Navigation Links
Unrealistic optimism appears common in early cancer trials
Date:1/24/2011

(Garrison, NY) Can optimism be ethically problematic? Yes, according to a new study, which found unrealistic optimism prevalent among participants in early-phase cancer trials and suggested that it may compromise informed consent.

Many cancer researchers and ethicists assume that hope and optimism in the research context are "always ethically benign, without considering the possibility that they reflect a bias," write the authors of the study, which appears in IRB: Ethics & Human Research. "Others have claimed that unrealistic expectations for benefit are a result of misunderstanding and that the proper response to them is to provide patient-subjects with more information" But the study cast doubt on both assumptions.

The study included 72 patients with cancer who were enrolled in early-phase oncology trials in the New York metropolitan area between August 2008 and October 2009. Questionnaires assessed signs of unrealistic optimism, as well as participants' understanding of the trials' purpose. Unrealistic optimism, which social psychologists define as being specific to a situation and consider a form of bias, is distinct from "dispositional optimism," which is a general outlook on life and is neither realistic nor unrealistic. Individuals can have one form of optimism without the other.

Study respondents exhibited unrealistic optimism in response to three of five questions about the likelihood of particular events happening to them compared with other trial participants: having their cancer controlled by drugs administered in the trials, experiencing a health benefit from the drugs in the trials, and not experiencing a health problem from the drugs in the trials.

However, a substantial majority of the respondents 72 percent accurately understood that the purpose of t
'/>"/>

Contact: Michael Turton
turtonm@thehastingscenter.org
845-424-4040 x242
The Hastings Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Optimism Could Help Kids Keep Depression at Bay
2. Optimism May Boost Immune System
3. Optimism boosts the immune system
4. Minimally invasive technique appears helpful to reanimate facial paralysis
5. Timely Surgery Appears to Cut Infection Risk, Costs
6. Rare, Severe Form of Morning Sickness Appears to Be Genetic
7. Sleep Appears to Aid Learning
8. Chronic Constipation Appears to Be Increasing Among Kids
9. Home Monitoring of Blood-Thinner Use Appears Effective
10. Treatment of retinal conditions appears to have changed significantly in previous decade
11. IV Aspirin Drip Appears to Be Safe, Effective for Migraine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Europe is one of the largest consumers of micro ... area. The agricultural sector is a significant user of ... the total water use. The scale and importance of ... far from negligible in most northern ones. , In ... the water use in most countries, while in the ...
(Date:7/11/2014)... July 11, 2014 Pigments are insoluble ... mainly three functions namely protective coating, opacity, and coloring. ... materials that impart color to substances such as paper, ... the pigments, which upon application impart color to the ... oxide, carbon black, and hematite. , The coloring action ...
(Date:7/11/2014)... Using electronic health records to understand the best available ... is more efficient and less costly for taxpayers than ... Research led by Professor van Staa, carried out while ... Datalink (CPRD) and who is now based at The ... Health Technology Assessment ( HTA ) today (Friday ...
(Date:7/11/2014)... Mexico (PRWEB) July 11, 2014 Experience ... the Mayan Heritage Experience Package at the luxury all-inclusive ... the package include a guided on-site ecological family tour ... well as The Coba Mayan Encounter Tour at the ... Nohoch Muul, the tallest pyramid in the Yucatan and ...
(Date:7/11/2014)... July 11, 2014 WWTrek Human Outreach ... Kilimanjaro Kids Community in Tanzania. Opened in 2012, the KKC ... and two cows. HOP Founder, Dean Cardinale, started the KKC ... of the orphaned children he encountered while running treks on ... the children, who have all made astounding progress in school ...
Breaking Medicine News(10 mins):Health News:Europe Micro Irrigation System Market Driven by Growing Environmental Concerns and Decreasing Water Availability - New Report by MicroMarket Monitor 2Health News:Europe Micro Irrigation System Market Driven by Growing Environmental Concerns and Decreasing Water Availability - New Report by MicroMarket Monitor 3Health News:Americas Pigments Market Worth 1,099 Thousand MT by 2018 - New Report by MicroMarket Monitor 2Health News:Americas Pigments Market Worth 1,099 Thousand MT by 2018 - New Report by MicroMarket Monitor 3Health News:Better use of electronic health records makes clinical trials less expensive 2Health News:Explore the Aura and Mystery of the Yucatan’s Mayan Culture with New Hotel Package at AAA Five Diamond Grand Velas Riviera Maya 2Health News:Explore the Aura and Mystery of the Yucatan’s Mayan Culture with New Hotel Package at AAA Five Diamond Grand Velas Riviera Maya 3Health News:Human Outreach Project Sees Incredible Progress in the Kilimanjaro Kids Community 2
... have embarked on a multi-city tour offering passengers access to ... in New York, Boston and,Philadelphia, passengers in Washington, D.C. can ... *Passengers will be taken to any ... a maximum value of $25 per ride. , ...
... this phenomenon is tied to more aggressive disease, researchers say ... promote the growth of new nerves that are associated with ... that prostate cancer follows the growth of nerves, but this ... promote nerve growth, says a team at Baylor College of ...
... clots, researchers at the University of Oklahoma Health Sciences Center ... but seems to play a primary role in how cancer ... in recent issues of the journal Blood and ... research group at OU led by Patrick McKee first discovered ...
... behind the ravages of old age and in doing ... fighting cancer in younger persons can actually promote cancer ... biological cells stop dividing in response to stress or ... secretion of proteins that cause inflammation in neighboring cells ...
... Dec. 3 A patient who was surgically implanted,with ... promoted,by Medtronic, suffocated due to severe throat and neck ... and Page Perry, LLC who filed the lawsuit,in California ... The Complaint alleges, among other ...
... , ... (PRWEB) November 2, 2009 -- For the remainder of ... , to UK mainland addresses, excluding the highlands and islands, will be ... web site. , , ,Hyperdrug director Ben Watson says "Hyperdrug intends to ...
Cached Medicine News:Health News:The Makers of TYLENOL(R) Warming Liquids Offer Free 'Warming' Taxi Rides in Washington, D.C. 2Health News:Prostate Cancer Stimulates Nerve Growth 2Health News:Researchers discover new enzyme in cancer growth 2Health News:Cellular senescence a double-edged sword 2Health News:Cellular senescence a double-edged sword 3Health News:Cellular senescence a double-edged sword 4Health News:Cellular senescence a double-edged sword 5Health News:Medtronic, Inc. and Medtronic Sofamor Danek, USA, Inc. Sued for Product Liability and Promoting the Off-Label Use of Infuse(R) Bone Graft Product, According to Page Perry, LLC 2Health News:Beating the Credit Crunch with Hyperdrug.co.uk 2
(Date:7/11/2014)... , July 11, 2014 Research and ... "Global and Chinese Medical X-ray Film Industry Report 2014" ... http://photos.prnewswire.com/prnh/20130307/600769 Global And Chinese Medical ... in-depth study on the current state of the Global ... Chinese situation. The report provides a basic overview ...
(Date:7/11/2014)... 11, 2014 According to ... Composition of Material, Application (Healthcare, Homeland security, Industrial ... (Personal Instrument, Hand-Held Instruments, Fixed, and Installed Instruments) ... 2013 - 2020", published by MarketsandMarkets, the Scintillator Market is ... from 2014 to 2020, and reach $479.16 Million ...
(Date:7/11/2014)... Research and Markets  has announced the addition of ... to their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... needle commonly used with a syringe to inject substances ... it. A hypodermic needle is used for rapid delivery ... ingested. Hypodermic needles are broadly classified into non-safety and ...
Breaking Medicine Technology:Global and Chinese Medical X-ray Film Industry Report 2014 2Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 3
... Reportlinker.com announces that a new market research ... Advanced Drug Delivery Markets (Liposomes, Polymers and ... Drug delivery is evolving at a ... discovered frequently. Advanced drug delivery deals with developing ...
... Jan. 11, 2011 Reportlinker.com announces that a ... catalogue: France Pharmaceutical Market Overview ... http://www.reportlinker.com/p0360215/France-Pharmaceutical-Market-Overview-–--Austerity-measures-will-impact-pharmaceutical-market-growth.html ... pharma market in France was valued at $38.8bn ...
Cached Medicine Technology:Reportlinker Adds Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies) 2Reportlinker Adds Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies) 3Reportlinker Adds France Pharmaceutical Market Overview - Austerity measures will impact pharmaceutical market growth 2
The Sabre 2400 provides high power performance and key user features to meet today's demanding electrosurgical needs. It is an ideal general-purpose electrosurgical generator....
Designed to use all advantages of bipolar technique. C-2600 MP recommended to all specialties that uses the benefits of the bipolar techniques....
Finesse electrosurgical generator (100-120 VAC) utilizes a patented design that integrates the electrosurgical generator and smoke evacuation system into a single compact unit....
NS2000 Bipolar Generator provides precise coagulation without tissue sticking....
Medicine Products: