Navigation Links
Uric acid may provide early clues to diabetic kidney disease
Date:3/18/2008

For patients with type 1 diabetes, increased levels of uric acid in the blood may be an early sign of diabetic kidney diseaseappearing before any significant change in urine albumin level, the standard screening test, reports a study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology.

The results raise the possibility that treatments to reduce uric acid might slow the decline of renal function in patients with diabetes. "Thus we have the hope of having a means to thwart the loss of kidney function while function is still in a relatively preserved stage," comments Dr. Elizabeth T. Rosolowsky of Joslin Diabetes Center, Boston.

The researchers measured serum uric acid concentration in 675 patients with type 1 diabetes. On screening tests, 311 patients had small amounts of the protein albumin in the urine. This resultcalled microalbuminuriais generally regarded as a harbinger of kidney function loss in diabetic kidney disease (nephropathy). The other 364 patients had normal urine albumin levels.

None of the patients had higher levels of albumin (albuminuria) representing more advanced diabetic nephropathy. Nevertheless, one in five had some impairment of kidney function on a standard test, the glomerular filtration rate. "Our research showed that loss of kidney function takes place even in the absence of albuminuria in patients with type 1 diabetes," says Dr. Rosolowsky.

In contrast, the serum uric acid level was consistently related to kidney functionthe higher the uric acid, the lower the kidney function. "The serum concentration of uric acid in these patients varied in a manner consistent with its having played a role in this early loss of kidney function," according to Dr. Rosolowsky.

Urine albumin is commonly measured to identify patients with type 1 diabetes at risk of developing nephropathy. "Historically, it was believed that the start of kidney function loss happened only wh
'/>"/>

Contact: Shari Leventhal
sleventhal@asn-online.org
202-416-0658
American Society of Nephrology
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Study provides hope that some transplant patients could live free of antirejection drugs
2. Study provides hope that some transplant patients could live free of anti-rejection drugs
3. Glades General Hospital First in Palm Beach County to Provide On-Site Electronic Birth Registration
4. Providence St. Joseph Medical Center, Caregivers Reach Agreement on a Union Contract
5. USAID Provides Additional Wildfire Assistance to Greece
6. MinuteClinic Becomes Participating Provider with Assurant Health
7. Over 500,000 Health Care Providers Now Cutting Costs, Saving Time Through CAQH Administrative Simplification Initiative
8. LifeMasters Provides Tips for Maintaining a Healthy Blood Cholesterol Level
9. New knock-out gene model provides molecular clues to breast cancer
10. Area Health Care Providers Announce Plans to Integrate Services
11. Crdentia Selected by High Rock Raceway to Provide Healthcare Staffing Services
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Uric acid may provide early clues to diabetic kidney disease
(Date:12/26/2014)... India Network Foundation, a non-profit US based sponsor ... a new version of “ EasySelect ”, a software ... for their visiting parents. The technology tool is designed ... when choosing an insurance plan by showing the benefits ... clicks. Many elderly Asian Indian parents often find it ...
(Date:12/26/2014)... 26, 2014 DW-InductionHeating.com (DaWei Induction Heating ... researching and developing, producing and marketing of a series ... business announces their new series of induction brazing ... the company, induction brazing refers to the ... filler material and heat. The manager says that there ...
(Date:12/25/2014)... 26, 2014 The microscopy market ... 7.2% to reach $5,756.0 million by 2019. Optical ... market. The electron microscopes product segment is expected ... period. , Rising focus on nanotechnology, technological advancements, ... the microscopy market. , Get Full Copy of ...
(Date:12/25/2014)... December 26, 2014 The ... combines beauty, strength and durability. Today, the business ... which is valid until Jan. 30, 2015. , ... of traditional hardwood. BambooFlooringChina.com is a well-known brand ... consumers worldwide to find a reliable bamboo flooring ...
(Date:12/25/2014)... The report “TS-1 (Colorectal Cancer) – Forecast and ... landscape, unmet needs, current pipeline and commercial opportunities in ... which is typically used for treating colorectal cancer. It ... gastric cancer and pancreatic cancer. TS-1 is composed of ... approved in 1999 in Japan for the treatment of ...
Breaking Medicine News(10 mins):Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 3Health News:Induction Brazing Equipment Series From DaWei Induction Heating Co., A Reliable Supplier Of Induction Heating Equipment 2Health News:Microscopy Market Hit to $5,756.0 Million by 2019 - New Research Report by MarketsandMarkets 2Health News:Microscopy Market Hit to $5,756.0 Million by 2019 - New Research Report by MarketsandMarkets 3Health News:Microscopy Market Hit to $5,756.0 Million by 2019 - New Research Report by MarketsandMarkets 4Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3
... 41, were well aware of the toll that morbid ... from high blood pressure, diabetes and thyroid disease and ... they scheduled their gastric bypass surgeries at Cedars-Sinai Medical ... joined a growing number of severely overweight Americans who ...
... been the cornerstones of managing type 2 diabetes. But ... ,Now, a new systematic review shows that exercise ... sensitivity to insulin, and decreases blood lipids (fats) while ... 2 diabetes is an increasing problem in Western societies ...
... anti-smoking group, has admitted to making use of an actor ... cancer//. ,The advertisement shows a heavily made-up woman displaying ... and nose, who warns that smoking caused her mouth cancer. ... she says. ,Todd Harper, Quit executive director, said ...
... rare form of viral fever, has taken the form of ... reportedly infected with its virus in eight states, an official ... magnitude. There is no case of Chikungunya reported from the ... Kerala in the southern India, other states like Tamil Nadu, ...
... potential drugs that interfere with the action of one ... problems led scientists// at Johns Hopkins to create a ... to see multiple, real-time chemical reactions in living cells. ... in the journal ACS Chemical Biology. ,Most ...
... Burgess Hill, West Sussex was prosecuted for intentionally infecting his ... to arrest him.// ,He failed to appear ... Court that the 47-year-old businessman would be sentence in his ... bodily harm to his lover. James has admitted infecting his ...
Cached Medicine News:Health News:Weight-Loss Surgeries Changing Lives 2Health News:Weight-Loss Surgeries Changing Lives 3Health News:Weight-Loss Surgeries Changing Lives 4Health News:Exercise in Itself Improves Blood Glucose Control in Type 2 Diabetes 2Health News:Exercise in Itself Improves Blood Glucose Control in Type 2 Diabetes 3Health News:New Tool to Watch Real-Time Chemical Activity in Cells 2Health News:New Tool to Watch Real-Time Chemical Activity in Cells 3
(Date:12/24/2014)... DIEGO , Dec. 23, 2014 ResMed (NYSE: ... significant patent infringement action against Chinese medical device manufacturer BMC ... (ITC) ruled today that BMC,s masks listed below infringe ResMed,s ... or selling these masks in the United States ... iVolve N2 nasal mask , Willow nasal pillows mask ...
(Date:12/24/2014)... ALEXANDRIA, Va. , Dec. 23, 2014 /PRNewswire-USNewswire/ ... stringent diastolic blood pressure target for people with ... either moderate or high doses of statins, in ... risk management enacted by the American College of ... recommendations are reflected in the most recent changes ...
(Date:12/22/2014)... , Dec. 22, 2014  CytoSorbents Corporation ... its CytoSorb® blood purification technology to help fight ... in 28 countries worldwide, today announced the appointment ... MD, FACS, as its Senior Vice President of ... Dr. Di Russo is an ...
Breaking Medicine Technology:ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 3New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5
... Depomed, Inc. (NASDAQ: DEPO ) today ... payment from Ironwood Pharmaceuticals, Inc. following the development and ... candidate meeting pre-specified attributes under its Research Collaboration and ... in July 2011. Under the terms of the agreement, Depomed ...
... China, May 11, 2012 /PRNewswire-Asia/ -- Simcere Pharmaceutical Group ... a leading pharmaceutical company specializing in the development, manufacturing, ... today announced that the annual general meeting of shareholders ... 2012 at 10 a.m. Beijing time. The meeting will ...
Cached Medicine Technology:Depomed Announces Receipt of $1 million Milestone Payment From Ironwood Pharmaceuticals, Inc. 2Simcere Pharmaceutical Group Provides Notice of Annual General Meeting 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: