Navigation Links
Using a small stockpile of a secondary antiviral drug in a flu pandemic
Date:4/30/2009

In a global influenza pandemic, small stockpiles of a secondary flu medication if used early in local outbreaks could extend the effectiveness of primary drug stockpiles, according to research made available today ahead of publication in PLoS Medicine.

Many countries are investing in large stockpiles of a single drug, oseltamivir (Tamiflu). But influenza viruses can become resistant to antiviral drugs, and the widespread use of a single drug is likely to increase the risk that a resistant strain will emerge. If such a strain were to spread widely, the effectiveness of antiviral drugs in treating infected patients, as well as their ability to slow the spread of a pandemic, would be greatly reduced.

Using a mathematical model to represent the global spread of pandemic influenza, an international team of researchers led by Joseph Wu of the University of Hong Kong, and including collaborators in the UK and the US, found that treating as few as only the first 1% of the population in a local epidemic with a secondary drug rather than with oseltamivir, could substantially delay the development of resistance to oseltamivir. This reduction in resistance was predicted to benefit not only local populations, but also those in distant parts of the world where the pandemic would subsequently spread through air travel.

In the context of the currently emerging swine flu, the secondary drug could be zanamivir (Relenza), the only other approved drug to which the new H1N1 strain has been found to be susceptible.

This strategy is predicted to be effective because it delays use of the primary stockpiled drug until a certain proportion of the local population (about 1.5% according to the model) has been infected with virus that remains susceptible to the primary drug. With drug-sensitive virus in the majority as people recover from infection and develop immunity, only a minority of further infections are likely to be resistant to the p
'/>"/>

Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers to Monitor Public Perception of Swine Flu Outbreaks Using Technology from Realtime Search Engine, OneRiot
2. New Medical Study Establishes First-Ever Long-Term Benefits for Macular Degeneration Sufferers Using Macular Health Vitamin Supplement
3. WaferGen and Leading Academic Medical Center Establish Genotyping Research Collaboration to Validate SNPs in Breast Cancer Using SmartChip(TM) Real-Time PCR System
4. Kaiser Family Foundation Launches Daily Global Health Policy Report and Policy Tracking Tool As Part of New Web Gateway Focusing on U.S. Global Health Policy
5. Movero Delivers Over 10,000 Training Sessions for Physicians Using Mobile ePrescription Applications
6. Early-stage lung cancer identified using computer-aided system
7. Three Million People Now Using Kaiser Permanentes Personal Health Record
8. Worlds First Disposable Wireless RFID Sensor Detects Radiation Threats in Shipping Containers Using Modified Cell Phone Technology
9. Using tools requires that the brain is able to control movements
10. Yashoda Cancer Institute Treats First Patient in India Using RapidArc Radiotherapy Technology
11. Using Public Relations to Launch, Grow and Extend Your Brands
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... Fe, New Mexico (PRWEB) August 31, 2014 ... a Disability Rights friend-of-the-court brief in support of the ... district court ruling that the New Mexico constitution contains ... No. 33,630, Court of Appeals of the State of ... joined in the brief: ADAPT, the American Association ...
(Date:8/31/2014)... 31, 2014 Kicking blog MichaelHusted.com ... Nelson of Matt Nelson Kicking Academy on his role ... being a National Camp Series (NCS) Associate according to ... "Matt Nelson is another high quality to our NCS ... coaching. He is an outstanding pro prospect kicker, ...
(Date:8/31/2014)... 31, 2014 The severity of menopausal ... specializing in menopause is expert in helping patients ... relief from uncomfortable symptoms with the latest treatment options, ... offer a variety of alternative treatments and products that ... treatment options may fall outside of what can be ...
(Date:8/30/2014)... 2014: A new method to predict the optimal ... presented at ESC Congress today by Dr Benjamin Dahan ... 350 AEDs located in public places for optimal prevention ... Dahan said: "Out of hospital cardiac arrest is a ... between 50 and 100 per 100 000 in the ...
(Date:8/30/2014)... August 31, 2014 According to the latest ... by step holistic system for skin health. It seems that ... been tried by more than 138,000 patients from all over ... Walden, who says that this method will not only eliminate ... skin. , What makes this program unique among other ...
Breaking Medicine News(10 mins):Health News:Not Dead Yet and Six Other National Disability Groups Submit Friend-of-the-Court Brief in New Mexico Assisted Suicide Appeal 2Health News:Not Dead Yet and Six Other National Disability Groups Submit Friend-of-the-Court Brief in New Mexico Assisted Suicide Appeal 3Health News:MichaelHusted.com Features an Interview with Matt Nelson of Matt Nelson Kicking Academy on His Role as a Kicking Coach and on Becoming a National Camp Series Associate 2Health News:MichaelHusted.com Features an Interview with Matt Nelson of Matt Nelson Kicking Academy on His Role as a Kicking Coach and on Becoming a National Camp Series Associate 3Health News:A Look at Complementary Therapies and Alternative Medicine for National Menopause Awareness Month 2Health News:A Look at Complementary Therapies and Alternative Medicine for National Menopause Awareness Month 3Health News:A Look at Complementary Therapies and Alternative Medicine for National Menopause Awareness Month 4Health News:A Look at Complementary Therapies and Alternative Medicine for National Menopause Awareness Month 5Health News:New method predicts optimal number and location of AEDs 2Health News:Acne No More Review Reveals Unusual Tip to Eliminate Acne Permanently 2
... NEW YORK, Feb. 26 With sensational headlines about multiple ... fact that infertility is a painful reality for many couples ... million Americans struggle with fertility issues, and the number is ... has doubled in size and now exceeds $3 billion. ...
... As the voice of the global clinical ... (ACRO) had the honor of presenting before the ... 2009 in Tokyo. ACRO Chair Derek Winstanly, MBChB, ... ACRO Executive Director Douglas Peddicord, Ph.D. addressed "Representing ...
... number of potential medicines to treat heart disease and ... by the Pharmaceutical Research and Manufacturers of America (PhRMA) ... medicines to treat these diseases currently are being tested ... the U.S. Food and Drug Administration, compared to 146 ...
... Secure Message Capability to Facilitate Instant Collaborative ... Science, Inc. (HSI), a Rockville Innovation Center ... an innovative software service that enables physicians ... a secure environment. PatientCarenet.Org connects community-based ...
... as keys to successLAS VEGAS, Feb. 26 The ... ) (AAOS) is honored to recognize a surgeon who has ... backgrounds to pursue the orthopaedic specialty and who has never ... presented today with the Academy,s Diversity Award at its 2009 ...
... first considered a life in medicine at the ripe old ... and tribulations of a young television doctor named Ben Casey. ... sparked an idea which led to an impressive and successful ... Zuckerman was named President of the American Academy of ...
Cached Medicine News:Health News:A Recession-Resistant Business? Introducing FertilityAuthority.com 2Health News:ACRO Presents at Japan CRO Association Commemorative Symposium 2Health News:Record Number of Innovative New Medicines for Heart Disease and Stroke Now in Development 2Health News:Record Number of Innovative New Medicines for Heart Disease and Stroke Now in Development 3Health News:Human Science, Inc. Launches PatientCarenet.Org 2Health News:Human Science, Inc. Launches PatientCarenet.Org 3Health News:Ramon L. Jimenez, MD: A Diverse Life 2Health News:Ramon L. Jimenez, MD: A Diverse Life 3Health News:Joseph D. Zuckerman, M.D., Elected President of the American Academy of Orthopaedic Surgeons 2Health News:Joseph D. Zuckerman, M.D., Elected President of the American Academy of Orthopaedic Surgeons 3
(Date:8/29/2014)... DUBLIN , Aug. 29, 2014 ... the "Global Peptide Cancer Therapeutics Market & Pipeline ... The conventional methods developed to prevent and eradicate ... cancer treatment. These methods are confined to low specificity, ... the researchers to look for a better solution. It ...
(Date:8/29/2014)... 29, 2014 According to ... by Extraction type (SFE, Cold Pressed, Organic Solvent, & ... Pharmaceutical, Food Supplements, Fragrance, & Others) - Global Trends ... and segments the Amaranth Seed Oil Market with ... in terms of value. The Amaranth Seed Oil ...
(Date:8/29/2014)... , Aug. 29, 2014 Research ... "Research and Development Trend Forecast of Pharmaceutical Equipment ... Research and Development Trend Forecast of ... 2014-2018 mainly analyzes China,s pharmaceutical ... supply & demand, competition landscape, and business performance of ...
Breaking Medicine Technology:Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2Amaranth Seed Oil Market worth $700.6 Million by 2019 2Amaranth Seed Oil Market worth $700.6 Million by 2019 3Amaranth Seed Oil Market worth $700.6 Million by 2019 4Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2
... 10, 2011 Amgen today announced that five inspirational cancer survivors ... their communities have been selected as Breakaway from Cancer ... The five Breakaway from Cancer Champions were ... this year. The 2011 Breakaway from Cancer Champions are: ...
... COLUMBUS, Ohio, May 10, 2011 Taylor Strategy Partners (TSP), who ... the best human capital for their organizations, is pleased to announce ... TSP was founded in 1969 and is headquartered in Columbus, OH ... Radloff, TSP Vice President and Managing Director, will be taking the ...
Cached Medicine Technology:Five Californians Selected as Breakaway from Cancer® Champions to be Honored During Amgen Tour of California 2Five Californians Selected as Breakaway from Cancer® Champions to be Honored During Amgen Tour of California 3Five Californians Selected as Breakaway from Cancer® Champions to be Honored During Amgen Tour of California 4Taylor Strategy Partners Set to Open Office in Kansas City in June 2011 2
Instrument necessary for insertion of Ritleng Bicanaliculus systems and of Self-Threading Monoka systems....
... For canalicular laceration or ... silicone and Stainless Steel Probe. ... Tubing securely swaged into malleable ... anchored by punctum plug: no ...
Recommended to insert plug portion of all monocanalicular intubation systems into punctum....
Skin Tone External Eyelid Weights...
Medicine Products: