Navigation Links
Urine test best detects alcohol use in liver transplant candidates, recipients
Date:5/8/2014

Researchers from Italy confirm that urinary ethyl glucuronide (uEtG) accurately detects alcohol consumption in liver transplant candidates and recipients. The study published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, suggests that a combination of uEtG and the Alcohol Use Disorders Identification Test for alcohol consumption (AUDIT-c) are best in alerting doctors to alcohol consumption by patients undergoing evaluation for liver transplantation or who have received liver transplants.

Alcoholic liver disease is one of the most common reasons for liver transplantation in Europe and the U.S say experts. Furthermore, studies suggest that up to 49% of liver transplant recipients struggle with alcohol relapse, which may cause complications with the graft. In fact, medical evidence found that transplant recipients who relapse have a poorer survival rate than abstinent patients.

"Assessing alcohol consumption is crucial in the selection of liver transplant candidates," explains Dr. Paolo Angeli from the University of Padova in Italy. "Equally important is the ability to detect alcohol use in liver transplant recipients so early intervention for alcohol relapse can take place."

For the present study the research team evaluated the effectiveness of uEtg, AUDIT-c, serum ethanol (sETOH), urinary ethanol (uETOH), and carbohydrate-deficient transferrin (CDT) in assessing drinking status in 121 liver transplant candidates and recipients. Participants provided blood and urine samples at each visit to detect all alcohol markers.

Researchers detected alcohol consumption in 31% of participants, with uEtG found to be the strongest marker of alcohol use. Compared to CDT, uEtG was also more accurate in predicting the amount of alcohol consumption. When used together uEtG and AUDIT-c were more accurate in assessing alcohol consumption than CDT and AUDIT-c. In patients with a negative AUDIT-c, uEtG was the most effective indicator of drinking status.

The authors recommend that AUDIT-c and uEtG be routinely used in transplant candidates and recipients to monitor drinking status. Dr. Angeli concludes, "It's vital that patients abstain from damaging drinking behavior following liver transplant to avoid graft loss or even death. When used together, uEtG and AUDIT-c provide an important tool in the management of transplant patients at risk for alcohol relapse."


'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Related medicine news :

1. Electronic nose sniffs out prostate cancer using urine samples
2. InventHelp Inventor Develops Infant Urine Collection Device (OCM-592)
3. EZ-P Enables Female Users to Give Urine Samples More Conveniently - Designed by InventHelp Client (DLL-2593)
4. Protein-based urine test predicts kidney transplant outcomes
5. Stem cells in urine easy to isolate and have potential for numerous therapies
6. Urine biomarker test can diagnose as well as predict rejection of transplanted kidneys
7. ATAGO Urine Specific Gravity Refractometers Continue to Catch Drug Test Cheaters
8. RI Hospital: Nearly half of older women diagnosed with UTI not confirmed in urine culture
9. Microscopic blood in urine unreliable indicator of urinary tract cancer
10. InventHelp Client Patents “LessMess” – Invention Could Reduce Messes and Smells Caused by Splashed Urine
11. Purines fend off surgery-related damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... ... May 23, 2017 , ... London, May 23, 2017: Walter Schindler, the Founder ... as a Guest Speaker and Contributor to a weeklong series of classes, meetings, field ... , Walter Schindler and SAIL Capital have received an ...
(Date:5/23/2017)... ... May 23, 2017 , ... Diagnotes, an Indianapolis-based ... standard feature on its secure clinical communication platform. The platform allows clinicians to ... on the type and urgency of a situation. , “We know from ...
(Date:5/23/2017)... ... 2017 , ... Therachat , a smart guided journaling tool for improving ... current state of anxiety in support of National Mental Health Awareness Month. , The ... and benchmarked general anxiety levels as well as identified the top triggers, impact to ...
(Date:5/22/2017)... , ... May 22, 2017 , ... Today, Our Urgent ... MO with a public ribbon cutting ceremony. Since opening over a month ... alternative to the emergency room. The new Our Urgent Care walk-in clinic is ...
(Date:5/22/2017)... CA (PRWEB) , ... May 22, 2017 , ... ... will sponsor a program on Wellocity to empower WeightZone Factor members to track ... medications, and get an excellent health education, all on their mobile phones. It ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... Hologic, Inc. (Nasdaq: HOLX ) announced today ... ended April 1, 2017 .   GAAP diluted earnings ... the prior year period as the sale of the ... non-GAAP diluted EPS of $0.50 increased 6.4%.  Revenue of ... terms.  Excluding the effects of blood screening and the ...
(Date:5/10/2017)... , May 10, 2017  The Corporate ... or employees of sleep therapy clinics to call ... sleep therapy clinic is involved in a substantial ... interested in hearing from an employee of a ... in a kickback scheme to provide medical practice groups ...
(Date:5/10/2017)... Md. , May 10, 2017 CSSi, ... solutions for the clinical research industry, is proud to ... www.CSSiEnroll.com . The new website features both enriched content ... user experience and enhances the company,s already well-established position ... industry. "After many months of hard ...
Breaking Medicine Technology: