Navigation Links
Use of Avastin and Erbitux in the Adjuvant Setting and Launches of Emerging Agents Will Drive the Colorectal Cancer Drug Market to $7.8 Billion in 2017

Unmet Need for Efficacious Therapies for Treating Patients With Mutated KRAS Genes Presents Significant Opportunity for Drug Developers, According to a New Report from Decision Resources

WALTHAM, Mass., March 11 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the launches of Roche/Genentech/Chugai's Avastin and Bristol-Myers Squibb/ImClone Systems*/Merck KGaA's Erbitux will drive the colorectal cancer market to grow by $900 million to $7.8 billion in 2017.

The new Pharmacor report entitled Colorectal Cancer finds that market growth will be driven by the launches of Avastin and Erbitux into the adjuvant setting in 2011 in the United States and 2012 in Europe. Additionally, among the emerging therapies that will launch for colorectal cancer over the next several years, AstraZeneca's Recentin, Pfizer's Sutent and Sanofi-Aventis/Regeneron's VEGF Trap will account for 9.2 percent of market sales in 2017 in the United States, France, Germany, Italy, Spain, the United Kingdom and Japan.

Although monoclonal antibodies such as Avastin and Erbitux and emerging tyrosine kinase inhibitors and vascular endothelial growth factor inhibitors will drive growth, generic erosion will take market share away from some currently-available therapies, including oxaliplatin (Sanofi-Aventis's Eloxatin/Eloxatine and Yakult Honsha's Elplat). The expected entrance of generic oxaliplatin in the U.S. colorectal cancer market in late 2009 and in Japan in 2013 will reduce major-market sales of branded forms of this agent by almost $800 million in 2017.

The report also finds that there is significant remaining unmet need in the market for treating patients with mutated KRAS genes who do not respond to therapy using epidermal growth factor receptor (EGFR) inhibitors.

"In recent years, clinical data have shown that patients with mutated KRAS genes do not respond to treatment with EGFR inhibitors, creating a significant unmet need for efficacious agents in the second-line setting for patients who have progressed on Avastin," said Decision Resources Analyst Marcus Hoyle. "This unmet need, coupled with a rising incidence of colorectal cancer, presents a considerable commercial opportunity for drug developers in this market."

*ImClone Systems is a wholly-owned subsidiary of Eli Lilly and Company.

About Decision Resources

Decision Resources ( is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.

About Decision Resources, Inc.

Decision Resources, Inc. is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely on this analysis and data to make informed decisions. Please visit Decision Resources, Inc. at

All company, brand, or product names contained in this document may be trademarks or registered trademarks of their respective holders.

    For more information, contact:

    Decision Resources                Decision Resources, Inc.
    Christopher Comfort               Elizabeth Marshall
    781-296-2597                      781-296-2563 

SOURCE Decision Resources
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Surveyed Oncologists Indicate that Avastin has Advantages over Temodar/Temodal in Increasing Overall Survival of High-Grade Glioma
2. Avastin and Other Emerging Agents Will Drive the Glioma Drug Market to More Than $1.8 Billion in 2017
3. Genentech/Roche/Chugais Avastin Will Garner More Than 20 Percent of the Total Breast Cancer Drug Market in 2017
4. Avastin Added to Chemo Helps Women With Advanced Breast Cancer
5. Avastin Added to Chemo Helps Women With Advanced Cancer
6. Off-Label Avastin Use for Wet Macular Degeneration
7. FDA OKs Avastin for Advanced Breast Cancer
8. In Combination With FOLFOX4, the Effect of Erbitux and Avastin On Survival Rates Will Drive Prescription Decisions in the Treatment of Stage III Colon Cancer
9. Despite Oncologists Willingness to Prescribe Avastin for Treatment of Breast Cancer, the FDA is Likely to Rule Against the Product on February 23
10. Many More Patients Can Now Benefit from Avastins Proven Survival Benefits
11. Taxol with avastin produces noteworthy results
Post Your Comments:
(Date:11/24/2015)... ... 2015 , ... The hospitals and health systems on this ... care. They have received recognition for excellence from various reputable organizations in areas ... Hospital Review selected hospitals for inclusion based on national rankings and awards from ...
(Date:11/24/2015)... ... 2015 , ... In response to recent news highlighting Oxycodone fraud, Novus Medical ... the United States grew 400 percent between 1999 and 2010, far more than the ... percent of all fatal drug overdoses. (1) , While oxycodone and the extended release ...
(Date:11/24/2015)... ... ... Serenity Point Rehabilitation, a holistic treatment center for substance abuse located in Marne, ... members at their recovery center. The videos highlight some of the various aspects of ... that make their recovery program so unique. , “Making the decision to seek treatment ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... Cleveland University-Kansas City (CU-KC), in Overland Park, Kansas. Benson, a fifth-trimester ... University President Carl S. Cleveland III on October 16. , “Katie is very ...
(Date:11/24/2015)... ... 24, 2015 , ... Autism Speaks, the world’s leading autism science and advocacy ... and the generosity of people around the world. On December 1, supporters can make ... – and share the personal stories behind those gifts. , Just as Black ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... 2015  In the pharmaceutical industry, companies want to ... quickly uncover new insights, tactics and strategies that will ... --> However, organizations often find it is ... ensure that all rules and regulations are met to ... barrier to efficiently launching market research projects is the ...
(Date:11/24/2015)... , 24. November 2015 Avery ... Pacemaker Systems, ist erfreut, die Berufung von ... bekannt geben zu können. ... --> Foto - ... (Schweden). Von 1984-1986 war er Fellow des ...
(Date:11/24/2015)... Sectra (STO: SECT B) announces ... a multi-year agreement to deploy Breast Imaging PACS ... provide the Breast Center a future-proof platform capable of expanding ... B) announces that Breast Center of Acadiana has ... Imaging PACS in its two freestanding imaging centers. This investment ...
Breaking Medicine Technology: