Navigation Links
Use of frozen material for fecal transplant successfully treats C. difficile infection
Date:4/23/2014

in check.

FMT probably treats C. difficile by restoring the normal balance of intestinal microbes. Previous animal and human FMT studies using fresh fecal material have had success rates of around 90 percent, but the MGH researchers note that recruiting and screening potential donors can be time-consuming and costly. Banking a supply of frozen, prescreened donor stool could significantly increase the availability of FMT, and the current study was designed to test the feasibility and effectiveness of such an approach, along with comparing two routes for delivery of the donor material.

Stool samples were donated by exceptionally healthy adults who received comprehensive screening for infectious diseases. Donors also were asked to refrain from eating any common allergens, such as nuts or eggs, in the days before donation. The donated fecal material was filtered, diluted, screened and frozen; stored for at least four weeks to allow retesting donors for any hidden infections; and prior to administration, thawed and kept refrigerated.

The study enrolled 20 patients three of whom were children who either had three or more episodes of mild to moderate C. difficile infection for which antibiotic treatment failed or had two episodes serious enough to require hospitalization. Participants were randomly divided into two groups 10 who received donor material by standard colonoscopy and 10 who received it though a nasogastric tube (NGT) passed into the stomach. A single administration was successful in curing 14 of the 20 participants 8 in the colonoscopy group and 6 in the NGT group, a difference not considered significant in such a small study.

Among those whose infections did not resolve, a single participant declined additional treatment. The other 5 received a second administration, which cured the infection in 4, for an overall success rate of 90 percent, similar to that of the previous studies. Partici
'/>"/>

Contact: Kristen Chadwick
kschadwick@partners.org
617-643-3907
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Frozen Bakery Additives Market (Preservative, Oxidizing Agent, Reducing Agent, Enzyme, Emulsifier) Worth $1.46 Million by 2018 - New Report by MarketsandMarkets
2. Demas Law Group Files Claim Against Townsend and Costco in Frozen Berries Case
3. FrozenPeaz Sponsors Salt Lake International Speedskating Team and Lana Gehring inTheir Quest for Olympic Gold
4. Frozen Food Production in China Industry Research Report – Now Available from IBISWorld
5. FrozenPeaz Launches Pre-habilitation Marathon Training Recovery Promotion
6. Frozenshoulder.com, New Research Shows Increase in Shoulder Injuries Due to Airline Baggage Regulations
7. New Zinga Frozen Yogurt Opens in Falls Church
8. 49 Now Sickened in Hepatitis A Outbreak Tied to Frozen Berry Mix
9. Frozen Food Production in the US Industry Market Research Report from IBISWorld has Been Updated
10. Zinga! Frozen Yogurt Touts Harvard Study for National Nutrition Month
11. Puppy Born From Frozen Embryo May Offer Hope to Endangered Wildlife
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... VA (PRWEB) August 28, 2014 ... development, today announced that it has partnered with ... with the performance start date of 2/4/2014 with ... of Homeland Security (DHS) agency that oversees lawful ... contract, Coveros and InfoZen will automate the integration ...
(Date:8/28/2014)... 2014 On September 1st, the National ... campaign. The goal is to help families and ... and effectively and without exposures to risky pesticides. ... “Children’s exposures to pesticides should be limited as ... Head lice are often trivialized in the media, which ...
(Date:8/27/2014)... Asheville, NC (PRWEB) August 28, 2014 ... for companies to acquire as part of a ... business. Aeroflow is positioned for taking ownership of ... foundation to increase economies of scale. , Last ... an agreement with Hometown Respiratory to increase service ...
(Date:8/27/2014)... The report provides market analysis of ... Range Finder, LIDAR, 3D scanner, Laser Weapon, Dazzlers, Laser ... Laser Altimeter) by Domain (Aerospace, Defense and Homeland Security) ... by MarketsandMarkets, and its application in the aerospace and ... Laser Systems market is expected to register a CAGR ...
(Date:8/27/2014)... an innovative company that provides many kinds of top quality ... are now offered on its website. In addition, the firm ... that place an order for its newly released items can ... , The company’s senior spokesman was excited to talk ... and old customers can buy cheap bamboo panels on our ...
Breaking Medicine News(10 mins):Health News:Coveros Partners with InfoZen on USCIS Transformation Integration Award 2Health News:Head Lice Can Be a Public Health Opportunity 2Health News:Head Lice Can Be a Public Health Opportunity 3Health News:Head Lice Can Be a Public Health Opportunity 4Health News:Aeroflow Healthcare Seeks Strategic Acquisition Opportunities 2Health News:Military Laser Systems Market Worth $2.73 Billion by 2020 - New Report by MarketsandMarkets 2Health News:Military Laser Systems Market Worth $2.73 Billion by 2020 - New Report by MarketsandMarkets 3Health News:Military Laser Systems Market Worth $2.73 Billion by 2020 - New Report by MarketsandMarkets 4Health News:BambooIndustry.com: Cheap Bamboo Panels for Clients Worldwide Offered Online 2
... its kind, have computed the rate of injury among competitive ... collegiate soccer or basketball// players. Led by researchers at Rhode ... study are published in the January 2007 issue of the ... competitive surfing has a relatively low risk of injury – ...
... the present guidelines should be modified affirms a recent ... Critical Care Medicine. This will need all foreign immigrants ... come from high risk areas around the world.This paper ... ,Data on all 2004 TB cases listed in the ...
... merely a figment of imagination. The feelings associated with it, ... be prevented or tackled// at the very onset, preventing it ... recent study shows that approximately 90 per cent of children ... miserable and homesick. This happens more often when children leave ...
... the winter cold and flu season//, a vocal health expert ... for preventing and treating the inflammation of the voice box. ... common cold and upper respiratory infection is something that is ... at some point in their life,” says Norman D. Hogikyan, ...
... are set to drastically lower the cost of medicines //and ... ,Sunil Shaunak, professor of infectious diseases at Imperial College, ... are leading clinical trials in India for a drug for ... way to invent new medicines and get them to market ...
... with normal lung function who later develop chronic cough ... chronic obstructive pulmonary disease (COPD). ,The results of ... for January 2007 of the American Journal of Respiratory ... Society. ,Isa Cerveri, M.D., of the Division ...
Cached Medicine News:Health News:Surfing Safer Than Soccer: Study 2Health News:Surfing Safer Than Soccer: Study 3Health News:TB can Be Eradicated in the U.S With Modified Guidelines: Study 2Health News:Coping With Homesickness 2Health News:Tips to Prevent and Treat Winter Laryngitis 2Health News:NRI Doctor's R&D Model in India to Slash Cost of Drugs 2Health News:Cough and Phlegm Cause Fourfold Increase in COPD Incidence 2
(Date:8/27/2014)... , Aug. 27, 2014 Sihuan Pharmaceutical ... the "Company"), a leading pharmaceutical company with the ... China,s prescription drug market, today ... and its subsidiaries (collectively the "Group") for the ... Financial HighlightsFor the Six months ended ...
(Date:8/27/2014)...  CVS Caremark (NYSE: CVS ) announced ... with MedStar Health, a leading health care system with ... the Washington, DC , region, which ... for patients. Through this clinical affiliation, MedStar Health patients ... counseling, chronic disease monitoring and wellness programs at CVS/pharmacy ...
(Date:8/27/2014)... , Aug. 27, 2014  UBM Medica US ... leading online community for medical imaging professionals, presents special ... for Medical Imaging Management,s 2014 Annual Meeting . ... coverage: , 11 Principles of Successful ... lead to greater profitability. , Why Don,t ...
Breaking Medicine Technology:Sihuan Pharmaceutical Announces 2014 Interim Results 2Sihuan Pharmaceutical Announces 2014 Interim Results 3Sihuan Pharmaceutical Announces 2014 Interim Results 4Sihuan Pharmaceutical Announces 2014 Interim Results 5Sihuan Pharmaceutical Announces 2014 Interim Results 6Sihuan Pharmaceutical Announces 2014 Interim Results 7CVS Caremark Announces New Clinical Affiliation with MedStar Health 2CVS Caremark Announces New Clinical Affiliation with MedStar Health 3Diagnostic Imaging Covers Association for Medical Imaging Management (AHRA) 2014 Meeting 2Diagnostic Imaging Covers Association for Medical Imaging Management (AHRA) 2014 Meeting 3
... Nov. 11 Shire plc ... biopharmaceutical company, today announced the re-launch of FOCUS ( ... patient support program for adults taking once-daily Vyvanse ... treatment of Attention-Deficit/Hyperactivity Disorder (ADHD), and the only online, branded ...
... Deloitte Recap LLC (Recap) has launched "Development ... Series by Deloitte. The series of biopharmaceutical business ... service tailored toward business development, corporate strategy, financial, ... , "Development Optimizer" provides flexible analytical tools for ...
Cached Medicine Technology:Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII 2Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII 3Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII 4Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII 5Deloitte Recap Launches New Solution for Clinical Development 2Deloitte Recap Launches New Solution for Clinical Development 3
... Focus multichannel pipettes speed ... reagents into microplates, with ... l volumes. The improved ... Focus multichannels, combined with ...
... in a wide variety of applications. • Whole ... can be freely rotated against the handle to ... an optimum angle towards the microtiter plate. • ... of most common pipette tips, and provides a ...
Pipetman 8X200 Multichannel Pipette is an eight-channel, fully adjustable, air-displacement pipette having a useful volume range from 20 L to 200 L. Robustwith the usual Gilson qualities this pipette...
... 96-well plates in mind, Pipetman Ultra ... biology applications: PCR* sequencing, immunology assays, ... Used with Diamond Tips from Gilson's ... will maximize performance and assure productivity.,* ...
Medicine Products: