Navigation Links
Using cassava to address vitamin A deficiency
Date:10/4/2010

The roots of cassava (Manihot esculenta) serve as the primary source of carbohydrates in the diets of people in many arid regions of the world, including more than 250 million people in sub-Saharan Africa. Unfortunately the roots of commercial cassava cultivars are quite low in micronutrients, and micronutrient deficiencies are widespread in these regions. In addition to programs designed to deliver vitamin supplements, there has been considerable effort aimed at biofortification; that is, increasing the amounts of available micronutrients in staple crops such as cassava. An article published in The Plant Cell this week describes the results of a collaborative effort led by Professor Peter Beyer from Freiberg University in Germany, together with researchers at the International Center for Tropical Agriculture (CIAT) in Colombia. These researchers studied a naturally arising variant of cassava with yellow roots in order to understand the synthesis of provitamin A carotenoids, dietary precursors of vitamin A. Beyer was also co-creator of Golden Rice, a biofortified crop which provides precursors of vitamin A not usually present in the rice that people eat.

In this work, the scientists compared different cassava cultivars with white, cream, or yellow roots more yellow corresponding to more carotenoids in order to determine the underlying causes of the higher carotenoid levels found in the rare yellow-rooted cassava cultivar. They tracked the difference down to a single amino acid change in the enzyme phytoene synthase, which functions in the biochemical pathway that produces carotenoids. The authors went on to show that the analogous change in phytoene synthases from other species also results in increased carotenoid synthesis, suggesting that the research could have relevance to a number of different crop plants. Furthermore, they were able to turn a white-rooted cassava cultivar into a yellow-rooted plant that accumulates beta-carotene (provitamin A) using a transgenic approach that increased the enzyme phytoene synthase in the root.

This work beautifully combines genetics with biochemistry and molecular biology to deepen our understanding of carotenoid biosynthesis. "It paves the way for using transgenic or conventional breeding methods to generate commercial cassava cultivars containing high levels of provitamin A carotenoids, by the exchange of a single amino acid already present in cassava" says Beyer. Thus, it has the potential be a big step the battle against vitamin A deficiency, which is estimated to affect approximately one third of the world's preschool age children.


'/>"/>

Contact: Nancy Hofmann
nhofmann@aspb.org
575-571-8926
American Society of Plant Biologists
Source:Eurekalert  

Related medicine news :

1. Ecumen Building Senior Housing in Apple Valley, Minnesota and Will Manage New Maplewood, Minnesota Property
2. Using gold nanoparticles to hit cancer where it hurts
3. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
4. Register Online for this Year's Horst Senior Living Conference on April 8 Featuring Keynote Speaker and Senior Housing Expert Jim Moore
5. Rockland County Landlord Agrees to Settlement With United States to Protect Fair Housing Rights of Tenants With Mental Disabilities
6. Groundbreaking Study Using Ultrasound for the Treatment of Intracerebral and Intraventricular Hemorrhage Stroke Shows Promise
7. SDI Reports: Nearly a Third Of Physicians Use Handheld and Smartphone Devices to Access Medical Information - Physicians Most Likely to be Using Apple iPhone
8. Parrish Medical Center Sees 30 Percent Improvement in Mortality Using Real-Time Clinical Surveillance Solution from Thomson Reuters
9. Family history is strong predictor of obstructive coronary artery disease using CCTA
10. Using new approach, Mayo Clinic researchers find level of gene alters risk of Alzheimers disease
11. Best Selling, Non Toxic Skin Brightener Does the Job Using Safe, Healthy Ingredients and Introduces New Anti Aging Ingredients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Using cassava to address vitamin A deficiency
(Date:8/16/2017)... ... August 16, 2017 , ... Ten outstanding teachers in the Greater Houston area ... will win a visit by a Houston Texans player, two tickets to a Texans ... years old can visit texanschecking.com/stars to nominate their favorite teacher with an essay of ...
(Date:8/16/2017)... Georgia (PRWEB) , ... August 16, 2017 , ... ... in Atlanta, opened their doors. They celebrate 30 years in business this year, ... create an up-to-date, inviting, tranquil space to serve their patients. , It ...
(Date:8/16/2017)... ... August 16, 2017 , ... Maury Regional Health has announced ... draws. By broadly deploying AccuVein devices, Maury Regional Medical Center is making vein visualization ... out of a needle stick and more importantly, helps our staff members locate a ...
(Date:8/16/2017)... ... 2017 , ... A global leader in the treatment of clubfoot, CURE ... Indian states—bringing the country one step closer to eliminating clubfoot as a lifelong disability ... on track to enroll 10,000 children in the clubfoot treatment program in this year ...
(Date:8/16/2017)... ... ... Fusion Flix Inc., a Telly Award Winning, Non Profit Corporation has announced their ... a partnership with the Amazon Video Direct Streaming Distribution Platform. , Their content will ... in 2018. Proceeds will be going to further health research. , Fusion Flix ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... -- Axium Pharmaceuticals Inc., the creator of the drug Truveta for ... of an IPO. The United States ... of a prescription epilepsy drug being $450.00-$1200.00 for a one month supply. ... AXIUM PHARMACEUTICALS, INC ... staggering figure is the fact that Americans spent $42 billion on anxiety ...
(Date:8/14/2017)... Israel , Aug. 15, 2017  BrainStorm ... adult stem cell technologies for neurodegenerative diseases, announced financial ... "We are in ... 3 trial to investigate NurOwn ® in ALS," ... Officer of BrainStorm. "We have agreements with Mass. General ...
(Date:8/8/2017)... 8, 2017  BioLineRx Ltd. (NASDAQ/TASE: BLRX), a clinical-stage ... its financial results for the second quarter ended June ... second quarter 2017 and to date: ... programs for the Company,s lead project, BL-8040: ... with BL-8040 as novel stem cell mobilization treatment for ...
Breaking Medicine Technology: