Navigation Links
Vaccine Could Cut Bouts With Stomach Flu
Date:2/12/2008

Controlling quickly mutating noroviruses might mean yearly changes in formula

TUESDAY, Feb. 12 (HealthDay News) -- It may be possible to develop a vaccine to control noroviruses -- a common cause of stomach flu -- but it's likely a such a vaccine would have to be changed every year because the viruses evolve quickly to avoid attacks by the immune system, new research suggests.

Noroviruses infect cells after attaching to histo-blood group antigens (HBGA), molecules located on the surface of cells. HBGAs are a family of complex sugar molecules that exist in great variety among humans, according to background information in the study in the journal PLoS Medicine.

Ralph Baric, of the University of North Carolina at Chapel Hill, and his colleagues found this large variety of HBGAs contributes to recurrence of norovirus outbreaks, even among people who have previously been exposed to the virus and have developed antibodies against it.

The researchers analyzed noroviruses that caused several outbreaks and found that the viruses evolved to avoid attack by immune system antibodies.

Over time, some of the norovirus strains developed a shape that enabled them to bind other forms of HBGA. These viruses were then resistant to previously existing antibodies and able to infect cells carrying that particular form of HBGA. These viruses could then cause a new outbreak, with the cycle repeating itself, the researchers said.

Noroviruses, which can cause nausea, vomiting and diarrhea, are highly contagious. Most people recover within a few days, but the viruses can cause severe problems in very young and in old people. There is no specific treatment for norovirus infection.

More information

The U.S. Centers for Disease Control and Prevention has more about noroviruses.



-- Robert Preidt



SOURCE: PLoS Medicine, news release, Feb. 11, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Iomai Study Shows Self-Applied Travelers Diarrhea Vaccine Patch Comparable to Clinician-Applied Vaccine Patch
2. Meningitis vaccine study gets £200,000 boost
3. Tattooing Best Way to Deliver DNA Vaccines
4. Novel molecules developed at UB can boost vaccine potency
5. USDA Agrees to Grant Conditional License to Bioniche for its E. coli O157:H7 Cattle Vaccine
6. Another Study Finds No Link Between MMR Vaccine and Autism
7. New hospital standards needed for pediatric flu vaccines
8. Experimental Vaccine Halts Prostate Cancer in Mice
9. Novel vaccine concept developed by scientists at the Wistar Institute
10. Mercury in Childhood Vaccines Excreted Quickly
11. Childhood Vaccines Save Lives, March Of Dimes Says
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vaccine Could Cut Bouts With Stomach Flu
(Date:2/5/2016)... ... ... After years as an active staff surgeon and having served as the director ... transitioned to chief of the Division of Plastic Surgery at what is now known ... began a second three-year term in January of 2016. , The original selection was ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Regular gym users ... themselves having to wait longer to access the treadmills. It’s a predictable trend. After ... to lose weight and get in shape by joining gyms, starting new walking or ...
(Date:2/5/2016)... ... February 05, 2016 , ... Dr. Justin Scott and Dr. ... Annual No Cost Dental Day to individuals in need. The event is scheduled to ... No Cost Dental Day is to provide dental care to community members in need. ...
(Date:2/5/2016)... ... 05, 2016 , ... Health and wellness is a topic that should concern ... they are experiencing an illness. Migraines are a severe form of a headache and ... would not wish the pain on their worst enemy, the feeling can last for ...
(Date:2/5/2016)... ... 05, 2016 , ... –This week, Atascadero water heater company First Call ... heater. To view the report, click here or see below. , ... their pros and cons, the type chosen is almost entirely up to personal preference. ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... , Feb. 4, 2016 Frontier Pharma: ... Commercializing First-in-Class Innovation Chronic Obstructive ... with chronic inflammation of the airways and lungs. ... symptoms make the disease one of the leading ... death in the world. COPD is linked to ...
(Date:2/4/2016)... COLUMBUS, Ohio, Feb. 4, 2016 Mettler-Toledo International ... results for 2015.  Provided below are the highlights: ... the quarter compared with the prior year.  Reported sales ... in the quarter. , Net earnings per diluted ... in the prior- year period.  Adjusted EPS was $4.65, ...
(Date:2/4/2016)... 4, 2016 In response to the opioid abuse ... Commissioner for Medical Products and Tobacco, along with other FDA ... agency,s approach to opioid medications. The plan will focus on ... in pain access to effective relief. ... , Re-examine the risk-benefit paradigm for opioids and ensure that ...
Breaking Medicine Technology: