Navigation Links
Use of certain lipid measures not more effective in predicting coronary heart disease
Date:8/14/2007

The lipid measure apolipoprotein (apo) B: apo A-I ratio is not a better predictor of coronary heart disease risk than traditional lipid ratios that include total cholesterol and HDL-C, according to a study in the August 15 issue of JAMA.

Current risk-prediction instruments and guidelines for coronary heart disease (CHD) prevention emphasize the use of low-density lipoprotein cholesterol (LDL-C), total cholesterol, or both for CHD risk assessment. But in recent years, some evidence has suggested that higher apo B (the primary protein component of LDL) and lower apo A-I (the primary protein component of high-density lipoprotein [HDL]) levels play a role in the development of CHD, and that these measures might be superior to traditional lipid measures for CHD risk prediction, according to background information in the article.

Erik Ingelsson, M.D., Ph.D., of the Framingham Study, Boston University School of Medicine, Framingham, Mass., and colleagues evaluated whether apolipoproteins (the protein component of serum lipoproteins) could be used instead of traditional lipid measures for CHD risk prediction in a large group of men and women who were part of the Framingham Offspring Study. The researchers evaluated serum total cholesterol, HDL cholesterol (HDL-C), LDL-C, nonHDL-C, apo A-I and apo B, and three lipid ratios (total cholesterol:HDL-C, LDL-C:HDL-C, and apo B:apo A-I) in 3,322 middle-aged white participants who were examined between 1987-1991 and were without cardiovascular disease. Fifty-three percent of the participants were women. After a median (midpoint) follow-up of 15.0 years, 291 participants, 198 of whom were men, developed CHD.

Our principal findings are 3-fold. First, even though the apo B:apo A-I ratio performed well overall in terms of CHD risk prediction and model performance measures in both sexes, the differences compared with other lipid variables were small and statistically nonsignificant. Non-HDL-C performed r
'/>"/>

Contact: Esta Shindler
508-935-3434
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New point scale to ascertain the stroke recovery
2. Certain Food Beneficial for the Heart
3. Sunlight Could Be Beneficial For Certain Types Of Cancer
4. Almonds As Effective As Certain Drugs In Lowering Cholesterol
5. Malarial gene ascertained
6. Calcium Supplements May Not Be Useful After A Certain Threshold Is Achieved
7. Indians are certainly having their greens and eating them too!
8. Cholesterol provides immunity against infection by certain parasites
9. Small Doses Of Radiation Can Help Certain Lung Cancer Patients
10. Culling followed by checking: Government to audit the documents, to ascertain no skeletons in the closet!
11. Effects Of Certain Food Related To Single Pain Receptors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... In the past few weeks, TheBeautyPlace.com has been undergoing ... to run maintenance on our shipping facilities to update ... PR Director. "It disrupted our regular shipping schedule but ... on track after having completed the maintenance." , Now, ... which has not allowed some calls to come in ...
(Date:4/18/2015)... April 18, 2015 “ ArcAngel ” was ... takes a look at the latest and coolest ... Troohey, the host of AppWatch and technology expert, conducted the ... personal safety app. , In a turbulent world, people ... Calling 911 should always be their first move, but some ...
(Date:4/17/2015)... 17, 2015 John Evans, a Gardant ... the Patio from 2 p.m. to 3 p.m. on ... 1320 Executive Ct. in Pekin, Illinois, serves older adults ... some help to maintain their independence. , Becky Baker ... treats will be served during the luau. , For ...
(Date:4/17/2015)... Oklahoma (PRWEB) April 17, 2015 Alcohol ... Drug Dependence (NCADD) notes that drinking and driving has ... At the same time, the link between alcohol ... as domestic abuse and violence and sexual assault, and ... According to the NCADD, 5.3 million adults in America ...
(Date:4/17/2015)... In Defense of Christians (IDC) Executive ... Wednesday April 15th, the European Parliament joined its voice ... the Armenian Genocide, “paying tribute, on the eve of ... innocent Armenian victims who perished in the Ottoman Empire.” ... for this timely and needed recognition of a tragic ...
Breaking Medicine News(10 mins):Health News:TheBeautyPlace.com Temporary Number Available 2Health News:A Personal Safety Application was Featured on NewsWatch Television 2Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 3Health News:In Defense of Christians Condemns Armenian Genocide 2Health News:In Defense of Christians Condemns Armenian Genocide 3
... taken ill Wednesday after inhaling methane gas leaking from a colliery ... leak was reported early morning from the Bathdih colliery of Bharat ... ,The 10 people of Barari Basti area who fell ... to be in critical condition. ,BCCL officials have rushed ...
... the ghastly video.,A slender girl dragged along by her headlocks, on ... a torrent, then her head is smashed with a concrete ... then victorious shouts are heard. ,In the eyes ... Duaa Khalil Aswad, 17, was to love a boy from another ...
... Administration (FDA) has approved the first birth control pill ... monthly preparation of pregnancy. ,Lybrel, produced ... a low dosage of hormones ethinyl estradiol and levonorgestrel, ... pill prevents conception by halting menstrual period indefinitely. ...
... at the Albert Einstein College of Medicine in Yeshiva ... ability to use radioactivity as an energy source ... ,According to Dr. Arturo Casadevall, chair of microbiology and ... this finding could trigger a recalculation of the Earth's ...
... Sipping tea is far better than drinking water, researchers said. ... three or more cups of tea can reduce the risk ... Carrie Ruxton from King's College London, it is a wrong ... better than water as it contains antioxidants. It does not ...
... of the state-run super speciality SSKM Hospital in Kolkata was ... during a medical test Tuesday night. ,"We ... charges of outraging the modesty of this 32-year-old lady during ... told IANS. ,"A complaint was lodged by the ...
Cached Medicine News:Health News:Women in Iraq More Unsafe Than Ever 2Health News:Astronauts can Now Feed on 'radiation-eating' Fungi 2
(Date:4/17/2015)... , April 17, 2015 TWi Pharmaceuticals, Inc. ... TWi Pharmaceuticals USA , has obtained ... United States.  It has been in close contact with ... expects to have its own label specialty generic products ... the U.S. pharma market. According to IMS ...
(Date:4/16/2015)... , April 16, 2015 A drug commonly taken ... of people with multiple sclerosis (MS), according to a study ... of Neurology,s 67th Annual Meeting in Washington, DC ... "About half of people with MS experience at some point ... which the nerve carrying vision from the eye to the ...
(Date:4/16/2015)... , April 16, 2015  Amgen (NASDAQ: AMGN ... quarter financial results on Tuesday, April 21, 2015, after ... will be followed by a conference call with the ... call from Amgen will be Robert A. Bradway ... of Amgen,s senior management team. Live audio ...
Breaking Medicine Technology:Epilepsy Drug May Preserve Eyesight for People with MS 2Amgen Announces Webcast Of 2015 First Quarter Financial Results 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: