Navigation Links
Untreated Depression May Cut Shingles Vaccine Effectiveness
Date:2/14/2013

THURSDAY, Feb. 14 (HealthDay News) -- Doctors often urge older patients to get the shingles vaccine because it can prevent or cut the severity of this viral disease. But according to a new study, the vaccine may be less effective in people with untreated depression.

Based on their findings, researchers from the University of California, Los Angeles, suggested the diagnosis and treatment of depression in older people could increase the effectiveness of the shingles vaccine and reduce the risks associated with this painful skin condition. Shingles -- marked by an inflamed rash -- is caused by the reactivation of the virus that causes chickenpox.

The study involved 40 people age 60 or older who were diagnosed with a major depressive disorder. Over the course of two years, the researchers examined the immune response of these patients to the shingles vaccine and compared them to 52 people who were the same age and gender but did not suffer from depression. The participants' immune responses were measured when the study began, then again six weeks later, one year and two years after receiving the vaccine, or an inactive placebo.

The findings, published online Feb. 14 in the journal Clinical Infectious Diseases, revealed that people who had untreated depression had lower immunity to the virus and were less able to respond to the shingles vaccine than those who were not depressed or were taking medications to treat their depression.

The researchers concluded that untreated depression reduced the effectiveness of the shingles vaccine. Antidepressants, however, seemed to "normalize the immune response to the zoster [shingles] vaccine," study leader Dr. Michael Irwin said in a journal news release.

The study authors pointed out that antidepressants increased the effectiveness of the vaccine even when they did not ease a person's symptoms of depression.

While the study found an association between untreated depression and reduced effectiveness of the shingles vaccine, it did not prove a cause-and-effect relationship.

"Efforts are also needed to identify and diagnose depressed elderly patients who might benefit from either a more potent vaccine or a multi-dose vaccination schedule," Irwin noted in the news release.

In addition, more studies are needed to investigate the link between untreated depression and the risk for shingles, the researchers suggested. The link could have far-reaching implications if antidepressants increase the effectiveness of other vaccines, such as the flu shot, for people with depression, they pointed out.

Older adults are at greater risk for shingles, and more than a million new cases occur in the United States every year, according to background information in the news release.

More information

The U.S. Centers for Disease Control and Prevention provides more information on the shingles vaccine.

-- Mary Elizabeth Dallas

SOURCE: Clinical Infectious Diseases, news release, Feb. 14, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study suggests link between untreated depression and response to shingles vaccine
2. Untreated Food Allergies More Likely in Poor, Minority Kids
3. Pain From Sexual Assault Often Untreated, Study Says
4. Untreated Rabies May Not Be Lethal for All, Study Says
5. Untreated Heartburn May Raise Risk for Esophageal Cancer, Study Says
6. High Rates of Untreated Kidney Failure Seen in Elderly
7. Many poor pregnant women with HIV go untreated for depression
8. 1 in 5 Americans Has Untreated Cavities: CDC
9. Depression risk among women in the military deployed after childbirth
10. Alcohol abusers depression often related to drinking
11. Maternal Depression, Violence at Home May Raise Childs ADHD Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Untreated Depression May Cut Shingles Vaccine Effectiveness 
(Date:8/18/2017)... ... August 18, 2017 , ... ... services to communities in east Texas, is launching a regional charity effort to ... Founded in 1991, the Pediatric Brain Tumor Foundation (PBTF) has raised nearly $30 ...
(Date:8/18/2017)... Bedford, TX (PRWEB) , ... August 18, 2017 , ... ... serves communities in the Dallas/Fort Worth area, is spearheading a regional charity campaign organized ... her husband. , In early June of this year, Christina and her children returned ...
(Date:8/18/2017)... ... 2017 , ... Alcovit, a lime-flavored beverage that rids the body of toxins ... product now available through Jet.com. , After 25 years of development, the company ... designed to quickly detox the body thereby avoiding alcohol-induced hangovers. Whether you’re having fun ...
(Date:8/18/2017)... , ... August 18, 2017 , ... “Dangerous Inheritance”: a ... author, Diane Winters. Diane is from Southwest Nebraska where she was raised on ... and family. The story is fictional, but the friendships and mantra of ‘neighbors ...
(Date:8/18/2017)... ... August 18, 2017 , ... Rollon Skin ... anti-aging skincare solutions, recently announced the launch of two new skincare products, ... yet effective alternative to expensive plastic surgery or in-patient cosmetic dermatological procedures. , ...
Breaking Medicine News(10 mins):
(Date:8/4/2017)... -- Agragen, LLC, a Cincinnati -based ... and aquacultural feed sectors, announces a significant step ... AGR131.  This drug is designed to trap and ... patients suffering from inflammatory conditions such as rheumatoid ... Biological pharmaceuticals currently used ...
(Date:8/2/2017)...   Marshall County Hospital in Benton, Kentucky has added ... hospital-acquired infections (HAIs). The new addition, Tru-D SmartUVC , short for "total room ultraviolet ... such as C. diff , MRSA, MERS, Ebola and more. ... Tru-D SmartUVC ... Tru-D in action in a patient room ...
(Date:8/1/2017)...   CerSci Therapeutics , a non-opioid drug development ... has received notice from the National Institute on Drug ... that it has been awarded a Direct-to-Phase II Small ... 2017 with an additional $1,000,000 to follow in 2018. ... of their lead non-opioid drug candidate CT-044 to the ...
Breaking Medicine Technology: