Navigation Links
Use Anemia Drugs for Cancer Patients With Caution, Experts Say
Date:10/26/2010

TUESDAY, Oct. 26 (HealthDay News) -- Physicians need to use caution when giving a class of drugs called erythropoiesis-stimulating agents (ESAs) to cancer patients who have anemia caused by chemotherapy, according to new medical guidelines.

And with rare exceptions, ESAs should not be given to cancer patients who are not receiving chemotherapy, according to joint guidelines issued by the American Society of Hematology and the American Society of Clinical Oncology.

ESAs (marketed as Procrit, Epogen and Aranesp) stimulate the bone marrow to produce more red blood cells but are associated with shorter survival and increased risk of blood clots and tumor progression, the guidelines noted.

However, ESAs reduce the need for red blood cell transfusions, which carry a risk of serious infection and adverse reactions in the immune system.

The guidelines offer specific recommendations on the use of ESAs. Among them:

  • ESAs should not be given to cancer patients who are not receiving chemotherapy, except for those with myelodysplastic syndrome (MDS).
  • Doctors should discuss individual risks and benefits of ESAs and blood transfusion with patients before therapy. This shared decision-making is critical.

"This updated guideline offers clinicians the latest synthesis of the medical evidence surrounding the use of ESAs in patients with cancer, including appropriate cautions where evidence is lacking or where risks may outweigh the use of ESAs," guideline panel co-chair Dr. J. Douglas Rizzo, professor of medicine at the Medical College of Wisconsin, said in an American Society of Hematology news release.

"These guidelines touch on almost all aspects of the use of ESAs in patients with cancer and MDS, as well as secondary issues, such as the role of iron supplementation," Dr. Samuel Silver, a member of the ASH Committee on Practice and a professor of internal medicine at the University of Michigan, added in the news release.

The updated guidelines appear online Oct. 25 ahead of print in the Nov. 18 issue of Blood and the Nov. 20 issue of the Journal of Clinical Oncology.

More information

The U.S. Food and Drug Administration has more about ESAs.

-- Robert Preidt

SOURCE: American Society of Hematology, news release, Oct. 25, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. FDA Advisers Back Anemia Drugs for Kidney Patients
2. Anemia Drugs Could Pose Threat to Some Kidney Patients
3. Stroke prevention study in children with sickle cell anemia, iron overload stopped early
4. OHSU joins forces with UO, Harvard to accelerate Fanconi anemia research
5. Anemia Drugs Hold Dangers for Kidney Patients
6. Anemia Harder to Treat in Black Children With Kidney Disease
7. Anemia tougher to tackle in black children with kidney disease
8. For Some on Dialysis, Anemia Drugs Pose Risks
9. FDA Tightens Controls on Anemia Drugs
10. FDA Calls for New Warnings on Some Prostate Cancer Drugs
11. Penn study gives hope for new class of Alzheimers disease drugs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Use Anemia Drugs for Cancer Patients With Caution, Experts Say 
(Date:1/17/2017)... ... January 17, 2017 , ... Peoples Health is ... Health network on Dec. 1, 2016. Peoples Health, a Metairie-based Medicare Advantage company, ... an exciting addition to our provider network, and the addition will benefit our ...
(Date:1/17/2017)... ... January 17, 2017 , ... Wettstein Agencies, a Denver ... business professionals throughout central Colorado, is joining local nonprofit Aurora Warms The Night ... The Night organization is committed to breaking the cycle of homelessness and poverty ...
(Date:1/17/2017)... Tyler, TX (PRWEB) , ... January 17, 2017 ... ... serving Texas families from two offices in Tyler, has announced the latest beneficiary ... Red Ribbon Wish Network, a nonprofit organization dedicated to fulfilling the dreams of ...
(Date:1/16/2017)... ... January 17, 2017 , ... ... an internationally recognized leader in the fast-casual category, announces a hearty and wholesome ... Good Egg Breakfast Sandwich, Turkey Mash-Up Sandwich, Cranberry Crunch & Honey Parfait, Slow ...
(Date:1/16/2017)... ... , ... With the Grand Opening Event planned for February 3, 2017, the ... and the general public. Built in five months by Centerpoint, the 60,000 square foot ... or pickleball courts. The space is also suitable for indoor soccer and football training. ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... Research and Markets has announced the addition of the ... their offering. ... The global fluoropolymer market in the healthcare industry to grow at ... Global Fluoropolymer Market in the Healthcare Industry 2016-2020, has been prepared ... The report covers the market landscape and its growth prospects over ...
(Date:1/17/2017)... , Jan. 17, 2017  In a letter to ... Jo Ann Jenkins outlines AARP,s priorities for Americans ... Security, ensuring access to affordable health care coverage, and ... the letter Jenkins writes to President-elect Trump that "Our ... are counting on you to protect their Medicare and ...
(Date:1/17/2017)... , Jan. 17, 2017  In a preview of ... Annual Congress, Astute Medical, Inc., developer of the NephroCheck ... the test, which identifies hospital patients at risk of developing ... take place this month at the Hawaii ... January 21 through January 25. AKI is one ...
Breaking Medicine Technology: