Navigation Links
VCU findings may help explain some major clinical symptoms of preeclampsia
Date:1/4/2011

ood vessel contraction by activation of a receptor known as PAR1, which according to Walsh, could explain the hypertension, or high blood pressure, of women with preeclampsia.

"This finding may be especially important for preeclampsia because we found increased amounts of PAR1 in blood vessels of preeclamptic women as compared to normal pregnant women. MMP-1 activation of PAR1 is a totally new mechanism to explain hypertension," Walsh said.

PAR1 is best known for its role in the coagulation of blood, but it is not known for a role in hypertension, said Walsh.

Further, the team showed that neutrophils, or white blood cells, and neutrophil products increase MMP-1 and PAR1. According to Walsh, neutrophil infiltration may be the cause of the increase in MMP-1 and PAR1 in blood vessels that leads to vessel dysfunction and clinical symptoms of preeclampsia.

"Activation of the PAR1 receptor by MMP-1 causes changes in the endothelial cells of blood vessels that we speculated could result in contraction of blood vessels. This new information provides a rationale for the use of PAR1 inhibitors to treat preeclampsia," said Walsh.


'/>"/>

Contact: Sathya Achia Abraham
sbachia@vcu.edu
804-827-0890
Virginia Commonwealth University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Addiction research: Key findings every month
2. Encouraging findings suggest new avenues for treating liver disease in overweight Americans
3. Latest Findings Back Mammograms for Women in Their 40s
4. National committee releases findings on transforming and improving the nursing profession
5. Study findings show value of dietary supplement SAMe in treatment of adults with major depressive disorders
6. New findings further clarify breast cancer risk with hormone therapy
7. Mayo Clinic researchers share latest findings in CT radiation dose reduction efforts
8. U. Iowa biologists publish findings on cell interactions
9. Strong scientific findings presented at AIDS 2010 point to promise ahead and underscore the need to stay the course
10. Tel Aviv University Fertility Research Confirms New York Center's DHEA Findings
11. Fresh findings about chickenpox could lead to better blood tests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... that elderly men should not be routinely screened for ... a new study led by researchers at Henry Ford ... in JAMA Internal Medicine , focused on the ... for prostate cancer., "We found that the effect of ... men in particular has been minimal at best," says ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 ChopChop ... Bill Yosses and Yonah Kalikow, 10-year-old Massachusetts’s winner of the ... twist on hummus, the classic Middle Eastern bean dip. Watch ... stage how kids can create their own healthy dips at ... at the third annual Let’s Talk About Food Festival ...
(Date:9/18/2014)... Technology Association of Georgia in collaboration with TAG ... Savvy Awards this week at a special ceremony held ... Downtown Atlanta. The event celebrates Georgia’s best and brightest ... with the 2014 TAG Social Savvy People’s Choice Award ... 6 other award categories: , ,     UPS ...
(Date:9/18/2014)... 18, 2014 Once again, Hickman’s Family ... restaurants around the Valley to celebrate PJs & Eggs. ... Egg Day”: Friday, October 10, 2014. The “breakfast for ... to benefit Arizona’s Children Association (AzCA) foster care programs ... at each participating restaurant on October 10 are invited ...
(Date:9/18/2014)... cancer-hampering molecules show promise in slowing the progression ... often linked to asbestos. Scientists from Case Western ... demonstrate that application of curcumin, a derivative of ... of a protein inhibitor known to combat the ... the Aug. 14 online edition Clinical Cancer ...
Breaking Medicine News(10 mins):Health News:Professional recommendations against routine prostate cancer screening have little effect 2Health News:Award-Winning Cooking Magazine for Kids Challenges Former White House Pastry Chef and 10-Year-Old Chef to Cook Up a Healthy Snack 2Health News:Award-Winning Cooking Magazine for Kids Challenges Former White House Pastry Chef and 10-Year-Old Chef to Cook Up a Healthy Snack 3Health News:Winners Honored at 2014 TAG Social Savvy Awards 2Health News:Winners Honored at 2014 TAG Social Savvy Awards 3Health News:October 10th Is 6th Annual PJs & Eggs: Hickman’s Family Farms and Breakfast Restaurants Partner to Benefit Arizona Foster Children 2Health News:Curcumin, special peptides boost cancer-blocking PIAS3 to neutralize STAT3 in mesothelioma 2Health News:Curcumin, special peptides boost cancer-blocking PIAS3 to neutralize STAT3 in mesothelioma 3
... The most common form of thalassaemia disease may ... ,Hemoglobin E ? thalassaemia—the commonest form of ... without transfusion in many patients, suggests a research ... The Lancet. The authors state that the finding ...
... of researchers at Vienna University have said they are ... it will be effective against lung cancer//. , ... much more research was still needed before the new ... statement Tuesday. , ,"In fact it's a paradox," ...
... to complex problems lies at hand but that is the ... new anti obesity drug//. A weight control protein with a ... content may yield new approaches for treating obesity and type ... particular variants of the protein SH2-B might underlie obesity in ...
... found a new protein which may be responsible for the ... is known as MSF protein is produced in high quantity ... produced may be responsible for the severity of disease progression. ... protein, the scientists are looking into the properties of these ...
... vulnerable to suffer from the dreaded disease of multiple ... risk//. ,According to the most complete genetic study ... from Vanderbilt University in Nashville, Tennessee at the 130th ... Diego, a cluster of genes on chromosome six is ...
... research report published in the latest issue of Archives ... ready to deal with the threat of bio-terrorism that ... ,More than one-half of 631 physicians tested were ... likely to be used by bio-terrorists. However, test scores ...
Cached Medicine News:Health News:Flu Vaccine Can Be Used To Treat Lung Cancer 2Health News:An Answer To Obesity: Weight Control Protein 2
(Date:9/18/2014)... Sept. 18, 2014   Regulus Therapeutics Inc ... company leading the discovery and development of innovative ... its ATHENA natural history of disease study in ... disease with no approved therapy. The ATHENA study ... renal function markers such as Glomerular Filtration Rate ...
(Date:9/18/2014)... and ROCKVILLE, Md. , ... SPPI ), a biotechnology company with fully integrated ... in hematology and oncology, and CASI Pharmaceuticals, Inc. (Nasdaq: ... the acquisition, development and commercialization of innovative therapeutics addressing ... market with a primary focus on China ...
(Date:9/18/2014)... Sept. 18, 2014  RXi Pharmaceuticals Corporation ... company focused on discovering, developing and commercializing ... using RNA-targeted technologies, today announced that the Company,s ... Geert Cauwenbergh , will present at the ... on Wednesday, September 24, 2014 at 11:20 ...
Breaking Medicine Technology:Regulus Initiates ATHENA Natural History of Disease Study in Alport Syndrome Patients 2Regulus Initiates ATHENA Natural History of Disease Study in Alport Syndrome Patients 3Regulus Initiates ATHENA Natural History of Disease Study in Alport Syndrome Patients 4Regulus Initiates ATHENA Natural History of Disease Study in Alport Syndrome Patients 5Regulus Initiates ATHENA Natural History of Disease Study in Alport Syndrome Patients 6Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 2Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 3Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 4Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 5Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 6Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 7Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 8Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 9Spectrum Pharmaceuticals Out-Licenses Rights for Greater China to CASI Pharmaceuticals for Three of Its Drugs 10RXi Pharmaceuticals to Present at the 7th Annual BioPharm America Conference 2RXi Pharmaceuticals to Present at the 7th Annual BioPharm America Conference 3
... 2011 On Sunday, August 21, veterinary cardiologists are ... the Mobile Dog Heart Health Tour will stop with ... examinations at Peters Park Dog Run. (Photo: ... free heart health screenings, veterinarians will be available to ...
... Unilife Corporation ("Unilife" or the "Company") (NASDAQ: ... it has finalized a previously disclosed Equipment Financing ... $10 million in available funding. This agreement will ... finance the automated assembly line now manufacturing the ...
Cached Medicine Technology:Free Dog Heart Health Screenings Available August 21 in Boston 2Unilife Signs $10 Million Equipment Financing Agreement 2Unilife Signs $10 Million Equipment Financing Agreement 3Unilife Signs $10 Million Equipment Financing Agreement 4
Caspar Curette, 250 mm, 10"....
Bone Curette, 160 mm...
Bone Curette, 145 mm...
Bone Currettes...
Medicine Products: