Navigation Links
Urine biomarker test can diagnose as well as predict rejection of transplanted kidneys
Date:7/3/2013

dical Center and NewYork-Presbyterian/Columbia University Medical Center. The successful results of that trial are detailed in the July 4 issue of NEJM.

Such a test is sorely needed to help improve the longevity of kidney transplants and the lives of patients who receive these organs, says study co-author Dr. Darshana Dadhania, associate professor of medicine and medicine in surgery at Weill Cornell Medical College and associate attending physician at NewYork-Presbyterian Hospital.

Dr. Dadhania says that the primary blood test now used to help identify rejection -- creatinine, which measures kidney function -- is much less specific than the three-gene signature.

"Creatinine can go up for many reasons, including simple dehydration in a patient, and when this happens we then need to do a highly invasive needle-stick biopsy to look at the kidney and determine the cause. Our goal is to provide the most effective care possible for our transplant patients, and that means individualizing their post transplant care," she says. "Using an innovative biomarker test like this will eliminate unnecessary biopsies and provide a yardstick to measure adequate immunosuppression to keep organs -- and our patients -- healthy."

Although a number of researchers have tried to develop blood or urine-based tests to measure genes or proteins that signify kidney organ rejection, Dr. Suthanthiran and his research team were the first to create a gene expression profile urine test -- an advance that was reported in NEJM in 2001 and, with an update also in NEJM, in 2005.

The research team measured the levels of messenger RNA (mRNA) molecules produced as genes are being expressed, or activated, to make proteins. To do this, they developed a number of sophisticated tools to measure this genetic material. "We were told we would never be able to isolate good quality mRNA from urine," he says. "Never say never."

He and his co
'/>"/>

Contact: Linda Kamateh
lib9027@nyp.org
212-821-0560
Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. ATAGO Urine Specific Gravity Refractometers Continue to Catch Drug Test Cheaters
2. RI Hospital: Nearly half of older women diagnosed with UTI not confirmed in urine culture
3. Microscopic blood in urine unreliable indicator of urinary tract cancer
4. InventHelp Client Patents “LessMess” – Invention Could Reduce Messes and Smells Caused by Splashed Urine
5. Purines fend off surgery-related damage
6. In Diabetes, Any Protein in Urine May Signal Heart Risk
7. Biomarker predicts risk of breast cancer recurrence after tamoxifen treatment
8. New concussion data: 2 biomarkers better than 1
9. MET protein levels show promise as biomarker for aggressive colon cancer
10. Researchers narrow the search for biomarkers of drug resistance in head and neck cancer patients
11. Kantar Health Launches CancerMPact Biomarker Analysis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2014)... 2014 Ticket Down is a ... This popular ticket exchange is offering their customer appreciation ... 2015 schedule of tours is beginning to fill up. Many ... plans to hit the road, including 21-year-old pop superstar, Ariana ... “Honeymoon Tour,” which will take her to 25 cities across ...
(Date:9/20/2014)... Lifeinsurancequoteterm.net has released a new blog post ... insurance plan provides for vulnerable family members. , ... a top priority for every provider. It is now ... examinations and visiting a doctor. , Life insurance ... coverage up to $300,000, but only to healthy applicants. ...
(Date:9/20/2014)... TX (PRWEB) September 20, 2014 ... Forecast and Market Analysis to 2023?. The asthma ... decade, as it has become saturated with relatively ... inhaled corticosteroids (ICSs), inhaled corticosteroids and long-acting beta-agonists ... facing increasing generic competition. However, the launch of ...
(Date:9/20/2014)... Traditionally dentists have advised their patients against drinking coffee and ... re-visiting that advice and changing his stance after considering two ... on oral health. “There’s good news and great news,” says ... in protecting against gum disease, and red wine can help ... from the September 2014 issue of Boston University School ...
(Date:9/20/2014)... Oshkosh, Wisconsin (PRWEB) September 20, 2014 ... for the young star’s tour performances. She will visit ... 25th of February until the 16th of April. , ... Ariana Grande Honeymoon Tour tickets at QueenBeeTickets.com. , The ... the opportunity to see their favorite young singer in ...
Breaking Medicine News(10 mins):Health News:Ariana Grande Tickets in Phoenix, Los Angeles, Anaheim, San Jose, Seattle, and Vancouver Go on Sale Today 2Health News:Ariana Grande Tickets in Phoenix, Los Angeles, Anaheim, San Jose, Seattle, and Vancouver Go on Sale Today 3Health News:No Medical Exam Life Insurance Provides Financial Protection for Families 2Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 2Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 3Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 4Health News:South Charlotte Dentist, Dr. James Wells, is Changing His Advice on Coffee and Wine Drinking 2Health News:South Charlotte Dentist, Dr. James Wells, is Changing His Advice on Coffee and Wine Drinking 3Health News:Discount Ariana Grande Tickets: QueenBeeTickets.com Delights Fans with Discount Concert Tickets for Ariana Grande’s 2015 Honeymoon Tour 2
... exciting opportunities in occupational therapy. , ... ... Health Schools announces the launch of their latest resource center ... and education, the new resource center can be found at ...
... Med Labs Research leads research for local patients , ... Houston, TX, February 10, 2009: ... on the things you enjoy and important tasks that you need to complete. ... talked about or learned a short time ago. Consider how you would ...
... CatalogST. LOUIS, Feb. 10 SAFC Supply Solutions(R), a ... Group (Nasdaq: SIAL ) , and ... that it has added 50 new Certified Organics products ... line. Details of the new products are available ...
... Inc., today filed a formal protest and requested a ... managed behavioral health care contract RFP 09-630-7903-0001, which was ... New Mexico believes a stay is in the best ... consumers who will be adversely affected by the potential ...
... Freedom (IHF) is warning the public that the economic ... each American to use "an" electronic health record (EHR) ... to add opt-out and patient-consent provisions to ensure true ... line is that if YOU want to control the ...
... Full Value,Committee announced today that it has filed ... materials and is commencing,distribution of those soliciting materials ... ) ("LCAV") to solicit consents to replace the ... highly qualified nominees. The Full,Value Committee,s director ...
Cached Medicine News:Health News:New Occupational Therapy School and Career Resource on All Allied Health Schools 2Health News:New Occupational Therapy School and Career Resource on All Allied Health Schools 3Health News:New Research Study in Houston, Texas Seeks Improved Quality of Life for People in the Future with Schizophrenia 2Health News:SAFC Supply Solutions Introduces Certified Organics to Flavors & Fragrances Product Line 2Health News:SAFC Supply Solutions Introduces Certified Organics to Flavors & Fragrances Product Line 3Health News:SAFC Supply Solutions Introduces Certified Organics to Flavors & Fragrances Product Line 4Health News:ValueOptions(R) New Mexico Files Formal Protest of Award of New Mexico Behavioral Health Contract to United 2Health News:ValueOptions(R) New Mexico Files Formal Protest of Award of New Mexico Behavioral Health Contract to United 3Health News:ValueOptions(R) New Mexico Files Formal Protest of Award of New Mexico Behavioral Health Contract to United 4Health News:Economic Stimulus Bill Mandates Electronic Health Records for Every American by 2014 - With No Opt-out Provision 2Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 2Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 3Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 4Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 5Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 6Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 7Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 8Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 9Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 10Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 11Health News:The LCA-Vision Full Value Committee Commences Consent Solicitation to Elect New Board of Directors at LCA-Vision (Nasdaq: LCAV) and Sends Letter to Stockholders 12
(Date:9/19/2014)... , Sept. 19, 2014  4WEB Medical announces the ... foot and ankle osteotomy implants on the market ... Society annual meeting in Chicago . ... of a surgeon,s osteotomy needs with 74 size options included ... had smaller offerings of only 15 to 18 implant sizes, ...
(Date:9/19/2014)... 19, 2014 The American Association for Homecare ... and Manufacturing has joined the AAHomecare Corporate Partner Program. ... Diamond have been actively involved in AAHomecare for ... has quickly grown into a major global manufacturer of ... allows AAHomecare to increase efforts on behalf of the ...
(Date:9/19/2014)... , Sept. 19, 2014 Five MinuteClinic walk-in medical ... Memphis metropolitan area. Three clinics opened in ... month. A fourth clinic will be added in Springfield ... Bartlett is expected to open October 22.  MinuteClinic ... in the United States . The ...
Breaking Medicine Technology:4WEB Medical Unveils 3D-Printed Osteotomy Truss System 2Drive Medical Design & Manufacturing Joins AAHomecare Corporate Partner Program 2MinuteClinic Walk-in Medical Clinics Opening in Memphis 2MinuteClinic Walk-in Medical Clinics Opening in Memphis 3
... ... a new market research report is available in its ... , http://www.reportlinker.com/p0164367/Immunoassay-Instruments---Global-Market-Trends.html , Immunoassay and ... due to the innovation of new technologies and introduction ...
... , NEW ... market research report is available in its catalogue: , ... Perspective , http://www.reportlinker.com/p0164320/Electrodes-for-Medical-Devices---A-Global-Market-Perspective.html , Electrodes in ... nerve cells that are created by chemical reactions. Medical ...
Cached Medicine Technology:Reportlinker Adds Immunoassay Instruments - Global Market Trends 2Reportlinker Adds Immunoassay Instruments - Global Market Trends 3Reportlinker Adds Immunoassay Instruments - Global Market Trends 4Reportlinker Adds Immunoassay Instruments - Global Market Trends 5Reportlinker Adds Immunoassay Instruments - Global Market Trends 6Reportlinker Adds Immunoassay Instruments - Global Market Trends 7Reportlinker Adds Electrodes for Medical Devices - A Global Market Perspective 2Reportlinker Adds Electrodes for Medical Devices - A Global Market Perspective 3Reportlinker Adds Electrodes for Medical Devices - A Global Market Perspective 4Reportlinker Adds Electrodes for Medical Devices - A Global Market Perspective 5Reportlinker Adds Electrodes for Medical Devices - A Global Market Perspective 6Reportlinker Adds Electrodes for Medical Devices - A Global Market Perspective 7
CEMEX Fast Set is a solution for multiple indications and preferences. It is a self-contained delivery system in a convenient 70gm size....
... Techno-Aide provides the highest level ... highest quality lead protective eyewear. ... + tolerance allowed. Mfg supervised by ... All lens meet or exceed standards ...
This flexiable metal clip-on easily attaches to most frames and allows for excellent radiation protection. Not available with side shields or in prescription....
All New Ultra Pb Series Glasses...
Medicine Products: