Navigation Links
Using synthetic evolution to study the brain: Researchers model key part of neurons
Date:10/2/2009

o make 100 more models. Thousands of generations later they get a model that matches the characteristics of the real thing. Researchers have used this technique in modeling before, but Kath and colleagues introduced a new twist: they allowed the structure of the model (not just its parameters) to be "mutated" during the "breeding".

"In the end, the computer found a quite simple state-dependent model for the sodium channels that provides a very accurate behavior on short time scales and out to several seconds, as well," Kath says. Their results were recently published in the Proceedings of the National Academy of Sciences.

Modeling of even this small a process is important, Spruston says, because it helps scientists understand the important details about how the brain works.

"We want to make sure we truly understand how these channels work by building a model that can recapitulate all the features we've observed," he says. "Making computer models is a way of identifying both what you understand and also where the gaps in your knowledge need to be filled. The cool thing is you're taking a page from a part of biology evolution and applying it to another part of biology neurobiology and using the computer in the middle."

The neurons the group studied are in the hippocampal region of the brain, which researchers have identified as being important for memory.

"If you want to understand how this neural circuit is processing information and memory, you have to understand how these neurons behave in different situations," Kath says. "If you leave out key details, you might miss something important."


'/>"/>

Contact: Kyle Delaney
k-delaney@northwestern.edu
847-467-4010
Northwestern University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Using Your Immune System to Fight Cancer
2. Teen attitudes toward smoking linked to likelihood of drinking and using drugs
3. Old Colony Elder Services Launches Supportive Housing Program in Plymouth
4. Analysis Shows Narrow Age Rating Would Raise Premiums by Nearly 50 Percent, Causing Many Young and Healthy to Forgo Coverage
5. Study looks at using the immune system to reduce prostate cancer risk
6. Louisiana's TCA Cellular Therapy's Findings Reported at World Stem Cell Summit -- Patients' Legs Saved from Amputation Using Adult Stem Cells
7. Heritage Provider Network and Dr. Richard Merkin Highlight Cutting Health Care Costs Using Electronic Medical Records
8. Florida Clinicians Now Delivering Non-Invasive Image-Guided Treatments Using Novalis Tx(TM) Radiosurgery Technology
9. Hormone promises to keep joint injuries from causing long-term osteoarthritis
10. UCSB researchers develop drug delivery system using nanoparticles and lasers
11. Using insects to test for drug safety
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... say that once the virus takes hold in any country ... // Officials admitted that they are facing an uphill battle ... easily from person to person, triggering a pandemic. ,The ... poultry, one of the most crowded places on earth and, ...
... Clark Gable's son has been exposed as a drug addict ... ,According to contactmusic.com, the daughter Kaylee feels that her grandfather ... his son, actor John Clark Gable, now. , ,She ... I know if my grandfather were alive today it would ...
... to new things and accepts them, although medical transcription is not ... records in papers and are not well stocked in most cases. ... records., ,In contrast, in the US, medical case files are ... industry in the US is well established. It is more than ...
... Fifteenth Annual Meeting and Clinical Congress to be held ... discuss important benefits //of vitamin D and the problems ... ,Vitamin D has been in the new recently and ... attributed to it. Recent studies have highlighted its deficiency ...
... researchers say that the distinctive features of the heart ... of a genetic quirk that is linked to a ... ,Steve Ommen, M.D., director of Mayo’s HCM Clinic ... said that the currently available test was only able ...
... Brachytherapy, which is touted as the best and latest ... Sydney's Mater Hospital Radiotherpahy Department.// ,It is ... set to improve results with fewer side effects. ... the southern hemisphere, bringing together image-enhancing technology that builds ...
Cached Medicine News:Health News:Rising in career top charts is Medical transcription 2
(Date:1/14/2014)... -- Luminex Corporation (Nasdaq: LMNX ) today announced ... quarter of 2013 on Monday, February 3, 2014. A ... after the close of trading. (Logo: ... conference call to discuss the operating highlights and financial ... December 31, 2013 on February 3, 2014, at 5:00 ...
(Date:1/14/2014)... -- Dynamic Healthcare Services, Inc. ("DHS"), a portfolio company of ... Home Medical Equipment, Inc. ("Progressive") of Clarion, PA ... acquisition were not disclosed. Progressive is a ... range of sleep, mobility, and respiratory products to customers in ... Pittsburgh markets. Progressive was founded in 2005 by ...
(Date:1/14/2014)... PLYMOUTH, Minn. , Jan. 14, 2014   NuAire ... for research, have come to agreement with Hitachi Koki ... service the Hitachi brand of centrifuges in North ... professionals throughout the United States and ... use, product benefits and features, options and accessories, training, pricing, ...
Breaking Medicine Technology:Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 2Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 3NuAire announces sales and service of Hitachi Koki centrifuges in North America 2
... U.S. Food and Drug Administration is warning the public ... law enforcement personnel as part of a continued international ... The criminals call the victims -- who ... or via "telepharmacies" -- and identify themselves as FDA ...
... EDDA Technology, a leading provider of advanced computer ... successful commercial installation of its IQQA®-Liver Enterprise product ... one of the top performing living donor liver ... use EDDA Technology,s IQQA®-Liver Enterprise in conjunction with ...
Cached Medicine Technology:FDA Warns Public of Continued Extortion Scam By FDA Impersonators 2FDA Warns Public of Continued Extortion Scam By FDA Impersonators 3EDDA Technology Successfully Installs IQQA®-Liver at Mayo Clinic in Arizona 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: