Navigation Links
Using Viagra to combat malignant melanoma
Date:11/8/2011

ce, which is better known under its trade name, Viagra, had already been reported to improve tumor immunity in experimental animal models several times before. Of the mice that had been given the substance with their drinking water, more than twice as many were still alive after about seven weeks as of their untreated fellows. In the animals that had been treated, both the number of tumor-specific T cells and the level of activating molecules had returned to normal. This means that sildenafil successfully neutralizes the chronic inflammation in the melanoma environment and combats the immunosuppressive activity of MDSC.

"Our research approach is special because the disease takes a very similar course in mice as melanoma does in humans," Viktor Umansky said explaining the medical relevance of his findings. "Therefore, it is very well possible that sildenafil can also inhibit the immunosuppressive effects of inflammation and thus improve antitumor immunity in people with melanoma. In this way, the drug may contribute to achieving better treatment results in malignant melanoma."


'/>"/>
Contact: Dr. Sibylle Kohlstdt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related medicine news :

1. More People Landing in the ER After Abusing Muscle Relaxant: Report
2. NYUCD awarded $2.2 million NIH grant to decode genome of caries-causing bacteria
3. Using Drug for Prevention Might Help in Hard-to-Treat Hemophilia
4. Team discovers how a cancer-causing bacterium spurs cell death
5. High tech detection of breast cancer using nanoprobes and SQUID
6. Mayo Clinic study guides physicians using therapeutic cooling to treat cardiac arrest patients
7. First report of increased safety using simultaneous techniques for cardiac testing published
8. More Teen Males Using Condoms When They First Have Sex: Survey
9. Molecular depth profiling modeled using buckyballs and low-energy argon
10. Infusing chemotherapy into the liver gives extra months of disease-free life in melanoma patients
11. Bed Bug Insecticides Causing Sickness, Officials Warn
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2015)... 2015 SpineFrontier, a Less Exposure Surgery ... to produce and market their new sacroiliac joint fusion ... in outpatient settings and is compatible with both lateral ... has been extensively researched and refined by SpineFrontier, the ... this approach in conjunction with a sacroiliac joint fusion ...
(Date:5/2/2015)... 02, 2015 Ticket Down has secured additional ... the long awaited event today, Saturday, May 2nd at the ... fans will be able to secure tickets for both the ... that boxing fans have wanted for more than five years ... “Money” Mayweather will step inside the ring to fight Manny ...
(Date:5/2/2015)... May 02, 2015 It’s a pattern ... natural disaster strikes anywhere on this planet, cyber scammers ... sympathy and compassion for their own personal gain. ... Emergency Readiness Team) issued an alert titled “Nepal ... email scams citing the earthquake in Nepal. The scam ...
(Date:5/2/2015)... IL (PRWEB) May 02, 2015 Kare Visits ... provide support for busy caregivers. Kare Visits offers relief ... and assisted living facilities. According to the Caregiver ... spend an average of 20 hours a week caring for ... of the cost to hire a nurse, a caregiver is ...
(Date:5/1/2015)... Frisco, Texas (PRWEB) May 02, 2015 ... Frisco, Texas, is proud to announce the addition of ... Jen Widerstrom is a life long athlete, growing up ... fitness passion after college by becoming a personal trainer ... since been the face of several TV shows highlighting ...
Breaking Medicine News(10 mins):Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 2Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 3Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 3Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 4Health News:Chicagoan Seeks to Transform Industry by Launching an Innovative Elderly Care Solution 2Health News:IDLife LLC Announces New Partnership with Fitness Celebrity, Jen Widerstrom 2
... oil spill along the United States Gulf Coast poses health ... communities, according to a new commentary by UCSF researchers who ... to look into health problems caused by the oil spill. ... of the risk factors, coastal air quality, is improving now ...
... dependent a man is on his female partner, the more ... to be presented at the 105th Annual Meeting of the ... to have the opposite effect: the more dependent they are ... engage in infidelity," said Christin Munsch, a sociology Ph.D. candidate ...
... BOSTON, Mass. (August 12, 2010) Once thought to be a ... cause of death and disability,in poorer countries. Almost two-thirds of ... and middle-income countries. A paper to be published online ... the international community must now discard the notion that cancer ...
... Facial pain. Nasal congestion. Postnasal drip. Fatigue. ... tissue in the nasal and sinus cavity. The illness strikes ... top five reasons patients visit their primary care doctor. Treating ... if the cause is viral or bacterial. Unfortunately little ...
... Gardner HealthDay Reporter , WEDNESDAY, Aug. 11 ... deep brain stimulation appeared to improve memory slightly in ... caution that the findings are very preliminary and that ... study. However, test results and brain imaging suggest that ...
... HealthDay Reporter , FRIDAY, Aug. 13 (HealthDay ... take acetaminophen, best known as Tylenol, were more than ... never take the over-the-counter pain and fever reducer, new ... an increased chance of eczema and rhinoconjunctivitis, or allergic ...
Cached Medicine News:Health News:Health impact of Gulf Coast oil spill hazardous but improving 2Health News:Health impact of Gulf Coast oil spill hazardous but improving 3Health News:Men more likely to cheat if they are economically dependent on their female partners 2Health News:Global health leaders advocate for expanding cancer care in developing countries 2Health News:Global health leaders advocate for expanding cancer care in developing countries 3Health News:Primary care doctors get little information about chronic sinusitis 2Health News:Deep Brain Stimulation Studied for Alzheimer's 2Health News:Deep Brain Stimulation Studied for Alzheimer's 3Health News:Tylenol Use Linked to Asthma, Other Allergies in Teens 2Health News:Tylenol Use Linked to Asthma, Other Allergies in Teens 3Health News:Tylenol Use Linked to Asthma, Other Allergies in Teens 4
(Date:4/30/2015)... April 30, 2015 /PRNewswire/ - Pivotal Therapeutics Inc. ... with a focus on Omega-3 therapies for cardiovascular ... highlights and financial results for the fiscal year ... herein are in Canadian dollars unless otherwise stated. ... significant, with the right strategic partners and additional ...
(Date:4/30/2015)... -- Omnicell, Inc. (NASDAQ: OMCL ), a leading provider ... today announced results for its first quarter ended March ... first quarter of 2015 was $116.2 million, up $14.5 ... and down $5.3 million or 4.4% from the fourth ... income as reported in accordance with U.S. generally accepted ...
(Date:4/30/2015)... MOUNTAIN VIEW, Calif. , April 30, 2015 /PRNewswire/ ... it will release its first quarter 2015 financial results ... 2015.   In conjunction with the release, the Company ... at 5:00 p.m. Eastern Time on ... of the quarter and other business developments. ...
Breaking Medicine Technology:Pivotal Therapeutics Announces 2014 Financial Results 2Pivotal Therapeutics Announces 2014 Financial Results 3Pivotal Therapeutics Announces 2014 Financial Results 4Pivotal Therapeutics Announces 2014 Financial Results 5Pivotal Therapeutics Announces 2014 Financial Results 6Omnicell Announces First Quarter 2015 Results 2Omnicell Announces First Quarter 2015 Results 3Omnicell Announces First Quarter 2015 Results 4Omnicell Announces First Quarter 2015 Results 5Omnicell Announces First Quarter 2015 Results 6Omnicell Announces First Quarter 2015 Results 7Omnicell Announces First Quarter 2015 Results 8Omnicell Announces First Quarter 2015 Results 9Omnicell Announces First Quarter 2015 Results 10Omnicell Announces First Quarter 2015 Results 11Omnicell Announces First Quarter 2015 Results 12Omnicell Announces First Quarter 2015 Results 13Omnicell Announces First Quarter 2015 Results 14Omnicell Announces First Quarter 2015 Results 15Omnicell Announces First Quarter 2015 Results 16Omnicell Announces First Quarter 2015 Results 17Omnicell Announces First Quarter 2015 Results 18Omnicell Announces First Quarter 2015 Results 19Omnicell Announces First Quarter 2015 Results 20Omnicell Announces First Quarter 2015 Results 21Omnicell Announces First Quarter 2015 Results 22Omnicell Announces First Quarter 2015 Results 23Omnicell Announces First Quarter 2015 Results 24Omnicell Announces First Quarter 2015 Results 25Omnicell Announces First Quarter 2015 Results 26Omnicell Announces First Quarter 2015 Results 27IRIDEX Announces First Quarter 2015 Conference Call and Release Date 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: