Navigation Links
Unsaturated fat breakdown leads to complications of acute pancreatitis in obese patients
Date:11/2/2011

the researchers combined healthy pancreatic cells with the unsaturated fatty acids in a test tube, the pancreatic cells died.

Then, they induced pancreatitis in obese mice and found that like the human patients, they had high amounts of fat in their pancreases. The fat in obese mice was mostly unsaturated. Kidneys of the mice with pancreatitis were damaged and contained fat deposits, an unexpected finding supported by studies in human autopsy tissue. Infusing unsaturated fatty acids into the bloodstream of the animals leads to lung injury akin to the problems seen in human patients, while administration of saturated fatty acids does not.

"Now that we better understand why these complications arise, we might be able to prevent them and reduce deaths," Dr. Singh said. "We must find ways to stop this toxic process from happening."

He and his team are studying ways to prevent the generation of unsaturated fatty acids in obese rodents to see what happens when they develop acute pancreatitis.


'/>"/>
Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Adding monounsaturated fats to a low-cholesterol diet can further improve levels
2. Adding Monounsaturated Fats to Diet May Boost Heart Health
3. Polyunsaturated Fats Really May Lower Heart Risk
4. Step in breakdown of HIV proteins essential to recognition, destruction of infected cells
5. ASU leads $5 million NIH-sponsored research initiative to advance diabetes care and treatment
6. Rise in Vulvar Precancers Leads to New Guidelines
7. Project leads next decade of aging research across Europe
8. Project leads next decade of ageing research across Europe
9. X-ray protein probe leads to potential anticancer tactic
10. Insulation from public pressure leads to more accurate suicide reporting by death investigators
11. Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... TX (PRWEB) , ... August 28, 2015 , ... For ... Center is taking part with their subsidiary USPI Tenet Health. , The American Heart ... fight heart disease and stroke. They believe that together, a difference can be made. ...
(Date:8/28/2015)... Hanover, MA (PRWEB) , ... August 28, 2015 , ... ... benefitting the renowned Brain Aneurysm Foundation has added yet another accolade to its ... Chicago, Rahm Emanuel. , “With the help of the medical community and ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... high grade protein with zero fat, carbs, sugar, gluten, lactose or caffeine in ... finalist for the 2015 SupplySide CPG Editor’s Choice Awards. , Five consumer packaged ...
(Date:8/28/2015)... Boynton Beach, FL. (PRWEB) , ... August 28, ... ... creating problems for businesses nationwide. Addictions specialist, Dr. James Strawbridge, gives a new ... Strawbridge believes that it should begin with the employer and employees getting together ...
(Date:8/28/2015)... ... August 28, 2015 , ... CARF ... its adolescent residential, counseling, day treatment and intensive family based services. , By ... for quality and its pursuit of excellence. As a nonprofit charity for more ...
Breaking Medicine News(10 mins):Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 3Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3Health News:West Ridge Academy Awarded CARF Three-Year Accrediation 2
... learn whether protein supplements and cycling during treatments can ... function, thanks to a $2.1 million grant from the ... failure face many health problems. They are at high ... and they also develop a peculiar condition called vascular ...
... a model of stroke A team of researchers, led ... identified a way to preserve nerve cells in a rat model ... of oxygen to part of the brain as a result of ... leads to nerve cell death, although the exact mechanisms underlying ischemic ...
... shoulder muscles in elderly patients is often discouraged because of ... Rush University Medical Center has shown that minimally invasive, or ... study has just been published online in Arthroscopy: ... appear in the October issue. "In people over the ...
... study of Ewing,s sarcoma that screened hundreds of genes based ... anti-cancer drug targets, according to a scientific paper by the ... journal Molecular Cancer . Ewing,s sarcomas are rare, ... bones of teenagers. They represent nearly 3 percent of all ...
... the probability of dying in road accidents on the basis ... Their conclusions are clear reducing the time between an ... from 25 to 15 minutes would cut the risk of ... until the emergency medical services arrive is 25 minutes in ...
... Faith based schools are on the rise in ... values at odds with legislation on equality? Research that ... Leadership published by SAGE shows what happens when school ... consequences for gay students and staff. The UK ...
Cached Medicine News:Health News:Will extra protein and exercise help dialysis patients? U of I profs get $2.1 million to find out 2Health News:Will extra protein and exercise help dialysis patients? U of I profs get $2.1 million to find out 3Health News:JCI online early table of contents: Sept. 1, 2010 2Health News:JCI online early table of contents: Sept. 1, 2010 3Health News:JCI online early table of contents: Sept. 1, 2010 4Health News:JCI online early table of contents: Sept. 1, 2010 5Health News:JCI online early table of contents: Sept. 1, 2010 6Health News:Surgery to repair torn shoulder muscles in the elderly can reduce pain and improve function 2Health News:TGen finds therapeutic targets for rare cancer in children 2Health News:10 minutes could prevent one-third of road deaths 2Health News:Keeping faith -- schools must balance ethos with equality 2
(Date:8/28/2015)... , Aug. 28, 2015 ... has announced the addition of the "Investigation ... to their offering. Originally discovered by ... Yoshitomi Pharmaceutical Industries, Ltd) as an inflammatory drug, ... Senju Pharmaceutical Co., Ltd under the trade name ...
(Date:8/28/2015)... -- Research and Markets ( ... "12th Annual Report and Survey of Biopharmaceutical ... offering. The 2015 12th Annual Report ... is the most recent study of biotherapeutic developers ... capacity and production. The report contains the industry,s ...
(Date:8/28/2015)... , Aug. 28, 2015  Today, in final ... (CDC) Contact Lens Health Week, 1-800 Contacts is sharing ... found that contact lens wearers who do not properly ... risk for eye infections. Most contact ... lenses, but a clean lens case is sometimes overlooked.  ...
Breaking Medicine Technology:Investigation Report on China's Pranoprofen Market, 2010-2019 212th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production 21-800 Contacts Shares Tips on How to Clean Lens Cases 2
... August 21 The medicated pain relief ... Medicines Consortium (SMC) for,restricted use within NHS ... http://www.scottishmedicines.org.uk/smc/5850.html . This,reversal of the previous SMC ... lidocaine medicated plaster) is based on significant ...
... Aug. 21 Johnson & Johnson Pharmaceutical,Research ... the U.S. Food,and Drug Administration (FDA) requires ... New Drug Application (NDA) for DORIBAX(TM),(doripenem for ... known as nosocomial pneumonia (NP), including ventilator-associated,pneumonia ...
Cached Medicine Technology:Shingles Pain Treatment Will Benefit More Patients 2Shingles Pain Treatment Will Benefit More Patients 3Shingles Pain Treatment Will Benefit More Patients 4FDA Requires Additional Information on DORIBAX for Treatment of Hospital-Acquired Pneumonia 2FDA Requires Additional Information on DORIBAX for Treatment of Hospital-Acquired Pneumonia 3FDA Requires Additional Information on DORIBAX for Treatment of Hospital-Acquired Pneumonia 4FDA Requires Additional Information on DORIBAX for Treatment of Hospital-Acquired Pneumonia 5
TeleRehab Advantage is a monitoring system that automates the generation of outcomes data. Patient information and session information is automatically transferred from the monitoring program to Outc...
... Clearly, the ISI Lexan ... versatile surgical table for lower ... orthopaedic, head and neck, and ... optional traction package gives you ...
MagaCell-Streptavidin is a streptavidin coupled to magnetizable cellulose/iron oxide particles...
Streptavidin A-Beads are polydisperse 1.8 m paramagnetic particles covalently coupled with streptavidin. The paramagnetic particles remain in solution over extended periods of time. Mixing is require...
Medicine Products: