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UofL receives $3.15 million grant from Helmsley Charitable Trust
Date:8/5/2010

tobacco-derived carcinogens contributes to the development of lung cancer in smokers.

"Plant-based pharmaceutical systems have a number of advantages," said Dr. Donald Miller, director of the James Graham Brown Cancer Center. "The costs for starting materials are low, which translates into a lower production cost. The materials are readily available, meaning that we are able to increase production levels relatively quickly. Additionally, plant-based therapies have fewer issues with potential contamination than those utilizing other materials such as animal or human pathogens."

The collaboration between UofL and OMHS is greatly enhanced because of Kentucky BioProcessing (KBP), located in Owensboro. KBP is a world leader in the development and execution of scalable processes for commercial scale production of plant-made pharmaceuticals. Established by OMHS in 2006, KBP has developed a network of relationships with leading PMP researchers from across the globe.

"We have a tremendous amount of resources in the Owensboro region to assist in the research to develop new therapies to prevent or treat cancer," said Jeff Barber, Dr. PH, president and chief executive officer of OMHS. "It is exciting that we have the opportunity to develop cancer cures that could someday benefit patients around the globe."

The Owensboro Cancer Research Program is devoted to unlocking the potential of plant-made pharmaceuticals. The research and drug development program takes advantage of the natural products and agricultural industries in the Owensboro region to address diseases impacting the area, especially those that are tobacco-related. Ultimately, the partnership's goal is to create less expensive drugs for cancer prevention and treatment.

Right now researchers with the James Graham Brown Cancer Center and OCRP are working to develop a second-generation cervical cancer vaccine grown in tobacco plants in order to make it affordable to million
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Contact: Lauren Williams
lauren.williams@louisville.edu
502-852-7461
University of Louisville
Source:Eurekalert

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