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VBI researchers develop new method for breast cancer biomarker discovery
Date:6/9/2009

certain cancer-related biological processes, such as cell proliferation, cell death, tumor development, and metastasis.

According to Lazar, "Assessing the changes in protein expression levels of these cells will help us better understand the complex biochemical signaling pathways involved in the development of cancer. We hope this will also shed some light on the ways that drugs like tamoxifen work to inhibit cell proliferation and to induce response to stress at the molecular level. This knowledge will help to advance our understanding of how breast cancer cells develop resistance to tamoxifen. In the long term, this should provide opportunities for the development of more effective diagnosis and treatments for cancer patients."

While the current research focuses more on the effectiveness of the method developed, the team plans to pursue more work using complementary techniques on biological replicates to confirm the differential expression of the proteins.


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Contact: Susan Bland
subland@vbi.vt.edu
540-231-7912
Virginia Tech
Source:Eurekalert

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