Navigation Links
VCU receives grant to study molecular marks left by childhood adverse experiences
Date:7/22/2014

Virginia Commonwealth University has received a five-year, $3 million grant to study how adverse experiences such as severe illnesses, neglect and maltreatment during childhood leave molecular marks in DNA that predict health risks later in life.

The Center for Biomarker Research and Personalized Medicine at the VCU School of Pharmacy, in collaboration with Duke University School of Medicine, will conduct the five-year study, which is funded by the National Institutes of Health, National Institute of Mental Health.

"Childhood adverse experiences such as severe illness, neglect or maltreatment have been robustly linked to psychiatric and other medical conditions where the consequences often persist far into adulthood," said Edwin van den Oord, Ph.D., director of the Center for Biomarker Research and Personalized Medicine and principal investigator on the study. "Our goal is to study how these early adverse experiences become biologically embedded and how they create long-term health risks."

"An accumulation of evidence from animal and human research implicates DNA methylation," said Karolina Aberg, Ph.D., associate director of the Center for Biomarker Research and Personalized Medicine. "Methylation is a process that involves small chemical changes to the DNA that can be the result of the environmental factors such as adverse events."

Aberg is responsible for the laboratory components of the project that involve measuring the methylation status of approximately 28 million possible sites in the human genome using the most recent high throughput sequencing technology.

The project capitalizes on a study started at Duke University about 20 years ago that involved 9- to 13-year-old children. That study continues today as the participants are in their 30s. Because detailed assessments and blood samples were obtained at two-year intervals, the investigators can compare DNA methylation profiles before and after adverse events
'/>"/>

Contact: Eric Peters
petersem@vcu.edu
804-828-0563
Virginia Commonwealth University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Loyola Cancer Center receives Outstanding Achievement Award
2. MU receives national award for using mind-body approach to improve health
3. Neuropsychologist receives University of Houstons highest faculty honor
4. Boston researcher, surgical oncologist receives national award
5. LA BioMed receives Grand Challenges Explorations grant
6. Lawson researcher receives 1 of first-ever Pfizer Psychiatry Research Awards
7. Dr. Arthur Slutsky, vice-president of research at St. Michaels, receives lifetime award
8. UC San Diego Superfund Research Program receives $15 million grant renewal
9. Markey receives $6.25 million to study deadly blood and bone marrow disease
10. Feola, at University of Kentucky, receives NIH grant to study cystic fibrosis
11. UC Santa Barbaras Kavli Institute receives 2 grants to explore interface of physics and biology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... NV (PRWEB) September 30, 2014 Fat ... nutrition specialist and best-selling author Mike Geary that is helping ... transform their body into a fat-burning machine in less than ... an investigative review. , “In our culture that is ... be hard to decipher what is really fact and fiction ...
(Date:9/30/2014)... VisitandCare.com reports that revenue ... up more than 79 percent in 2014, marking five ... reported total revenue tripled for its entirety of partnered ... strategy has allowed them to partner with plastic ... comfort and privacy — with state-of-the-art surgical atmospheres aimed ...
(Date:9/30/2014)... Ohio (PRWEB) September 30, 2014 ... new viral strains emerging every day, it’s a ... system. The EnviroShield system is an electro-static ... allows applications to surface normally missed with spray-on ... spray nozzle that adds an electrostatic negative charge ...
(Date:9/30/2014)... Dr. Karl R.O.S. Johnson, DC, has developed ... care that is dramatically improving the health and lives ... & Nutrition—applies a proprietary, multi-dimensional approach that goes beyond ... of inflammation, neurology of the joint and neurology of ... brain to the spine, to the legs, knees and ...
(Date:9/30/2014)... should cover low-dose computed tomography lung cancer screening for ... of more than 60 patient and medical groups says. ... the Society of Thoracic Surgeons, the American College of ... of Clinical Oncology, made its point in a letter ... Medicaid Services (CMS). Such screening reduces lung cancer ...
Breaking Medicine News(10 mins):Health News:Fat Burning Kitchen: Review Exposes Mike Geary’s 24-Hour Diet Transformation for Helping the Body Burn Fat Through a Natural Diet 2Health News:Fat Burning Kitchen: Review Exposes Mike Geary’s 24-Hour Diet Transformation for Helping the Body Burn Fat Through a Natural Diet 3Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 2Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 3Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 4Health News:Columbus Janitorial Company Announces New Disinfecting System for your workplace 2Health News:Newly Developed Program Eases Chronic Knee Pain without Surgery and in as Little as Two Days 2Health News:Newly Developed Program Eases Chronic Knee Pain without Surgery and in as Little as Two Days 3Health News:Groups Call for Medicare Coverage of Lung Cancer Screening 2
... with ... summer ailments, NORTH BERGEN, N.J., July 1 ... first aid kit in their suitcase. The,big question is what should they ... Shoppe,s Homeopathic Expert, Carrie,Plumley, has some suggestions for travelers this summer., ...
... identify with determine how they decide to control their own ... Eleanor Mackey from the Children,s National Medical Center in Washington ... University of Miami. Also influencing weight control behavior is girls, ... what others consider normal body weight. These results have just ...
... Base and Increase International,Liquidity, SYDNEY, Australia ... (ASX: QRX), a clinical-stage specialty pharmaceutical,company focused ... for,pain and central nervous system (CNS) disorders, ... Depositary Receipt (ADR) program has,been listed on ...
... WASHINGTON, July 1 Beginning July 6, Sharing,Miracles -- ... and inspirational stories of real patients -- will feature,four-time ... the,program will debut in Los Angeles on KCOP-TV at ... across the United States., Diver Greg Louganis won ...
... Accenx Technologies,Inc., is the premier sponsor of ... to Interoperability. The two-day event, held in Boston, ... Information Exchange (HIE) to the,next level., Accenx ... offering a Software as a Service (SaaS) solution ...
... and administration in Penn State,s College of Health and ... grant from the Robert Wood Johnson Foundation (RWJF) to ... Forces for Quality (AF4Q).", This grant is in addition ... Johnson Foundation in 2007 and expands the scope of ...
Cached Medicine News:Health News:Homeopathic First Aid Kit: Solutions for Summer's Little Bummers 2Health News:Homeopathic First Aid Kit: Solutions for Summer's Little Bummers 3Health News:Does this make me look fat? 2Health News:QRxPharma Begins Trading on the International OTCQX 2Health News:QRxPharma Begins Trading on the International OTCQX 3Health News:QRxPharma Begins Trading on the International OTCQX 4Health News:'Sharing Miracles' Television Program to Feature Olympic Gold Medal-Winner Greg Louganis 2Health News:'Sharing Miracles' Television Program to Feature Olympic Gold Medal-Winner Greg Louganis 3Health News:'Sharing Miracles' Television Program to Feature Olympic Gold Medal-Winner Greg Louganis 4Health News:'Sharing Miracles' Television Program to Feature Olympic Gold Medal-Winner Greg Louganis 5Health News:'Sharing Miracles' Television Program to Feature Olympic Gold Medal-Winner Greg Louganis 6Health News:Accenx Technologies, a Premier Sponsor as the Educational Underwriters of the 3rd Annual World Congress Leadership Summit on The Road to Interoperability 2Health News:Researcher receives $4 million from RWJ Foundation to study health quality reform project 2
(Date:9/30/2014)... -- Decision Resources Group finds that the markets for peripheral ... Russia , India ... see robust expansion as these economies expand and as ... revenues will be somewhat impeded by poor distribution of ... and demand for low-cost products, the market will ultimately ...
(Date:9/30/2014)... , Sept. 30, 2014  Decision Resources Group finds that the ... Australia , China , India ... at a strong rate through 2023. Dental implant procedure volumes will ... patient awareness rises. Other key findings from Decision Resources ... implant market: , Dental implant penetration: Penetration of ...
(Date:9/30/2014)... Sept. 30, 2014  According to their CEO, ... cancer clinical trials is going through a complete ... the work of the current clinical trial management ... ,next generation, clinical trials, which will ultimately drive ... The company has been recognized by the ...
Breaking Medicine Technology:Brazilian, Russian, Indian and Chinese Markets for Peripheral Vascular Devices Will See Strong Expansion Through 2023 2Brazilian, Russian, Indian and Chinese Markets for Peripheral Vascular Devices Will See Strong Expansion Through 2023 3Asia Pacific Dental Implant Market Will Grow at a Strong Rate Through 2023 2Asia Pacific Dental Implant Market Will Grow at a Strong Rate Through 2023 3Small Denver Company Pharmatech driving a large revolution in how cancer clinical trials are managed 2
... 2012  Based on its recent analysis of the ... recognizes Sensear with the 2012 North American Frost ... its "high-noise communication" devices, including earplugs and earmuffs ... still enabling the user to remain fully aware ...
... Carla Corkern, Chief Executive Officer at Talyst , was ... recognizes entrepreneurs whose ingenuity, hard work and perseverance have created ... originated in 1986 and has grown to 26 programs in ... the world. "Talyst is a leader in ...
Cached Medicine Technology:Frost & Sullivan Recognizes Sensear for Innovative and Effective Product Differentiation in the PPE Market 2Frost & Sullivan Recognizes Sensear for Innovative and Effective Product Differentiation in the PPE Market 3Frost & Sullivan Recognizes Sensear for Innovative and Effective Product Differentiation in the PPE Market 4
... Trappers are ideal for use with custom ... Finger Trappers' non-slip foam lining replaces fingernail ... in traction. These are truly the "No ... packages of 5 and boxes of 25. ...
One splint does it all....
... heavy duty, controlled stretch knee brace provides ... or for those individuals with a history ... metal bars provide excellent side-to-side support, yet ... The elastic sleeve supports the entire knee ...
... is a heavy duty, controlled stretch knee ... pain while allowing full range of motion. ... bend with the knee, and help to ... wearing comfort. This is an excellent ...
Medicine Products: