Navigation Links
Uterus Size May Predict Risk for Premature Twins After IVF
Date:7/10/2008

Evaluation may help select women who are at lower risk for complications, study suggests

THURSDAY, July 10 (HealthDay News) -- Measuring the height of the uterus of a women pregnant with twins after in vitro fertilization (IVF) can help determine her risk of having the babies born prematurely, a new report says.

Doing this using ultrasound can help doctors and women decide how many embryos should be transferred in one IVF attempt, according to the research, presented Wednesday at the European Society of Human Reproduction & Embryology annual meeting, in Barcelona, Spain.

"Twin pregnancies account for between a quarter and a third of pregnancies obtained during IVF, and 8 percent of them are complicated by the babies being born extremely premature, leading to medical complications and sometimes fetal mortality," presenter Raphael Hirt, a fellow in the Division of Reproductive Medicine at the Hospital Antoine Bclre in Paris, said in a news release from the European Society. "For this reason, single embryo transfer is promoted as the best way of avoiding twin pregnancies, but, in some cases, this can alter the overall likelihood of pregnancy. An evaluation of a woman's individual risk of perinatal adverse outcomes from a twin pregnancy may help to select those women who have a lower risk of having twins born severely prematurely and who could consider a double embryo transfer if that is what they want."

The researchers had previously observed that women who already had children were less likely to give birth prematurely. They theorized that this was because the uterine cavity had been distended by the previous pregnancies.

Using transvaginal ultrasound (a process called hysterosonometry, or HSM), they measured uterus height of 79 women and followed them after having successful IVF treatment.

Women with the smallest uteri (less that 63 millimeters high) had a much greater chance of having babies born severely premature with an increased number of fetal deaths -- seven fetal deaths in this group compared with one in the women with medium-size uteri (between 64 and 70 millimeters high) and none among those with uterus height greater than 70 millimeters. Six deaths in the small uteri group were linked to prematurity, while the one death in the mid-sized group was not.

After adjusting for any confounding factors such as age, parity, previous premature delivery, the researchers found a clear association with HSM.

"Our results show that HSM is a reliable and noninvasive method for predicting twin-related severe prematurity and neonatal mortality, and it can be used before conception to help with objective decision-making about the number of embryos to transfer," Hirt said. "For women with an HSM measurement of less than 62mm, a single-embryo transfer is indicated, but in those with a longer uterine cavity, a double-embryo transfer can be considered if it is acceptable to the patients."

The researchers plan to use their new criteria going forward and see whether it results in decreased fetal mortality. They also plan to study whether a short uterine cavity affects single pregnancies to find whether it can identify which women may need intensive neonatal care.

More information

The National Institute of Child Health and Human Development has more about fertility and infertility.



-- Kevin McKeever



SOURCE: European Society for Human Reproduction & Embryology, news release, July 8, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Removal of uterus increases risk of urinary incontinence
2. Research highlights problems of predicting birthweights in obese mothers
3. Single-nucleotide polymorphisms do not substantially improve risk prediction for breast cancer
4. Ankle-Arm Blood Pressure Test Predicts Heart Disease Risk
5. Thickness, Location Predict Skin Cancers Spread
6. New Method Better Predictor of In Vitro Fertilization Success
7. TB Outbreaks May Be Predicted by First 2 Cases
8. Elevated biomarkers predict risk for prostate cancer recurrence
9. ADHD Gene Doesnt Predict Response to Drugs
10. Cosmetic surgery procedures to exceed 55 million in 2015, ASPS study predicts
11. Simple ultrasound exam may predict osteoporosis risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers ... companies have a waiver for care if the client has a cognitive impairment diagnosis. ... pays for care, is often waived, so the benefits from their insurance start immediately,” ...
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/12/2017)... ... 2017 , ... First Healthcare Compliance (FHC), an industry leader ... range of technology and learning solutions at the 68th Annual American Healthcare Association ... held October 14–18, 2017 at the Mandalay Bay Resort in Las Vegas, Nevada. ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... products to meet the demand of today’s consumer and regulatory authorities worldwide. From ... probiotic experts and tested to meet the highest standard. , These products ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... 2017   West Pharmaceutical Services, Inc. (NYSE: ... drug administration, today shared the results of a study ... the intradermal administration of polio vaccines. The study results ... May 2017 by Dr. Ondrej Mach , Clinical ... Organization (WHO), and recently published in the journal ...
(Date:10/4/2017)... 4, 2017  According to the Centers for Disease Control and Prevention ... . PhysicianOne Urgent Care is helping communities across Massachusetts ... , by offering no-cost* flu shots through the end of the month. ... health insurance regulations. ... to get a flu shot is by the end of October, according ...
(Date:10/2/2017)... 2, 2017  AllianceRx Walgreens Prime, the combined central ... and pharmacy benefit manager Prime Therapeutics LLC (Prime), today ... included the unveiling of new signage at its headquarters ... as at a few other company-owned facilities across the ... patients, some of whom will begin to see the ...
Breaking Medicine Technology: