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Use of lubricants with anal sex could increase risk of HIV
Date:5/25/2010

ase III trial of PrEP involving men who have sex with men in South America, Africa and the United States is expected to report results by early next year. Yet, if either of these approaches is found effective in clinical trials, they will do no good if those most at risk don't use them. Other research presented today sheds light on this issue. Summaries of all three studies are provided below.

M2010 is taking place May 22-25 at Pittsburgh's David L. Lawrence Convention Center. Nearly 1,000 participants from 47 different countries are attending the meeting to hear about the latest developments in HIV prevention research.

Use of lubricants with anal sex associated with more rectal STIs

Lubricants are typically used before and during receptive anal intercourse, but their use could increase the risk of rectal sexually transmitted infections (STIs), a study involving nearly 900 men and women in Baltimore and Los Angeles has found. Even after controlling for gender, HIV status, city, condom use, and number of sex partners in the past month, the association between lubricant use before receptive rectal intercourse and rectal STIs remained strong, reported Pamina Gorbach, Dr.PH, from the School of Public Health and the David Geffen School of Medicine at the University of California, Los Angeles, who led the study. According to the study's statistical analysis that considered the HIV status, gender, condom use and study site, participants who used lubricants before receptive anal intercourse were three times more likely to have a rectal STI. Although the analysis didn't consider the specific lubricants being used, it may be that certain types of products are more irritating to the lining of the rectum than others, which could increase men and women's vulnerability to rectal STIs, the researchers suggest.

The study, which was conducted between October 2006 and December 2008, examined the rectal health and behaviors of 879 men and w
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Contact: Lisa Rossi
rossil@upmc.edu
412-916-3315
Microbicides 2010 (International Conference on Microbicides)
Source:Eurekalert

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