Navigation Links
Unmasking the deadly secrets of pancreatic cancer
Date:10/25/2012

A large-scale study that defines the complexity of underlying mutations responsible for pancreatic cancers in more than 100 patients was published in Nature today.

The analysis represents the first report from Australia's contribution to the International Cancer Genome Consortium (ICGC), which brings together the world's leading scientists to identify the genetic drivers behind 50 different cancer types.

Pancreatic cancer has the highest mortality rate of all the major cancers and is one of the few for which survival has not improved substantially over the past 40 years. It is the fourth-leading cause of cancer death.

Professor Sean Grimmond, from the Institute for Molecular Bioscience (IMB) at The University of Queensland, and Professor Andrew Biankin, from The Kinghorn Cancer Centre at Sydney's Garvan Institute of Medical Research/ St. Vincent's Hospital led an international team of more than 100 researchers that sequenced the genomes of 100 pancreatic tumours and compared them to normal tissue to determine the genetic changes that lead to this cancer.

"We found over 2,000 mutated genes in total, ranging from the KRAS gene, which was mutated in about 90 per cent of samples, to hundreds of gene mutations that were only present in 1 or 2 per cent of tumours," Professor Grimmond said.

"So while tumours may look very similar under the microscope, genetic analysis reveals as many variations in each tumour as there are patients.

"This demonstrates that so-called 'pancreatic cancer' is not one disease, but many, and suggests that people who seemingly have the same cancer might need to be treated quite differently."

Professor Biankin said such individual genetic diagnoses and treatments represent the future of healthcare.

"In this study, we found a set of genes, the axon guidance pathway, that is frequently damaged in pancreatic cancer patients and is associated with a potentially poor
'/>"/>

Contact: Iris Hui
iris.hui@researchaustralia.org
61-292-958-545
Research Australia
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New tools help nursing homes track and prevent deadly infections
2. Genome-wide scan maps mutations in deadly lung cancers; reveals embryonic gene link
3. Deadly witch hunts targeted by grassroots womens groups
4. Missed Diagnoses in ICU Often Have Deadly Results: Review
5. Microbiology and Genome Experts Quell Deadly Bacteria Outbreak
6. Deadly outbreak of West Nile virus highlights urgent need for more research, funding
7. Weekend hospital stays prove more deadly than other times for older people with head trauma
8. New Vaccine May Offer Protection From Deadly Nipah Virus
9. AuCoin gets $600,000 to refine new test for deadly bacterial infection melioidosis
10. UT Southwestern study suggests new treatment target for deadly brain tumors
11. Tornadoes Dont Have to Be Deadly, Experts Say
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2014)... 23, 2014 A team of New York ... longer when preceded by surgery and delivered by an experienced ... new study. Click here to read it now . ... cases of mesothelioma patients who underwent hemithoracic (one ... dose to the shape of a tumor. Patients who ...
(Date:8/23/2014)... 23, 2014 GBI Research, the leading ... Care Therapeutics in Major Developed Markets to 2020 - ... Drive Market”, which provides in-depth analysis of the critical ... Spain, Japan and Canada. The report provides an estimation ... to 2020. It covers critical care indications that are ...
(Date:8/23/2014)... Young adults in Athens, GA who find that they ... the phone and call the new helpline which can offer support ... , Troubled Teen Athens is a wonderful resource for an adolescent ... necessary steps to end substance abuse once and for all. When ... friends or peers when really they should put their faith in ...
(Date:8/23/2014)... NC (PRWEB) August 23, 2014 Teen substance ... young people in Holly Springs, NC. Countless adolescents throughout North ... regular basis. Unfortunately, many never receive professional rehab due ... adults on where to get help. Troubled Teens Holly Springs ... the lives of local teenage alcohol abusers in ...
(Date:8/22/2014)... 2014 2014 Deep Research Report ... and in-depth research report on the Glucose Meter ... including Glucose Meter definition, classification, application, and industry ... research covers the international market analysis, including domestic ... macroeconomic environment & economic situation analysis. The report ...
Breaking Medicine News(10 mins):Health News:New Study Links Hospital Experience and Prior Surgery with Mesothelioma Radiation Success, According to Surviving Mesothelioma 2Health News:Critical Care Therapeutics in Major Developed Markets to 2020 | Researchmoz 2Health News:Critical Care Therapeutics in Major Developed Markets to 2020 | Researchmoz 3Health News:Teenagers in Athens, GA are Locating Addiction Recovery Thanks to New Helpline 2Health News:New Helpline Provides Teen Drug & Alcohol Recovery Information in Holly Springs, NC 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 3
... IRVINE, Calif., June 26 ISTA Pharmaceuticals, Inc. (Nasdaq: ... Ophthalmic Drugs Advisory Committee appointed by the U.S. Food ... (bepotastine besilate ophthalmic solution) 1.5% as an eye drop ... The Committee voted unanimously 7 to 0 in favor ...
... Caraco Pharmaceutical Laboratories, Ltd. (NYSE Amex: CPD ), ... information in regards to our financial position in light of ... to the FDA action are currently being identified. The early ... $15 to $20 million. , , The products subject ...
... announced today that it will hold its 2009 Annual General ... Meeting of Shareholders (the "Special Meeting") on August 5, 2009. ... asked to vote in favor of certain matters related to ... Subject to shareholder approval and the approval of the ...
... , CASTRES, France, June ... Committee for Medicinal Products for Human Use,(CHMP), the ... has issued a positive opinion supporting approval and ... monotherapy in metastatic,treatment of bladder cancer (advanced or ...
... June 26 Today Sentry Data Systems, Inc. announced ... Pharmacy and Revenue Cycle Management application. Claims Guardian ... their bills for unusual, missing, or errant charges that ... , "We believe that automatically matching actual procurement ...
... Healthcare ... the second straight year. The list is sponsored by the Greater Omaha Chamber of Commerce and ... , ... Healthcare staffing company Medical Solutions has landed on the Best Places to ...
Cached Medicine News:Health News:Dermatologic and Ophthalmic Drugs Advisory Committee Unanimously Recommends Bepreve(TM) for the Treatment of Ocular Itching Associated with Allergic Conjunctivitis 2Health News:Dermatologic and Ophthalmic Drugs Advisory Committee Unanimously Recommends Bepreve(TM) for the Treatment of Ocular Itching Associated with Allergic Conjunctivitis 3Health News:Caraco Pharmaceutical Laboratories, Ltd. Updates on Financial Position 2Health News:Warner Chilcott to Hold 2009 Annual General Meeting of Shareholders and Special Court-Ordered Meeting of Shareholders 2Health News:Positive CHMP Opinion for JAVLOR(R) in Metastatic Treatment of Bladder Cancer After Failure of a Prior Platinum-Containing Regimen 2Health News:Positive CHMP Opinion for JAVLOR(R) in Metastatic Treatment of Bladder Cancer After Failure of a Prior Platinum-Containing Regimen 3Health News:Sentry Data Systems Announces Claims Guardian(TM) 2Health News:Sentry Data Systems Announces Claims Guardian(TM) 3Health News:Healthcare Staffing Company Medical Solutions Named Among "2009 Best Places to Work in Omaha" 2Health News:Healthcare Staffing Company Medical Solutions Named Among "2009 Best Places to Work in Omaha" 3Health News:Healthcare Staffing Company Medical Solutions Named Among "2009 Best Places to Work in Omaha" 4
(Date:8/22/2014)... Calif. , Aug. 22, 2014  WaferGen Bio-systems, ... underwritten public offering of units of common stock and ... gross proceeds of $20 million, prior to deducting underwriting ... Company.  The shares and warrants are immediately separable and ... are expected to begin trading on The NASDAQ Stock ...
(Date:8/21/2014)... 21, 2014   Memorial Hermann Health System and ... today announced a new partnership to provide a new level ... care centers in the greater Houston ... become the exclusive provider of professional breast radiology services for ... Memorial City, The Woodlands , Northeast, Southwest ...
(Date:8/21/2014)... Nektar Therapeutics (NASDAQ: NKTR ... results from its Phase 3 pivotal clinical trial ... factor VIII (rFVIII) treatment for hemophilia A based ... primary endpoint in reducing annualized bleed rates (ABR) ... arm. Top-line results from the prospective, ...
Breaking Medicine Technology:WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 2WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 3WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 4Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 2Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 3Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 4Baxter Announces Positive Top-Line Results from Its Phase 3 Study of BAX 855, Extended Half-Life Recombinant FVIII for Hemophilia A Patients 2Baxter Announces Positive Top-Line Results from Its Phase 3 Study of BAX 855, Extended Half-Life Recombinant FVIII for Hemophilia A Patients 3Baxter Announces Positive Top-Line Results from Its Phase 3 Study of BAX 855, Extended Half-Life Recombinant FVIII for Hemophilia A Patients 4Baxter Announces Positive Top-Line Results from Its Phase 3 Study of BAX 855, Extended Half-Life Recombinant FVIII for Hemophilia A Patients 5
Spoon end periosteal, polished finish, designed for large mucoperiosteal flaps....
Love-Adson periosteal elevator, semi sharp, blade width 3/16" (5 mm), length 6 1/2" (165 mm)....
Key periosteal elevators, blade width 1" (25 mm), total length 7 1/2" (191 mm)....
Hoen periosteal elevators, No.3, blade width 3/4" (20 mm), total length 7 1/2" (191 mm)....
Medicine Products: