Navigation Links
Unstable chromosome regions are the origin of yeast's brewing capacity
Date:5/14/2010

The ability of yeast cells to convert sugar to alcohol, the key process in the production of beer and wine, can be attributed to a remarkable evolutionary process. The genes that allow yeast to digest sugars in fruits and grains have been duplicated several times over the course of time allowing for optimal conversion of different types of sugars (such as sucrose and maltose) into alcohol. The duplications arose because the genes for sugar processing are situated close to the unstable margin of the chromosome. The phenomenon appears not to be limited to alcohol production in yeast, but forms an important principle in the evolution of living organisms. The results are presented in a study by Kevin Verstrepen from K.U.Leuven and VIB, a life sciences institute in Flanders, Belgium, Andrew Murray from Harvard University, and Chris Brown, a joint student of Verstrepen and Murray.. The prominent journal Current Biology unveils the study.

Duplication of existing genes is an important evolutionary process

Living beings evolve generation after generation because their genetic material changes gradually. It remains a mystery how life, in a relatively short time, develops completely new properties. It is unlikely that they just appear out of nothing. Recent research, amongst others by VIB-scientists, showed that the duplication of existing genes can play a crucial role. One copy can retain the original function of the gene while the new copy may develop a new function. This can sometimes be very different from the original gene.

Living on the edge increases your chances of being duplicated

In the new study, Chris Brown, a PhD student in Verstrepens lab, shows that some genes that are closely located in the ends of the chromosomes, are duplicated more often. The ends of chromosomes, called subtelomeres, seem to function as evolutionary laboratories of our cells. New genes are continuously developed and tested in these "gene nurseries".

Duplication process is of great importance for beer yeast

It appears that duplication at the subtelomeres already occurred in the ancestor of our industrial beer and wine yeasts- Modern strains of beer yeast contain five to ten copies of a prehistoric gene that allows for some sugars to be digested. Each of these modern copies ensures that yeast can digest a particular sugar, and this is much faster than the prehistoric yeast. The massive duplications occurred probably around the Cretaceous era (66 to 145 million years ago). It was no coincidence that this involved the same period in which sweet fruits and grains developed. The duplication of the genes and the further evolution thereof, allowed yeast cells to digest the different sugars in the fruits. In this way, the subtelomeric "gene copying laboratory" ensured that yeasts were able to conquer a new niche. Interestingly, it seems likely that similar subtelomeric gene duplication also stimulates evolution and adaptation in higher organisms, including humans.


'/>"/>

Contact: Joris Gansemans
joris.gansemans@vib.be
32-472-594-067
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

Related medicine news :

1. Womens Chromosomes May Affect Blood Pressure
2. Infectious Virus Hides In Human Chromosomes During Latency And Can Be Passed From Parents To Their Children
3. Males Y Chromosome Not in Decline
4. NIH study confirms location of stem cells near cartilage-rich regions in bones
5. Sisters of Bon Secours Plays Active Role in Bringing Healthcare to Regions of Peru
6. Scientists map out regulatory regions of genome, hot spots for diabetes genes
7. Alzheimers memory problems originate with protein clumps floating in the brain, not amyloid plaques
8. Breast Cancers Return in Original Tumor Site a Bad Sign
9. Top Scientists Explore the Origin of Life in Annual Lasker Lecture at Scripps Research Institute Florida Campus
10. Australia Souvenir Gift Shop Donates 10% Of Profits To Help Aboriginal Children
11. New Exhibition Hall Devoted to Human Origins Opens at National Museum of Natural History
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... December 02, 2016 , ... Lori G. Cohen and ... will speak at the American Conference Institute’s 21st Drug & Medical Device Litigation ... Lead Sponsor of the conference. , Cohen, who chairs the firm’s Pharmaceutical, Medical Device ...
(Date:12/2/2016)... ... 2016 , ... More than 100 business, civic, community and ... the UNCF Dothan-Wiregrass Mayor’s Luncheon Dec. 9, 2016. This inaugural event, hosted by ... support to UNCF-member institutions, including Miles College, Oakwood University, Tuskegee University, Stillman College ...
(Date:12/2/2016)... ... 2016 , ... The annual time frame to change Medicare health and prescription ... December 7th. Currently-enrolled Medicare beneficiaries who are looking to switch from their current plan ... to make changes during this period order for their new policy to go into ...
(Date:12/2/2016)... ... December 02, 2016 , ... Dr. Raffi Hovsepian, ... included in the 2016 “Guide to America’s Top Plastic Surgeons” for seven consecutive ... of their education, experience, and professional associations. , One the most frequently ...
(Date:12/2/2016)... Hawaii (PRWEB) , ... December 02, 2016 , ... ... 2016 at the Hyatt Regency Waikiki Beach Resort and Spa in Honolulu, offering ... in the field of pain management. , The demand for supplemental training ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... in the ECG Cables And ECG Leadwires Market owing to ... devices. On the other hand, the Asia-Pacific ... rate during the forecast period. The market players ... plc ( Ireland ), Koninklijke Philips N.V. ( ... ( China ), held major share of the ...
(Date:12/2/2016)... 2016 Quantum Radiology,s Mobile Breast Center (QR ... directly to women at the workplace, thereby maximizing convenience ... Delta Air Lines and SunTrust Bank, and community health ... of wellness initiatives. "I think it,s a ... them to have a mammogram without taking a large ...
(Date:12/2/2016)... Dec. 2, 2016  Eli Lilly and Company (NYSE: ... for 2017 and provide updated financial guidance for 2016 ... a conference call on that day with the investment ... guidance. The conference call will begin at ... can access a live webcast of the conference call ...
Breaking Medicine Technology: