Navigation Links
Using microbubbles to improve cancer therapy
Date:4/24/2013

Microbubbles decrease the time and acoustic power of ultrasound required to heat and destroy an embedded target, finds research in BioMed Central's open access journal Journal of Therapeutic Ultrasound. If these results can be replicated in the clinic, microbubbles could improve the efficiency of high intensity ultrasound treatment of solid tumors.

High intensity ultrasound is already used to treat solid tumors. Ultrasound can be focused through soft tissue and, because it does not require probes or surgery, is non-invasive. However if the tumor is behind the ribcage or skull, the bone absorbs some of the ultrasound. Consequently the length of treatment needs to be increased, plus there is a potential for heat damage to the bone.

In order to improve ultrasound therapy, especially in these difficult to treat cases, a team from Boston University has developed phase shift nanoemulsions (PSNE), which produce tiny microbubbles when blasted with high intensity ultrasound. Microbubbles smaller than 200nm passively accumulate in tumors and this study shows that microbubbles of this size can amplify the effects of ultrasound in hydrogels designed to mimic solid tumors inside the body.

Holes formed in a predictable manner and with a predictable shape which altered with acoustic intensity. The acoustic intensity and exposure time required for thermal destruction of tumor tissue were both reduced by more than half, compared to ultrasound without microbubbles. The lower power levels and time needed to destroy a target in the presence of microbubbles could potentially improve cancer therapy, especially in hard to reach areas.

The first stage in any new treatment is to show safety and efficacy. Prof Tyrone Porter, who led this study explained, "We used PSNE of phospholipid coated perfluorcarbon which have no known toxicity and have already be shown to be safe clinically. Our technique pushes forward the possible applications of ultrasound therapy in treating solid tumors."

Open access publisher BioMed Central is proud to announce the launch of Journal of Therapeutic Ultrasound in partnership with the Focused Ultrasound Foundation and the International Society for Therapeutic Ultrasound.

"Focused ultrasound technology has enormous potential to improve the quality of lives for millions around the world," noted Neal F. Kassell, M.D., Chairman and Founder of the Focused Ultrasound Foundation. "The research reported in the Journal of Therapeutic Ultrasound will be central to advancing the field and will help accelerate the progress of focused ultrasound towards clinical adoption."


'/>"/>

Contact: Hilary Glover
hilary.glover@biomedcentral.com
44-020-319-22370
BioMed Central
Source:Eurekalert

Related medicine news :

1. MU receives national award for using mind-body approach to improve health
2. More Teen Girls Using Contraceptives: CDC
3. Using Earplugs Eases ICU Patients Confusion: Study
4. 16 years old is peak risk for teens misusing prescription drugs
5. Kids Most Likely to Start Abusing Painkillers at 16: Study
6. Breathing during radiotherapy - how to hit the treatment target without causing collateral damage
7. Report using private health claims data shows prices are driving health spending growth
8. Type of viral infection of eye associated with disease causing blindness in the elderly
9. Hepatitis C Causing Liver Damage in Greater Numbers: Study
10. Pivotal role for proteins -- from helping turn carbs into energy to causing devastating disease
11. Population displacement during disasters predicted using mobile data
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Planet Fitness, ... the U.S., announced today its plans to open a flagship location in Covington, LA ... the former Rooms To Go store next to Office Depot in the Holiday Square ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of ... Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, ... In honor of Morris F. Collen, a pioneer in the field of medical informatics, ...
(Date:10/12/2017)... LOS ANGELES (PRWEB) , ... October 12, 2017 ... ... of Parsa Mohebi Hair Restoration, has recently contributed a medical article to the ... doctors, on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... FL (PRWEB) , ... October 12, 2017 , ... On ... holding a treadmill relay – Miles by Moonlight to raise money for the American ... $300 or more. , Teams will work together to keep their treadmills moving ...
(Date:10/12/2017)... ... 12, 2017 , ... In the United States, single-family home ... states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average is ... low property-tax rates, which contributes to the relatively lower cost of living in ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... West Pharmaceutical Services, Inc. (NYSE: ... drug administration, today announced that it will release third-quarter ... October 26, 2017, and will follow with a conference ... 9:00 a.m. Eastern Time. To participate on the call, ... ID is 94093362. ...
(Date:10/10/2017)... Oct. 10, 2017  NDS received FDA 510(k) clearance in May ... battery-powered display stand specifically designed for endoscopy environments. An innovative secondary ... a clinical solution to support the improvement of patient outcomes, procedural ... ... ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017  According to the Centers for ... the end of October . PhysicianOne Urgent Care is helping communities across ... Westchester, NY , by offering no-cost* flu shots through the ... as mandated by certain health insurance regulations. ... The best time to get a flu shot is by the ...
Breaking Medicine Technology: