Navigation Links
UofL researchers uncover mechanism in saliva production
Date:6/2/2011

Secretory Protein (PSP), selectively and directly binds to a rare lipid, a type of fat molecule called PtdIns(3,4)P2, present only in certain cell membranes - and only present on one side of the membrane. Darling also found PtdIns(3,4)P2 can flip to the inner part of the vesicle membrane giving PSP the opportunity to bind it.

"These data imply that phosphatidylinositol-phosphate lipids like PtdIns(3,4)P2 may have multiple functions on the inner surface of organelles," Darling said. "This is contrary to the current belief that their functions are always limited to one surface of the cell membrane."

The next step is for Darling and his team to identify the molecular components used for flipping PtdIns(3,4)P2, and develop approaches to test ways to manipulate this potential protein sorting mechanism.


'/>"/>

Contact: Julie Heflin
julie.heflin@louisville.edu
502-852-7987
University of Louisville
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/4/2015)... Jose, California (PRWEB) March 04, 2015 ... becoming a worrisome public health issue worldwide. The rising ... major economic and social burden in both developed and ... globally is projected to rise to 1.5 billion, equating ... 75% of these patients are forecast to come from ...
(Date:3/4/2015)... CA (PRWEB) March 04, 2015 Bird ... commercial, industrial and residential applications now offers its popular ... , The humane, highly efficient bird deterrent ... to match the color and décor of the building ... standard colors—brick red, white, crystal clear, light grey, brown, ...
(Date:3/4/2015)... 2015 Rocket Builders’ “Ready to Rocket” ... that have the best prospect for growth according to ... choose the Ready to Rocket companies, we are looking ... with market opportunity. Prizm Media Inc. is an excellent ... at the right time,” said Reg Nordman, Managing Partner, ...
(Date:3/3/2015)... (PRWEB) March 04, 2015 ... facilities design and construction event for New England, ... Massachusetts announced key building envelope related workshops. Sessions ... Workshops include: , Curtain Walls for ... many health care and laboratory facilities are often ...
(Date:3/3/2015)... NOVAtime Technology, Inc. ( http://www.novatime.com ... Attendance / Workforce Management solutions, announced that Innovative ... Workforce Management / Time and Attendance system ... , Since 2004, Innovative Services’ mission has been ... best quality of life. The company is committed ...
Breaking Medicine News(10 mins):Health News:Aging Population Drives Demand for Blood Pressure Monitoring & Measurement Instruments, According to a New Report by Global Industry Analysts, Inc. 2Health News:Aging Population Drives Demand for Blood Pressure Monitoring & Measurement Instruments, According to a New Report by Global Industry Analysts, Inc. 3Health News:Aging Population Drives Demand for Blood Pressure Monitoring & Measurement Instruments, According to a New Report by Global Industry Analysts, Inc. 4Health News:Plastic Bird Spikes Now Come in 7 Colors to Blend in With Their Surroundings 2Health News:Healthcare Lead Generation Leader Prizm Media Inc. is “Ready to Rocket” 2Health News:Healthcare Lead Generation Leader Prizm Media Inc. is “Ready to Rocket” 3Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 2Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 3Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 4Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 5Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 6Health News:Innovative Services, Inc. Successfully Migrates to Cloud-Based NOVAtime Workforce Management Solution to Support Growth and Improve Payroll Processing Time 2Health News:Innovative Services, Inc. Successfully Migrates to Cloud-Based NOVAtime Workforce Management Solution to Support Growth and Improve Payroll Processing Time 3
... Students Harassed by School Administrators encouraged to Call for ... American,Life League,s sixth annual National Pro-life T-shirt Day. This ... County, Pennsylvania with a,concert featuring bands Failure to Excel ... Valley Pregnancy Center., "Music is a great way ...
... The nonprofit Los Angeles,Jewish Home announced today the ... to serve adults 55 and over who are experiencing,mental ... opening of the 10-bed center comes at a time ... their beds across,Southern California. The most recent was the ...
... asthma, SPRINGFIELD, Ill., April 28 Does your ... have an opportunity to,attend a summer camp designed specifically ... therapists and,physicians? The American Lung Association of Illinois is ... two sites this year.,During the week of July 6-11, ...
... Most to Women and Role ... NEW YORK, April 28 In a unique collaboration,between ... MDP ) and NBC Universal (NYSE: GE ) today ... 3,000 women that covered a wide,range of important topics to ...
... April 28 Tenet Healthcare,Corporation (NYSE: THC ... Hahnemann University Hospital and St. Christopher,s Hospital for,Children, ... of Excellence., The Circle of Excellence honors ... levels in the past year in the areas ...
... measurable gains in those with moderate to severe disease ... specialized cells found in the human eye into areas ... able to reduce symptoms and improve quality of life ... new treatment, dubbed Spheramine, reduced symptoms experienced when people ...
Cached Medicine News:Health News:American Life League Kicks Off Sixth Annual National Pro-Life T-Shirt Day With Rock For Life Concert 2Health News:American Life League Kicks Off Sixth Annual National Pro-Life T-Shirt Day With Rock For Life Concert 3Health News:American Life League Kicks Off Sixth Annual National Pro-Life T-Shirt Day With Rock For Life Concert 4Health News:Los Angeles Jewish Home Unveils Auerbach Behavioral Health Center Filling Community Void for Adults Over 55 2Health News:Los Angeles Jewish Home Unveils Auerbach Behavioral Health Center Filling Community Void for Adults Over 55 3Health News:Study Reveals Women Feeling Growing Financial Pressures on Family Life 2Health News:Study Reveals Women Feeling Growing Financial Pressures on Family Life 3Health News:Study Reveals Women Feeling Growing Financial Pressures on Family Life 4Health News:Study Reveals Women Feeling Growing Financial Pressures on Family Life 5Health News:Study Reveals Women Feeling Growing Financial Pressures on Family Life 6Health News:Hahnemann University Hospital and St. Christopher's Hospital for Children Receive Prestigious Tenet Circle of Excellence Award 2Health News:Hahnemann University Hospital and St. Christopher's Hospital for Children Receive Prestigious Tenet Circle of Excellence Award 3Health News:Hahnemann University Hospital and St. Christopher's Hospital for Children Receive Prestigious Tenet Circle of Excellence Award 4Health News:Eye Cell Implants Improve Parkinson's Symptoms 2Health News:Eye Cell Implants Improve Parkinson's Symptoms 3
(Date:3/3/2015)... 3, 2015 Registration is officially open for MEDTEC ... 2015 at the Shenzhen Convention & Exhibition Center. The ... latest to join the MEDTEC China family of events. MEDTEC ... aims to better serve the South China ... is an important region for China,s ...
(Date:3/3/2015)... WASHINGTON , March 3, 2015 ... nationwide effort sponsored by America,s biopharmaceutical research companies, ... features and functionality to provide patients and caregivers ... than 475 public and private patient assistance programs. ... PPA has provided a platform to engage, educate ...
(Date:3/3/2015)... , March 3, 2015  The eleventh annual ... than 450 of the world,s top research scientists, academics, oncologists ... evolving theories and learn about new outcomes in patient ... Each year Ventana Medical Systems, Inc. ... Group, sponsors the Tucson Symposium at the Hilton El ...
Breaking Medicine Technology:Pre-registration Open for 2015 MEDTEC China South 2Pre-registration Open for 2015 MEDTEC China South 3Partnership for Prescription Assistance Relaunches Website with New Features for Patients and Caregivers 2Global scientific collaborators to explore latest pathology and oncology advancements at Tucson Symposium 2
... 8, 2011 Hologic, Inc. (Hologic or the ... and supplier of premium diagnostics products, medical imaging systems and ... will focus on new, ready to market technologies in women,s ... the annual meeting of the European Society of Radiology in ...
... the Third Quarter of 2010, The Board of Directors of ... the company name to iMD Companies, Inc. In addition, a ... objective of propelling the company into the health and wellness ... structure of the firm to that of a holding company. ...
Cached Medicine Technology:Hologic Targets Women's Health Professionals at ECR 2011 2Hologic Targets Women's Health Professionals at ECR 2011 3Hologic Targets Women's Health Professionals at ECR 2011 4Hologic Targets Women's Health Professionals at ECR 2011 5ICBU Announces Corporate Reorganization and Business Plan 2ICBU Announces Corporate Reorganization and Business Plan 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: