Navigation Links
Vaccine Shields Monkeys From Simian Form of HIV
Date:5/17/2009

Scientists inject antibody-coding genes directly into muscles

SUNDAY, May 17 -- Raising hopes for the development of an AIDS vaccine that might actually work, researchers report they were able to protect monkeys against infection with simian immunodeficiency virus (SIV), the primate version of HIV.

They did so by using a novel approach that delivered antibody-producing genes directly to the animals' muscles. Typically, vaccines are aimed at ramping up the immune system to fight off infection, but this strategy eliminated that middle step.

"Traditional approaches toward developing an HIV vaccine that have worked for other viruses like influenza have just has not worked for HIV and, quite frankly, might not work for a long time or ever," explained the study's author, Dr. Philip R. Johnson, chief scientific officer at Children's Hospital of Philadelphia and a professor of pediatrics at the University of Pennsylvania School of Medicine.

"But Mother Nature has allowed us a few breaks, in that we know that in a very few cases, people who have been infected for a very long time have been able to naturally develop antibodies that neutralize a lot of the circulating virus," he said. "So, we thought perhaps we could take the genes that represent these antibodies 'off the shelf,' so to speak, give them directly to patients and, in essence, bypass the immune system."

"So, first we worked through mice and showed we could do it with mice," Johnson explained. "And now we've shown that we can actually transfer these genes into monkeys and protect these animals from SIV."

The findings are in the May 17 online issue of Nature Medicine.

The researchers' efforts focused on preventing SIV infection in nine macaque monkeys who were "immunized" against SIV by inserting genes already known to express anti-SIV antibodies directly into the monkeys' muscles.

Once the genes were injected, they pr
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. DNA vaccine against multiple sclerosis appears safe, potentially beneficial
2. HPV vaccine does not appear to be effective for treating pre-existing HPV infection
3. Vaccine Stops Alzheimers Brain Tangles
4. Human Papilloma Virus vaccines may decrease chances of oral cancer
5. U.S. Teens Fall Short on Vaccine Coverage
6. Nasal Anthrax Vaccine Proves Effective in Animal Study
7. Hot ice, measuring depression, perfect invisibility and flu vaccine incentives
8. Bioniche Receives $2 Million Government Grant For Market Development Related to its E. coli O157:H7 Cattle Vaccine
9. Iomai Patch-Based Vaccine Cut Rate of Travelers Diarrhea by 75 Percent in Phase 2 Field Study
10. FDA approves expanded label for FluMist (influenza virus vaccine live, intranasal) to include childr
11. MedImmune Licenses Reverse Genetics Technology to GlaxoSmithKline for Use in Influenza Vaccine Development and Production
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vaccine Shields Monkeys From Simian Form of HIV
(Date:8/21/2014)... NC -- Researchers have pinpointed the environmental source of ... Southern California for decades. It literally grows on trees. ... of a 13-year-old girl, who spent the summer gathering ... hardest hit by infections of the fungus named ... Cryptococcus , which encompasses a number of species including ...
(Date:8/21/2014)... 21, 2014 (HealthDay News) -- Being born at a low ... 2 diabetes, a new study suggests. The findings may ... that has a high prevalence of low birth weight, the ... women found that those with a low birth weight were ... those with a normal birth weight. The risk of diabetes ...
(Date:8/21/2014)... A new study published this week in the ... with speech problems from 2001-02 to 2010-11 among U.S. ... disability associated with hearing problems. The data underscore the ... who are experiencing communication disorders, according to the ... broader level, the new study, Changing Trends of ...
(Date:8/21/2014)... Hollywood, FL (PRWEB) August 21, 2014 ... being published today in The Journal of the American ... significantly more invasive cancers and reduces unnecessary recalls. Memorial ... participate in the study. , “This study confirms what ... the invasive, harmful cancers we want to find and, ...
(Date:8/21/2014)... According to a new market report published ... - Home Theatre in-a-box, Home audio systems, Home radios, ... Size, Share, Growth, Trends and Forecast, 2013 - 2019,” ... 2012 and is expected to reach USD 20.68 billion ... 2013 to 2019. Europe was the largest contributor to ...
Breaking Medicine News(10 mins):Health News:Fungus deadly to AIDS patients found to grow on trees 2Health News:Low Birth Weights May Put Black Women at Risk for Diabetes 2Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 2Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 3Health News:Dr. Mary Hayes: Study Shows 3D Mammography Finds More Invasive Cancers While Reducing Unnecessary Recalls 2Health News:Home Audio Equipment Market Expected to Reach USD 20.68 Billion in 2019 2Health News:Home Audio Equipment Market Expected to Reach USD 20.68 Billion in 2019 3
... therapy to significantly improve overall survival in patients with ... 20 Bayer HealthCare Pharmaceuticals and Onyx ... that the Ministry of Health, Labour and Welfare (MHLW) ... treatment of patients with unresectable hepatocellular carcinoma (HCC), a ...
... Recondo Technology, a leading provider of revenue cycle ... Harry Gambill and Jeff Fritz have joined the ... Gambill began with TransUnion in 1985 and served ... During his 16-year tenure, TransUnion grew from a ...
... high schoolers take to the stage at the House of Blues ... creative seat belt messagesCLEVELAND, May 20 Local teens had a ... at the House of Blues at noon on Tuesday, May 19, ... It High School Seat Belt Challenge, sponsored by Kohl,s, wrapped ...
... C. Mendell and Lloyd H. Malchow Join Digirad Board ... DRAD ) today announced that it has ... H. Malchow to its Board of Directors, effective immediately. ... board to a total of seven members."Steve and Lloyd ...
... 403(b) market are pushing nonprofit clients to eliminate options for participants by ... with 403(b)connect, now is the time to keep provider and investment choices ... ... 2009 -- The new fully automated 403(b)connect by se2 is ...
... CoSign® digital signatures fully integrate with Adobe LiveCycle® ES, decreasing costs ... , ... San Francisco, CA (PRWEB) May 20, 2009 -- ... the CoSign digital signature (standard electronic signature) solution , and ...
Cached Medicine News:Health News:Nexavar Approved in Japan for the Treatment of Advanced Liver Cancer 2Health News:Nexavar Approved in Japan for the Treatment of Advanced Liver Cancer 3Health News:Nexavar Approved in Japan for the Treatment of Advanced Liver Cancer 4Health News:Nexavar Approved in Japan for the Treatment of Advanced Liver Cancer 5Health News:Nexavar Approved in Japan for the Treatment of Advanced Liver Cancer 6Health News:Recondo Technology Announces Two New Board Members 2Health News:Rainbow Babies & Children's Hospital's Use It or Lose It High School Seat Belt Challenge Brings Out the Creativity in Cuyahoga County Teens 2Health News:Rainbow Babies & Children's Hospital's Use It or Lose It High School Seat Belt Challenge Brings Out the Creativity in Cuyahoga County Teens 3Health News:Digirad Names Two Veteran Healthcare Executives to Board 2Health News:Digirad Names Two Veteran Healthcare Executives to Board 3Health News:Digirad Names Two Veteran Healthcare Executives to Board 4Health News:403(b) Administration Now Turn-Key with New 'Single Solution/Multi-Provider' Web Hosted Platform - 403(b)connect 2Health News:403(b) Administration Now Turn-Key with New 'Single Solution/Multi-Provider' Web Hosted Platform - 403(b)connect 3Health News:SAFE-BioPharma Webinar Featuring ARX's Digital Signature Solution and Adobe LiveCycle Combined Solution 2Health News:SAFE-BioPharma Webinar Featuring ARX's Digital Signature Solution and Adobe LiveCycle Combined Solution 3
(Date:8/21/2014)... ARMONK , N.Y. and HAMBURG, Germany ... today announced it is collaborating with Deutsches Elektronen-Synchrotron ( ... Germany , to speed up management and ... Big Data and Analytics architecture based on ... gigabyte per second of data at peak performance and ...
(Date:8/21/2014)... 2014  ACI Clinical ( www.aciclinical.com ) announces ... Committees. Using this solution, trial sponsors ... standard costs and receive the same expertise that ... services. Leveraging a decade of DMC ... development, statistical programming and meeting facilitation), ACI analyzed ...
(Date:8/21/2014)... 21, 2014 CVS Caremark Corporation (NYSE: ... Yields and consideration payable in connection with its previously announced ... 2014 for (1) any and all of its 6.250% Senior ... up to a maximum amount of its 6.125% Senior Notes ... Notes due 2017 (collectively, the "Maximum Tender Offer Notes" and ...
Breaking Medicine Technology:DESY and IBM Develop Big Data Architecture for Science 2DESY and IBM Develop Big Data Architecture for Science 3ACI Clinical: Innovation and Savings in Data Safety Monitoring Committees 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 3CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 4CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 5CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 6
This free-standing work station safely ventilates fumes upwards, away from the work surface. Optional Exhaust Purification System features bonded charcoal filters that remove organic chemical vapors ...
... is the same as model ... flat internal baffle across the ... baffle slopes forward, leaving space ... sweep the deck and space ...
... The Benchtop Fume Hood is an ... installations in which a number of fume ... schools, junior colleges and universities. Features include ... polyethylene with rounded inside corners for easy ...
This is the second generation of the famous A/O sliding microtome, manufactured in the United States under the Leica trademark....
Medicine Products: