Navigation Links
Urine Test Could Gauge Smokers' Lung Cancer Risk
Date:4/19/2009

Those with higher levels of a compound had nearly 9 times the risk, scientists say

SUNDAY, April 19 (HealthDay News) -- Someday, a simple urine test might spot smokers at highest risk for lung cancer, scientists report.

The research is still in its preliminary stages, and it may be years before such a test becomes publicly available. But if it works, the urine-based screen could give added motivation to smokers who can't find other reasons to quit, said study author Dr. Jian-Min Yuan, an associate professor at the University of Minnesota.

"You can focus on the higher-risk people, maybe have them come into smoking-cessation programs," Yuan said. "Hopefully, it can reduce the amount of tobacco that is consumed."

The findings were to be released Sunday at the American Association for Cancer Research's annual meeting in Denver.

The U.S. Centers for Disease Control and Prevention estimates that about 23 percent of adult Americans are smokers, and smokers account for about 87 percent of cases of lung cancer, the number one cancer killer.

Currently, there is no way to determine which smokers are most likely to develop lung cancer. Doctors do know that smokers with chronic obstructive pulmonary disease or a prior family history of lung cancer are at higher risk, said Dr. Norman Edelman, chief medical officer with the American Lung Association.

In the new study, researchers in Minnesota, Singapore and China examined findings from two prior surveys.

One study looked at more than 18,000 men who enrolled when they were aged 45-64 in Shanghai, China. The other study included more than 63,000 men and women of Chinese descent, aged 45-74, and was conducted in Singapore between 1993 and 1999.

In the new study, the researchers focused on 246 smokers who developed lung cancer and 245 smokers who were similar to them. The researchers examined urine samples from the subjects and tried to figure out if a biologic marker known as NNAL could predict cases of lung cancer.

The team found that the third of smokers who had the highest levels of NNAL and a marker called cotinine were 8.5 times more likely to develop lung cancer than those with levels in the lowest third and similar histories of smoking.

"We compared apples with apples -- people who smoked the same amount of cigarettes and for the same amount of years," Yuan noted.

Scientists could perfect the predictive powers of the test, which costs about $100 to $120, within a few years, Yuan said.

But there's a catch: Currently, no intervention -- outside of quitting smoking -- reduces a smoker's chance of developing lung cancer.

A screening test could help doctors figure out which smokers should undergo more sophisticated screening, Edelman said, but at the moment it's difficult to detect tumors in their early stages.

"We need better and more sophisticated strategies to allow us to screen for early lung cancer, as that is only when it is curable but also when there are no symptoms," he said.

More information

There's more on the smoking-cancer connection at the American Cancer Society.



SOURCES: Jian-Min Yuan, M.D., Ph.D., associate professor, University of Minnesota, Minneapolis; Norman H. Edelman, M.D., chief medical officer, American Lung Association, Chicago; April 19, 2009, presentation, American Association for Cancer Research annual meeting, Denver


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Urine Test May ID Unhealthy Diets
2. Breath or urine analysis may detect cancer, diabetes
3. Taurine: Key to the visual toxicity of an anti-epileptic drug for children?
4. Urine Test May One Day Predict Prostate Cancer
5. Super Prostate Product - More Beta-sitosterol, all-natural Best Prostate(TM) Formula for Enlarged Prostate and BPH - Increases Urine Flow, Reduces Waking and Improves Quality of Life
6. Urine protein may be present before hypertension diagnosis in at-risk adolescents
7. Urine Test Results Can Point to Heart Dangers
8. Contamination from depleted uranium found in urine 20 years later
9. Human Urine Safe, Productive Fertilizer
10. K-State engineers create DNA sensors that could identify cancer using material only one atom thick
11. Colon cancer shuts down receptor that could shut it down
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Urine Test Could Gauge Smokers' Lung Cancer Risk
(Date:3/29/2017)... Md., and MINNETONKA, Minn. (PRWEB) , ... March ... ... the development of medical office buildings (MOBs) and other outpatient facilities, and who ... project to look exclusively at those questions, Revista and Healthcare Real Estate Insights ...
(Date:3/29/2017)... Norwalk, CT (PRWEB) , ... March 29, 2017 , ... ... Valuing —on Thursday, April 20, 2017, at 1:00 PM ET. A recording of the ... of the Interactive Webinar Series. , Home health and hospice companies are still popular ...
(Date:3/29/2017)... PITTSBURGH, PA (PRWEB) , ... ... ... the eastern suburbs and South Hills of Pittsburgh now have easier access ... western Pennsylvania only by Allegheny Health Network (AHN). Orthopaedic surgeons at Forbes ...
(Date:3/29/2017)... ... ... VisualSP has helped over 1.5 million SharePoint users learn the content management system ... Help System for SharePoint was at the farm level. Enterprises using SharePoint Online in ... The company recently released a modified version of the Help System, VisualSP for Site ...
(Date:3/28/2017)... ... March 28, 2017 , ... ... first technology to directly address the resolution to globally reduce the harmful use ... patented compound of FDA and TTB approved ingredients that when infused into alcohol, ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)...  Maxor National Pharmacy Services, LLC ("Maxor"), a leading ... Leah Bailey as General Counsel.  Bailey will serve ... With more than 13 years of experience ... on health care, Bailey joins the Maxor team coming ... advised the PBM, Specialty, and Mail Order business areas ...
(Date:3/29/2017)... , March 29, 2017  Designers of primary cell ... solution size by 50% and extend battery life with ... management integrated circuit (PMIC) from Maxim Integrated Products, Inc. ... a low input voltage of just 0.7V for new ... Silver Oxide, as well as the more common Alkaline ...
(Date:3/29/2017)... Michigan , USA, March 29, 2017 ... Company that Cares by People magazine, in partnership with ... of 50 companies on the list. This list highlights ... that have succeeded in business while also demonstrating respect, ... the environment.  To determine the companies ...
Breaking Medicine Technology: