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VCU Massey research finds new link between inflammation and cancer
Date:8/16/2010

kappaB.

These findings also provide an explanation for the numerous observations of the importance of the enzyme that produces S1P, SphK1, in protection of cancer cells against chemotherapeutic drugs and the correlation of its levels with poor prognosis of many types of cancers, including breast, colorectal and brain.

Spiegel hopes that specific SphK1 inhibitors they are developing will pave the way for future potent and specific drugs that target SphK1 for the treatment of cancer.


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Contact: Jenny Owen
jrowen2@vcu.edu
804-628-2111
Virginia Commonwealth University
Source:Eurekalert  

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