Navigation Links
Use of amniotic membrane may cause complications in strabismus surgery
Date:1/3/2011

Philadelphia, PA, January 3, 2011 Postoperative adhesions are a major complication in strabismus surgery. Amniotic membrane has been used in the hopes of preventing these adhesions by forming a biological barrier during healing. In an article in the December 2010 issue of the Journal of AAPOS, the Official Publication of the American Association of Pediatric Ophthalmology and Strabismus, a team of researchers from Cairo University have discovered that the new approach may also have the opposite effect.

Dr. Rehab Kassem and coauthors describe how they wrapped the extraocular muscles with lyophilized amniotic membrane in a patient undergoing a strabismus reoperation on both medial rectus muscles. However, the surgical result was not optimal, and the patient underwent a fourth procedure that included exploration of the medial rectus muscles. Instead of finding less scarring, the surgeons found extensive adhesions and inelastic, fibrotic muscles.

Amniotic membrane may be fresh or preserved. Preserved amniotic membrane may be either frozen, air-dried, or freeze-dried. Frozen amniotic membrane is expensive and it must be stored at -80C, thus limiting its availability. Dried amniotic membrane is less expensive and does not require special storage conditions.

The authors of the article speculate that their results may have been due to the use of dried, rather than frozen, amniotic membrane. Writing in the article, Rehab Kassem, MD, states, "What caused the fibrosis in our case? Was it related to the use of amniotic membrane or was it coincidental, perhaps the result of excessive dissection to achieve a large recession? If the former, then was the fibrosis related to the nature (lyophilized vs. cryopreserved) of the amniotic membrane used or to its possibly having been placed toward the sclera rather than the muscle? In conclusion, although the cause of the fibrosis in our case is not clear, lyophilized amniotic membrane was ineffective in protecting against its development."

"There are only a few reports of the use of amniotic membrane in extraocular muscle surgery, and the results of those studies are equivocal," says David G. Hunter, MD, PhD, Editor-in-Chief of the Journal of AAPOS. "While this material may have been used successfully in other parts of the eye, strabismus surgeons should only consider using it around extraocular muscles in cases where there is already extreme scarring, and not as a preventive measure, as was done here."


'/>"/>

Contact: Rachael Zaleski
rachael.zaleski@elsevier.com
215-239-3658
Elsevier Health Sciences
Source:Eurekalert

Related medicine news :

1. Biocell Center Corporation Partners with New Englands Largest Community-Based Hospital Network to Offer a Unique Service in Amniotic Fluid Stem Cell Preservation
2. Amniotic fluid cells more efficiently reprogrammed to pluripotency than adult cells
3. Amniotic membrane used to repair human articular cartilage
4. Obstructive Sleep Apnea in Kids May Have Genetic Cause
5. UCLA study reveals how genes interact with their environment to cause disease
6. Virus Unlikely to Cause Chronic Fatigue Syndrome
7. RSA Innovator NetClarity Solves Networking Problems Caused by HP and Cisco Divorce
8. Popular nanoparticle causes toxicity in fish, study shows
9. Genetic cause discovered for rare bleeding disorder
10. Contact Dermatitis Can Be Irritating, Especially When the Cause is a Mystery
11. Acupuncture may relieve joint pain caused by some breast cancer treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever ... Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation ... as home to some of the world’s leading providers of cereal and other breakfast ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic ... many turn to unhealthy avenues, such as drug or alcohol abuse, as a coping ... released tools for healthy coping following a traumatic event. , Trauma sufferers tend to ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... ... is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
(Date:6/24/2016)... Research and Markets has ... 2015-2025: Applications, Technologies, Forecasts" report to their ... Electronics, Smart Skin, Structural Health Monitoring, Composite Smart ... electronics involves electronic and/or electrical components and circuits ... structures such as vehicle bodies or conformally placed ...
Breaking Medicine Technology: