Navigation Links
Unraveling the 'Mad Cow' Mystery
Date:11/20/2009

Key molecule identified by researchers

FRIDAY, Nov. 20 (HealthDay News) -- Researchers may be moving closer to better treatments for bovine spongiform encephalopathy, better known as mad cow disease, and the related condition called Creutzfeldt Jakob disease.

A protein called Glypican-1 is crucial to the development of mad cow disease, researchers from England now report, and understanding its role could help scientists figure out how to stop the illness from progressing.

The findings were published Nov. 20 in the journal PLoS Pathogens..

Abnormal forms of proteins known as prions cause mad cow disease, a killer infection that causes neurological problems. It hasn't been clear, however, why the proteins go awry.

The researchers found that the presence of the Glypican-1 protein boosts the number of abnormal prion proteins.

"We were looking at how the normal prion protein functions in cells and spotted that it was interacting with something," Nigel Hooper, a professor of biochemistry at the University of Leeds, who participated in the research, said in a statement. "Some lateral thinking and deduction led us to Glypican-1, and when we carried out the experiment, we found we were right."

Hooper added: "Now that we know the identity of one of the key molecules in the disease process, we may in the future be able to design drugs that target this."

More information

Learn more about mad cow disease from the U.S. Centers for Disease Control and Prevention.



-- Randy Dotinga



SOURCE: Public Library of Science, news release, Nov. 19, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Unraveling the Link Between Genes and Environment
2. Physics, Math Provide Clues to Unraveling Cancer
3. March of Dimes Awards $250,000 Prize to Scientists Unraveling the Causes of Muscular Dystrophy
4. Research may unlock mystery of autisms origin in the brain
5. Scientists solve mystery of polyketide drug formation
6. Dying bats in the Northeast remain a mystery
7. New White Paper from The Beryl Institute: Mystery Shopping the Patient Experience
8. MYSTERY ER Season 2 Takes Viewers Behind the Curtain for Real-Life Medical Mysteries on Discovery Health
9. Catalyst mystery unlocked
10. Why do eyelids sag with age? UCLA study answers mystery
11. Scientists Unravel Mystery of Tamoxifen Resistance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department ... in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at ... Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
(Date:6/24/2016)... Texas (PRWEB) , ... June 24, 2016 , ... ... International Conference and Scientific Sessions in Dallas that it will receive two significant ... of the grants came as PHA marked its 25th anniversary by recognizing patients, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... Georgia (PRWEB) , ... June 24, 2016 , ... ... awards today at the Clinical Decision Making in Emergency Medicine conference in Ponte ... have authored journal articles published in Emergency Medicine Practice and Pediatric ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ... company developing innovative inhaled drugs, announced today that it ... Russell Investments reconstituted its comprehensive set of U.S. ... "This is an important milestone for Pulmatrix," said ... increase shareholder awareness of our progress in developing drugs ...
(Date:6/23/2016)... , June 23, 2016 Any dentist who ... challenges of the current process. Many of them do not ... the technical difficulties and high laboratory costs involved. And those ... offer it at such a high cost that the majority ... Dr. Parsa Zadeh , founder of Dental ...
(Date:6/23/2016)... 2016 Capricor Therapeutics, Inc. ... biotechnology company focused on the discovery, development and ... enrollment in its ongoing randomized HOPE-Duchenne clinical trial ... of its 24-patient target. Capricor expects the trial ... of 2016, and to report top line data ...
Breaking Medicine Technology: