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VYVANSE provided behavior, inattention and math test score improvements in children with ADHD
Date:10/29/2008

bility, upper abdominal pain, and affect lability.

VYVANSE, which was introduced in July 2007 for the treatment of ADHD in children aged 6 to 12 years, was approved in April 2008 to treat ADHD in adults. VYVANSE is now available in six dosage strengths of 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, and 70 mg. To date, more than 3 million VYVANSE prescriptions have been filled.

VYVANSE is a therapeutically inactive prodrug, in which d-amphetamine is covalently bonded to l-lysine, and after oral ingestion it is converted to pharmacologically active d-amphetamine. The conversion of VYVANSE to d-amphetamine is not affected by gastrointestinal pH and is unlikely to be affected by alterations in GI transit times.


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