Navigation Links
VCU Massey Cancer Center spearheads novel clinical study for lymphoma patients
Date:9/2/2008

The Virginia Commonwealth University Massey Cancer Center recently opened a National Cancer Institute (NCI)-sponsored, phase II clinical study for certain sub-types of non-Hodgkin's lymphoma.

The study is based on research from VCU Massey Cancer Center as well as other centers suggesting that combining two novel, recently approved drugs that have shown effectiveness in certain blood cancers may be active in patients with diffuse large B-cell lymphoma, or mantle cell lymphoma. The study is intended for patients whose disease has progressed following treatment with other regimens.

Other NCI centers participating in this novel lymphoma study through the NCI's Southeast Phase II Consortium include H. Lee Moffitt Cancer Center and Research Institute (Tampa, Fla.), which is the coordinating center; the University of North Carolina Lineberger Comprehensive Cancer Center (Chapel Hill, N.C.); and the Vanderbilt-Ingram Cancer Center (Nashville, Tenn.). Also planning to participate are Montefiore-Einstein Cancer Center (New York); and New York Presbyterian Hospital / Weill Cornell Medical College, both of which are in the NCI-sponsored New York Phase II Consortium.

The investigators hope to learn whether these types of lymphoma respond to treatment with the combination of bortezomib, marketed as Velcade, and vorinostat, marketed as Zolinza. They also intend to learn about the side effects of this drug regimen and whether certain features of these lymphomas might predict for response to this regimen.

Steven Grant, M.D., principal investigator of the study and associate director for translational research at VCU Massey Cancer Center, is among a number of researchers worldwide who have reported synergistic interactions between proteasome inhibitors such as bortezomib and histone deacetylase inhibitors such as vorinostat in leukemia and other hematologic malignancies. Other cancer centers are currently exploring this drug combination in
'/>"/>

Contact: Andrea Butler
albutler@vcu.edu
804-628-2111
Virginia Commonwealth University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. VCU Massey Cancer Center to partner with Israeli biotech firm
2. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
3. Survival differences by race most apparent in advanced stages of breast cancer
4. MRI finds breast cancer before it becomes dangerous
5. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
6. Pathway links inflammation, angiogenesis and breast cancer
7. Radiologists encouraged to look beyond cancer for clinically unseen diseases
8. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
9. Immune deficiency linked to a type of eye cancer
10. Drop in breast cancer incidence linked to hormone use, not mammograms
11. Breast cancer prevention practices vary across Canada
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2015)... ... ... On Tuesday, July 28th, Symantec released a security industry whitepaper on ... attack on Anthem Inc. which resulted in one of the largest data breaches in ... phishing campaigns. , For Joe Caruso, founder and CEO/CTO of Global ...
(Date:8/1/2015)... ... August 01, 2015 , ... BeverlyD, owner and founder of BeverlyD Luxe ... the very first small business donation to kick off the campaign for healing and ... Her legacy includes a complete line of raw, organic hair care products, as well ...
(Date:8/1/2015)... , ... August 01, 2015 , ... On March 19, 2015 Phil Valentine – the ... of the Appalachian Trail by stepping off Springer Mountain and heading north. Since ... July 26th Phil reached Connecticut and was greeted by friends and family. He visited ...
(Date:7/31/2015)... ... 31, 2015 , ... Ticket Down is a reputable source of authentic tickets for the ... Fans of every genre of music will have an act they are excited to ... the festival, the following artists will perform: Sam Smith, Coldplay, Kenny Chesney, The Who, ...
(Date:7/31/2015)... ... August 01, 2015 , ... The Honor Society of Nursing, Sigma ... the Future of Nursing (GAPFON) 20-21 July 2015 in San Juan, Puerto Rico. Key ... meeting. , Dr. Silvia Cassiani, Advisor, Nursing and Allied Health Personnel Development, Unit of ...
Breaking Medicine News(10 mins):Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 2Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 3Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 4Health News:March4thforWellBeing Foundation Kickoff 2Health News:Connecticut Executive Hikes Appalachian Trail to Raise Awareness About Recovery. 2Health News:Cheap 2015 iHeartRadio Music Festival Tickets in Las Vegas at MGM Grand Garden Arena: Ticket Down Slashes Ticket Prices on the iHeart Radio Music Festival in Vegas 2Health News:Cheap 2015 iHeartRadio Music Festival Tickets in Las Vegas at MGM Grand Garden Arena: Ticket Down Slashes Ticket Prices on the iHeart Radio Music Festival in Vegas 3Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 2Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 3Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 4
... , , LOVELAND, Colo., Dec. 14 ... or the "Company"), a leading provider of veterinary ... customer installation of the Company,s new DRI-CHEM® 7000 ... http://www.newscom.com/cgi-bin/prnh/20000622/HESKALOGO ) , Customers receiving these analyzers ...
... , , ... the grassroots cowboy campaign to fight breast cancer, celebrated its ... Night at the Wrangler National Finals Rodeo (Wrangler NFR) in ... rodeo cowboys, the support of the western industry and rodeo ...
... , ... CT procedures vary widely and are higher than generally thought, raising concerns about increased risk ... (UCSF) imaging specialists. , ... San Francisco, CA (Vocus) December 14, 2009 -- Radiation doses from common CT procedures vary ...
... The Hemophilia Federation of America (HFA) expresses its concern ... and the American Red Cross of Pennsylvania /New Jersey. The ... safe blood to laboratories. The blood is distilled into products ... von Willebrand disease. , The Division of Blood Services ...
... and shouldn,t worry most users, researcher says , MONDAY, ... antidepressants may have a small but statistically significant increased ... on the medications, a new study finds. , "But ... Dr. Jordan W. Smoller, an associate professor of psychiatry ...
... to better treatments for asthma, COPD, researchers say , ... five genetic variants that influence lung function, a finding ... diseases. , The international team of researchers compared lung ... million sites across the human genome in more than ...
Cached Medicine News:Health News:Heska Announces Installation of New Chemistry Analyzer 2Health News:Heska Announces Installation of New Chemistry Analyzer 3Health News:Tough Enough To Wear Pink(TM) Celebrates Fifth Anniversary 2Health News:Tough Enough To Wear Pink(TM) Celebrates Fifth Anniversary 3Health News:Tough Enough To Wear Pink(TM) Celebrates Fifth Anniversary 4Health News:Variable Doses of Radiation Raise Safety Concerns for CT Procedures 2Health News:Variable Doses of Radiation Raise Safety Concerns for CT Procedures 3Health News:Variable Doses of Radiation Raise Safety Concerns for CT Procedures 4Health News:Variable Doses of Radiation Raise Safety Concerns for CT Procedures 5Health News:HFA Voices Blood Safety Concerns 2Health News:Antidepressants May Raise Women's Stroke Risk 2Health News:Antidepressants May Raise Women's Stroke Risk 3
(Date:7/31/2015)... LAKE, N.J. and SAN DIEGO ... today that its parent company Eisai Co., Ltd. (Headquarters: ... Haruo Naito , "Eisai") and Halozyme Therapeutics, Inc. (Headquarters: ... CEO: Dr. Helen Torley , "NASDAQ: HALO") have ... mesylate (brand name: Halaven ® , "eribulin") in combination ...
(Date:7/31/2015)... 2015 Magnaquest, a leading ... and cloud computing operators has signed a Proof ... for Internet of Things (IoT) related initiative. The ... subscription model.      (Logo: http://photos.prnewswire.com/prnh/20140807/700645 ... for business innovations to make healthcare services more ...
(Date:7/30/2015)... DIEGO , July 30, 2015 /PRNewswire/ ... it has signed a definitive agreement to ... of non-invasive ventilation and sleep-disordered breathing medical ... clinical, innovation and market reputation in China, combined with ResMed,s global leadership in ... people in China ...
Breaking Medicine Technology:Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 2Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 3Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 4Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 5Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 6Magnaquest Signs a POC With a Leading Pharma Giant in Europe to Manage Subscription Management and Billing for Internet of Things (IoT) 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3
... Remedi SeniorCare®, one of the nation,s largest ... innovative solution for the long-term care industry -- ... long-term care facilities to more efficiently and ... This includes complex medication orders, electronic health ...
... 2012 Span-America Medical Systems, Inc. (NASDAQ:  SPAN) will ... conference call on Friday, February 3, 2012, covering results ... released after the regular close of trading the preceding ... call will be available online at www.spanamerica.com ...
Cached Medicine Technology:Connexit™ Launch Aims to Reshape Business of Long-Term Care 2Connexit™ Launch Aims to Reshape Business of Long-Term Care 3
Portex® pediatric tracheostomy tubes offer a choice in both form and fit. , ,The anatomical shape of the tube shaft along with the caudal angle of the 15 mm connector provide comfort and security...
... KIMBERLY-CLARK BALLARD Neonatal and ... is designed for intubated ... elbow design provide smooth ... port and locking thumb ...
KIMBERLY-CLARK BALLARD Neonatal and Pediatric TRACH CARE Manifold features lavage/irrigation port and locking thumb port. Multiple French sizes and packaging configurations. Gamma sterilized....
... Cuffed tubes include an ... holder, disconnect wedge, cleaning ... two inner cannulae., ... obturator, Velcro® trach tube ...
Medicine Products: