Using HEPA filters may improve cardiovascu... (general improvement in the function of t...)

Using HEPA filters may improve cardiovascular health

Date:2/15/2008

general improvement in the function of the inner lining of small vessels, including those supplying the heart, said Dr. Loft.

The researchers found that HEPA filtration removed about 60 percent of the ultrafine, fine and coarse air particles in homes, and was associated with an 8.1 percent improvement in individual MVF.

We expected that removing air particles with the HEPA filters would result in improvement of MVF but we were heartened and surprised by the extent it did, considering the modest levels of particles in the indoor air of the homes of the elderly, said Dr. Loft.

None of the secondary endpoints considered showed significant differences after statistical corrections, suggesting that the mechanism underlying the improvement in MVF after air filtration remains unclear, and underscoring the need for further study.

The results of this study indicate that reduction of particles in recirculated indoor air by filtration significantly improves MVF in a healthy, non-smoking, elderly population, wrote Dr. Loft. The improvement could not be ascribed to significant reduction in inflammation or oxidative stress by means of biomarkers.

Dr. Loft and his team are now studying the effect of high levels of wood smoke on MVF in healthy subjects. They hope that the mechanisms can be better understood by means of a wider range of secondary endpoints, including expression of important genes, which they are currently developing.

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Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

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