Navigation Links
Using HEPA filters may improve cardiovascular health
Date:2/15/2008

One day doctors may recommend using high efficiency particle air (HEPA) filters along with weight loss, smoking cessation, and exercise to improve cardiovascular health, according to researchers in Denmark. In a recent study, they found that using HEPA filters for just two days significantly improved a key measure of cardiovascular health in healthy, non-smoking elderly individuals.

Reduction of particle exposure by filtration of recirculated air for only 48 hours improved the microvascular function (MVF) in healthy elderly citizens, said Professor Steffen Loft, M.D., D.M.Sc., of the Institute of Public Health in Copenhagen. This suggests that indoor air filtration represents a feasible means of reducing cardiovascular risk. Abnormal function of the inner lining of small vessels is known to be a predictor of dangerous or possibly fatal cardiovascular events.

The study was published in the second issue for February of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

The researchers measured MVF and ambient airborne particles in the homes of 21 non-smoking couples aged 60-75 who lived close to heavily trafficked roads. Each couple used air purifiers for two 48-hour periods. During one period, the purifier was equipped with a HEPA filter, and during the other, it ran without it, so that each individual served as his or her own control. The size distribution and number concentration of indoor air particles in each home were continuously monitored.

The researchers then assessed each individuals MVF using a noninvasive finger sensor. Several secondary endpoints were studied in blood and urine samples to assess possible mechanisms of action: markers of inflammation, hemostasis, and oxidative stress.

Our main finding was a significant improvement in the function of small finger blood vessels after reduction of indoor air particles. This effect most likely indicates a general improvement in the function of the inner lining of small vessels, including those supplying the heart, said Dr. Loft.

The researchers found that HEPA filtration removed about 60 percent of the ultrafine, fine and coarse air particles in homes, and was associated with an 8.1 percent improvement in individual MVF.

We expected that removing air particles with the HEPA filters would result in improvement of MVF but we were heartened and surprised by the extent it did, considering the modest levels of particles in the indoor air of the homes of the elderly, said Dr. Loft.

None of the secondary endpoints considered showed significant differences after statistical corrections, suggesting that the mechanism underlying the improvement in MVF after air filtration remains unclear, and underscoring the need for further study.

The results of this study indicate that reduction of particles in recirculated indoor air by filtration significantly improves MVF in a healthy, non-smoking, elderly population, wrote Dr. Loft. The improvement could not be ascribed to significant reduction in inflammation or oxidative stress by means of biomarkers.

Dr. Loft and his team are now studying the effect of high levels of wood smoke on MVF in healthy subjects. They hope that the mechanisms can be better understood by means of a wider range of secondary endpoints, including expression of important genes, which they are currently developing.


'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. Using coxibs and NSAIDs to treat osteoarthritis
2. Adverse housing conditions contribute to diabetes risk
3. Females avoid incest by causing male relatives to leave home
4. Are Bargaining Groups Hired by Independent Drugstores Causing Payment Delays to Pharmacies?
5. University of Nevada School of Medicine Professor Confirms Accuracy Through Validation Study Using the CSI Health Station Model 6K
6. National Council of Negro Women (NCNW) Partners With Sherwin-Williams to Target Lead Risks in Neglected Housing
7. Using the Internet to Promote Exercise
8. Hazards of using crib bumper pads outweigh their benefits
9. Nosespray vaccine using aloe vera has exciting potential, researcher says
10. Patient Safety Authority Releases Advisory Focusing on Common Causes of Medication Errors
11. Genetic test announced for suicidal ideation in patients using antidepressant drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... , ... “The Adventures of Joey, The Dog Who Barks at Puddles”: a ... to the fullest, as God intended. “The Adventures of Joey, The Dog Who Barks ... pursuing her passion for writing, especially about truth and human behavior. , Published by ...
(Date:3/23/2017)... ... March 23, 2017 , ... The physicians of KSF Orthopaedic Center ... Houston Area. The new location is located at 2255 E. Mossy Oaks Rd., Suite ... This newest location will provide patients living in the north Houston area (The Woodlands, ...
(Date:3/23/2017)... ... March 23, 2017 , ... PAINWeekEnd (PWE) Oklahoma City, ... Broadway Avenue, will be an educational and exciting program providing busy clinicians and ... of chronic pain. , Oklahoma is in a healthcare crisis. The state ranks ...
(Date:3/23/2017)... ... ... 82% of adults are unaware of the dangers that infectious bacteria play in mouth disease, ... times a day that dentists recommend. The ramifications of improper oral upkeep go far beyond ... missing 164 million hours of work each year due to dental issues. That is why ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... ... release of SmartBen NOW, an innovative mobile app and centralized benefits dashboard solving ... present critical information securely from multiple locations. For the first time, employees can ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , Mar 24, 2017 Research and Markets ... Discovery and Diagnostics, 2017 - 2035" report to their offering. ... The Deep Learning: ... and future outlook of the growing market of deep learning solutions ... deep learning algorithms have emerged as a novel solution to generate ...
(Date:3/24/2017)... , Mar 24, 2017 Research and Markets ... Global Strategic Business Report" report to their offering. ... The report provides separate comprehensive analytics for ... Europe , Asia-Pacific , ... are provided for the period 2015 through 2022. Also, a six-year historic ...
(Date:3/24/2017)... 2017  Mirabilis Medical, a Seattle ... non-invasive surgery, announced today CE Mark authorization for ... uterine fibroids throughout the European Union.  The company ... the US Food and Drug Administration to begin ... the United States.  The Mirabilis System combines high-speed ...
Breaking Medicine Technology: