancer vaccines at the U.S. National Cancer Institute.

SOURCES: Michael Morse, M.D., associate professor, medicine, Duke University Medical Center; Adam Cohen, M.D., assistant professor, medical oncology, Fox Chase Cancer Center, Philadelphia; Aug. 2, 2010, Journal of Clinical Investigation, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Vaccine May Prevent TB in People With HIV
2. Vaccine Not Fail-Safe in Ongoing Mumps Outbreak
3. New strategy produces promising advance in cancer vaccines
4. Screens, Vaccine for HPV Less Beneficial in Older Women
5. New Technology Could Widen Reach of Vaccines
6. Texas-based consortium announces groundbreaking vaccine research program
7. The Coalition for Vaccine Safety Calls for Congressional Hearings on Federal Agencies Failure to Provide Adequate Safety Research
8. Possible vaccine for mesothelioma proven safe
9. Groundbreaking research to find vaccine for hepatitis C
10. Vaccine for Asbestos-Related Cancer Looks Safe
11. CDC Awards Abt Associates Additional Contracts to Evaluate Effectiveness of H1N1 Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vaccine Shows Some Promise Against Advanced Cancers
(Date:7/31/2014)... 31, 2014 The 2013 edition ... about chemical listings, appellate decisions, litigation and settlement ... affect compliance with California's Proposition 65. , The ... law, regulations, history and trends impacting California's Proposition ... installment of the series which adds approximately 200 ...
(Date:7/31/2014)... (August 1, 2014) If you have asthma, you may ... to help you recognize and respond to changes and understand ... you,re in the green zone, you,re doing well, yellow means ... means you require urgent care. New guidelines are now available ... zone, back into green and away from the red zone. ...
(Date:7/31/2014)... Developer Jamestown, L.P., has been using ... City Market project in Atlanta’s Old Fourth Ward, which ... building into best-in-class office, housing, and retail spaces. As ... with their construction webcam service to assess how it ... construction camera for monitoring and documentation purposes, ...
(Date:7/31/2014)... Hoping to attract new customers who are ... , NutriGold is ready to ship out free samples of ... advantage of this offer fast and easy: http://www.nutrigold.com/Free-Samples ... at NutriGold, "We know that every time customers purchase one ... precious asset: their own health or the health of a ...
(Date:7/31/2014)... has announced that they are now offering a new ... Review of Sexual Satisfaction . The course is ... Clinical and Health Psychology. , This CE course has ... accurate information about sexual satisfaction so that healthcare professionals ... provides a systematic review of 197 research publications in ...
Breaking Medicine News(10 mins):Health News:Save 25% on the Proposition 65 Handbook - 2013 Edition Through August 31 2Health News:OxBlue Construction Webcam Proves Valuable Tool for Developer, Consumers on Historic Ponce City Market Project 2Health News:OxBlue Construction Webcam Proves Valuable Tool for Developer, Consumers on Historic Ponce City Market Project 3Health News:NutriGold Launches Product Samples Page for its Supplements 2Health News:NutriGold Launches Product Samples Page for its Supplements 3Health News:Company Provides New Course on Sexual Satisfaction 2Health News:Company Provides New Course on Sexual Satisfaction 3
... ... with GFK Custom Research North America, selected Warady & Davis LLP, Certified Public Accountants ... Chicago based on its innovative internships, "W&D University" training program, flexible scheduling, great team ... ...
... Oct. 28 The Board of Directors of Healthcare Trust ... of October, November, and December 2009. These distributions will ... during such month and will equal a 7.25% annualized rate ... The payment date for each of the daily distributions for ...
... , DENVER, Oct. 28 Many medical practices are ... are making basic business mistakes, according to Andrew Graham, ... the top reasons practices struggle, said Graham. , ... needs to include goals for revenue generation, customer service, ...
... for the third quarter ended September 30, 2009. Financial highlights from continuing operations for the third quarter of 2009 compared to ... in millions, except per share amounts), ... ... ...
... supply and demand starting to close, U.S. officials say, ... reported Wednesday the addition of another million doses H1N1 ... 23.2 million doses. , "We know people are ... now," Janet Napolitano, secretary of the U.S. Department of ...
... Application provides ... ... Harvard Health Publications Division of Harvard Medical School has launched an iPhone application focused ... knowledge of the experts at Harvard Medical School along with its long-standing expertise in publishing ...
Cached Medicine News:Health News:Warady & Davis LLP Named One of 'Top 50 Employers for Generation Y Chicago' 2Health News:Warady & Davis LLP Named One of 'Top 50 Employers for Generation Y Chicago' 3Health News:Board of Directors Declares Cash Distributions 2Health News:The Top 10 Business Mistakes Made By Physician Practices 2Health News:Carriage Services Announces Third Quarter 2009 Results 2Health News:Carriage Services Announces Third Quarter 2009 Results 3Health News:Carriage Services Announces Third Quarter 2009 Results 4Health News:Carriage Services Announces Third Quarter 2009 Results 5Health News:Carriage Services Announces Third Quarter 2009 Results 6Health News:Carriage Services Announces Third Quarter 2009 Results 7Health News:Carriage Services Announces Third Quarter 2009 Results 8Health News:Carriage Services Announces Third Quarter 2009 Results 9Health News:Carriage Services Announces Third Quarter 2009 Results 10Health News:Carriage Services Announces Third Quarter 2009 Results 11Health News:Carriage Services Announces Third Quarter 2009 Results 12Health News:Carriage Services Announces Third Quarter 2009 Results 13Health News:Carriage Services Announces Third Quarter 2009 Results 14Health News:Carriage Services Announces Third Quarter 2009 Results 15Health News:Carriage Services Announces Third Quarter 2009 Results 16Health News:Carriage Services Announces Third Quarter 2009 Results 17Health News:Carriage Services Announces Third Quarter 2009 Results 18Health News:Carriage Services Announces Third Quarter 2009 Results 19Health News:Carriage Services Announces Third Quarter 2009 Results 20Health News:1 Million More Doses of Swine Flu Vaccine on Hand 2Health News:Harvard Health Publications Launches H1N1 Flu iPhone Application 2Health News:Harvard Health Publications Launches H1N1 Flu iPhone Application 3
(Date:7/31/2014)... 2014  Zacks.com announces the list of stocks featured in ... discuss the latest news and events impacting stocks and the ... (Nasdaq: BIIB - Free Report ), Gilead (Nasdaq: ... - Free Report ), AbbVie (NYSE: ABBV - Free ... ). Today, Zacks is promoting its ,Buy, stock ...
(Date:7/31/2014)... July 31, 2014 Vermillion, Inc. (NASDAQ: VRML), a ... will hold a conference call on Thursday, August 14, 2014, ... second quarter ended June 30, 2014. Financial results will be ... Vermillion,s Chairman, President and CEO James LaFrance ... period. Date: Thursday, August 14, 2014 Time: 4:30 ...
(Date:7/31/2014)... , July 31, 2014 TB Alliance, ... developing better, faster and affordable treatments, announced the ... Vice President, External Affairs. Mr. Brock comes to ... of Major Donor Relations for WWF International (formerly ... role, Mr. Brock will guide the TB Alliance,s ...
Breaking Medicine Technology:The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 2The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 3The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 4The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 5The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 6Vermillion Sets Second Quarter 2014 Conference Call for Thursday, August 14, 2014 2TB Alliance Appoints Willo Brock Senior Vice President, External Affairs 2
... 1 The Michael J. Fox Foundation for ... to $6.5 million in total funding available under ... solutions to some of the most difficult hurdles ... PD.The Critical Challenges funding opportunities focus research efforts ...
... 31 Successful and seamless completion of clinical trial ... market research, an effective recruitment strategy, and project management ... Liz Moench notes: "This is achievable when clinical trial ... adds, "We had great team chemistry with the study ...
Cached Medicine Technology:Michael J. Fox Foundation Commits up to $6.5 Million in Funding for Critical Challenges in Parkinson's Disease 2Michael J. Fox Foundation Commits up to $6.5 Million in Funding for Critical Challenges in Parkinson's Disease 3Major Restless Legs Study Completes Enrollment With Support From MediciGlobal 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: